Get Spliced: Uniting Alternative Splicing and Arthritis.

Autor: van Haaren, Maurice J. H.¹ (AUTHOR), Steller, Levina Bertina¹ (AUTHOR), Vastert, Sebastiaan J.^1,2 (AUTHOR), Calis, Jorg J. A.¹ (AUTHOR), van Loosdregt, Jorg¹ (AUTHOR) j.vanloosdregt@umcutrecht.nl

Publikováno v: International Journal of Molecular Sciences. Aug2024, Vol. 25 Issue 15, p8123. 28p.

Deciphering the role of immune cell composition in epigenetic age acceleration: Insights from cell‐type deconvolution applied to human blood epigenetic clocks.

Autor: Zhang, Ze^1,2,3 (AUTHOR), Reynolds, Samuel R.¹ (AUTHOR), Stolrow, Hannah G.^1,2 (AUTHOR), Chen, Ji‐Qing^1,4 (AUTHOR), Christensen, Brock C.^1,2,3,4 (AUTHOR), Salas, Lucas A.^1,2,3,4 (AUTHOR) lucas.a.salas@dartmouth.edu

Publikováno v: Aging Cell. Mar2024, Vol. 23 Issue 3, p1-16. 16p.

SNP Variants in Major Histocompatibility Complex Are Associated with Sarcoidosis Susceptibility-A Joint Analysis in Four European Populations.

Autor: Wolin A; Transplantation Laboratory, Medicum, University of Helsinki, Helsinki, Finland., Lahtela EL; Transplantation Laboratory, Medicum, University of Helsinki, Helsinki, Finland., Anttila V; Analytical and Translational Genetics Unit, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland., Petrek M; Department of Pathological Physiology and Institute of Molecular and Translational Medicine, Faculty of Medicine and Dentistry, Palacky University Olomouc, Olomouc, Czech Republic., Grunewald J; Respiratory Medicine Unit, Department of Medicine Solna and CMM, Karolinska Institutet, Karolinska University Hospital, Solna, Sweden., van Moorsel CHM; Department of Pulmonology, St. Antonius Hospital Nieuwegein, Heart and Lung Center, University Medical Center Utrecht, Utrecht, Netherlands., Eklund A; Respiratory Medicine Unit, Department of Medicine Solna and CMM, Karolinska Institutet, Karolinska University Hospital, Solna, Sweden., Grutters JC; Department of Pulmonology, St. Antonius Hospital Nieuwegein, Heart and Lung Center, University Medical Center Utrecht, Utrecht, Netherlands., Kolek V; Department of Respiratory Medicine, Faculty of Medicine and Dentistry, Palacky University Olomouc, Olomouc, Czech Republic., Mrazek F; Department of Immunology, Faculty of Medicine and Dentistry, Palacky University Olomouc, Olomouc, Czech Republic., Kishore A; Department of Pathological Physiology, Faculty of Medicine and Dentistry, Palacky University Olomouc, Olomouc, Czech Republic., Padyukov L; Rheumatology Unit, Department of Medicine, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden., Pietinalho A; Raasepori Health Care Centre, Raasepori, Finland., Ronninger M; Respiratory Medicine Unit, Department of Medicine Solna and CMM, Karolinska Institutet, Karolinska University Hospital, Solna, Sweden., Seppänen M; Rare Disease Center, Children's Hospital and Adult Immunodeficiency Unit, Inflammation Center, Helsinki University and Helsinki University Hospital, Helsinki, Finland., Selroos O; University of Helsinki, Helsinki, Finland., Lokki ML; Transplantation Laboratory, Medicum, University of Helsinki, Helsinki, Finland.

Publikováno v: Frontiers in immunology [Front Immunol] 2017 Apr 19; Vol. 8, pp. 422. Date of Electronic Publication: 2017 Apr 19 (Print Publication: 2017).

High-Density Genetic Mapping Identifies New Susceptibility Variants in Sarcoidosis Phenotypes and Shows Genomic-driven Phenotypic Differences.

Autor: Rivera NV; 1 Respiratory Unit, Department of Medicine, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden.; 2 Center for Molecular Medicine, and., Ronninger M; 1 Respiratory Unit, Department of Medicine, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden.; 2 Center for Molecular Medicine, and., Shchetynsky K; 2 Center for Molecular Medicine, and.; 3 Rheumatology Unit, Department of Medicine, Karolinska Institutet, Stockholm, Sweden., Franke A; 4 Institute of Clinical Molecular Biology, University Hospital Schleswig-Holstein, Campus Kiel and Kiel University, Kiel, Germany., Nöthen MM; 5 Institute of Human Genetics, and.; 6 Department of Genomics, Life & Brain Center, University of Bonn, Bonn, Germany., Müller-Quernheim J; 7 Department of Pneumology, University of Freiburg, Freiburg, Germany., Schreiber S; 4 Institute of Clinical Molecular Biology, University Hospital Schleswig-Holstein, Campus Kiel and Kiel University, Kiel, Germany.; 8 Popgen Biobank and.; 9 Clinic of Internal Medicine I, University Hospital Schleswig-Holstein, Kiel, Germany., Adrianto I; 10 Arthritis and Clinical Immunology Research Program, Oklahoma Medical Research Foundation, Oklahoma City, Oklahoma., Karakaya B; 11 Center of Interstitial Lung Diseases, St. Antonius Hospital, Nieuwegein, the Netherlands., van Moorsel CH; 11 Center of Interstitial Lung Diseases, St. Antonius Hospital, Nieuwegein, the Netherlands.; 12 Division of Heart & Lungs, University Medical Center Utrecht, Utrecht, the Netherlands., Navratilova Z; 13 Department of Pathological Physiology and., Kolek V; 14 Department of Respiratory Medicine, Faculty of Medicine and Dentistry, Palacky University Olomouc, Olomouc, Czech Republic., Rybicki BA; 15 Department of Public Health Sciences, Henry Ford Health Systems, Detroit, Michigan; and., Iannuzzi MC; 16 State University of New York Upstate Medical University Syracuse, Syracuse, New York., Petrek M; 13 Department of Pathological Physiology and., Grutters JC; 11 Center of Interstitial Lung Diseases, St. Antonius Hospital, Nieuwegein, the Netherlands.; 12 Division of Heart & Lungs, University Medical Center Utrecht, Utrecht, the Netherlands., Montgomery C; 10 Arthritis and Clinical Immunology Research Program, Oklahoma Medical Research Foundation, Oklahoma City, Oklahoma., Fischer A; 4 Institute of Clinical Molecular Biology, University Hospital Schleswig-Holstein, Campus Kiel and Kiel University, Kiel, Germany., Eklund A; 1 Respiratory Unit, Department of Medicine, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden., Padyukov L; 2 Center for Molecular Medicine, and.; 3 Rheumatology Unit, Department of Medicine, Karolinska Institutet, Stockholm, Sweden., Grunewald J; 2 Center for Molecular Medicine, and.; 3 Rheumatology Unit, Department of Medicine, Karolinska Institutet, Stockholm, Sweden.

Publikováno v: American journal of respiratory and critical care medicine [Am J Respir Crit Care Med] 2016 May 01; Vol. 193 (9), pp. 1008-22.

Identification of Immune-Relevant Factors Conferring Sarcoidosis Genetic Risk.

Autor: Fischer A; 1 Institute of Clinical Molecular Biology, Kiel University and University Hospital Schleswig-Holstein, Kiel, Germany., Ellinghaus D; 1 Institute of Clinical Molecular Biology, Kiel University and University Hospital Schleswig-Holstein, Kiel, Germany., Nutsua M; 1 Institute of Clinical Molecular Biology, Kiel University and University Hospital Schleswig-Holstein, Kiel, Germany., Hofmann S; 1 Institute of Clinical Molecular Biology, Kiel University and University Hospital Schleswig-Holstein, Kiel, Germany., Montgomery CG; 2 Arthritis and Clinical Immunology Research Program, Oklahoma Medical Research Foundation, Oklahoma City, Oklahoma., Iannuzzi MC; 3 Department of Medicine, Upstate Medical University, Syracuse, New York., Rybicki BA; 4 Department of Public Health Sciences, Henry Ford Hospital, Detroit, Michigan., Petrek M; 5 Faculty of Medicine and Dentistry, Palacky University, Olomouc, Czech Republic., Mrazek F; 5 Faculty of Medicine and Dentistry, Palacky University, Olomouc, Czech Republic., Pabst S; 6 Pneumologische Praxis, Bonn, Germany., Grohé C; 7 Department of Respiratory Medicine, Evangelische Lungenklinik Berlin-Buch, Berlin, Germany., Grunewald J; 8 Respiratory Medicine Unit, Department of Medicine and CMM, Karolinska Institutet and Karolinska University Hospital, Stockholm, Sweden., Ronninger M; 8 Respiratory Medicine Unit, Department of Medicine and CMM, Karolinska Institutet and Karolinska University Hospital, Stockholm, Sweden., Eklund A; 8 Respiratory Medicine Unit, Department of Medicine and CMM, Karolinska Institutet and Karolinska University Hospital, Stockholm, Sweden., Padyukov L; 9 Rheumatology Unit, Department of Medicine, Karolinska Institutet, Stockholm, Sweden., Mihailovic-Vucinic V; 10 Department of Sarcoidosis and Other Granulomatous Diseases and., Jovanovic D; 11 Thoracic Oncology and ILD Department, University Hospital of Pulmonology, Clinical Center of Serbia, Belgrade, Serbia., Sterclova M; 12 Department of Respiratory Medicine, Thomayer Hospital and 1 Medical Faculty and., Homolka J; 13 1st Lung Department, Prague General Hospital, Charles University, Prague, Czech Republic., Nöthen MM; 14 Institute of Human Genetics and.; 15 Department of Genomics, Life & Brain Center, University of Bonn, Bonn, Germany., Herms S; 14 Institute of Human Genetics and.; 15 Department of Genomics, Life & Brain Center, University of Bonn, Bonn, Germany.; 16 Genomics Group, Medical Genetics, Department of Biomedicine, University of Basel, Basel, Switzerland., Gieger C; 17 Institute of Epidemiology II and.; 18 Research Unit of Molecular Epidemiology, Helmholtz Center Munich, Munich, Germany., Strauch K; 19 Institute of Genetic Epidemiology and.; 20 Institute of Medical Informatics, Biometry and Epidemiology and., Winkelmann J; 21 Institute of Human Genetics, Helmholtz Center Munich, German Research Center for Environmental Health, Neuherberg, Germany.; 22 Institute of Human Genetics, MRI.; 23 Department of Neurology, MRI, and., Boehm BO; 24 Department of Internal Medicine I, Ulm University Medical Centre, Ulm, Germany.; 25 LKCMedicine, Nanyang Technological University, Singapore.; 26 Imperial College London, London, United Kingdom., Brand S; 27 Department of Medicine II-Grosshadern, Ludwig-Maximilians-University, Munich, Germany., Büning C; 28 Department of Gastroenterology, Hepatology and Endocrinology, Charité, Campus Mitte, Berlin, Germany., Schürmann M; 29 Institute of Human Genetics, University of Lübeck, Lübeck, Germany., Ellinghaus E; 1 Institute of Clinical Molecular Biology, Kiel University and University Hospital Schleswig-Holstein, Kiel, Germany., Baurecht H; 31 Graduate School of Information Science in Health, Technische Universität München, Munich, Germany.; 30 Department of Dermatology, Allergology, and Venerology, and., Lieb W; 32 Institute of Epidemiology and Popgen Biobank, Kiel University, Kiel, Germany; and., Nebel A; 1 Institute of Clinical Molecular Biology, Kiel University and University Hospital Schleswig-Holstein, Kiel, Germany., Müller-Quernheim J; 33 Department of Pneumology, University of Freiburg, Freiburg, Germany., Franke A; 1 Institute of Clinical Molecular Biology, Kiel University and University Hospital Schleswig-Holstein, Kiel, Germany., Schreiber S; 1 Institute of Clinical Molecular Biology, Kiel University and University Hospital Schleswig-Holstein, Kiel, Germany.; 34 Clinic of Internal Medicine I, University Hospital Schleswig-Holstein, Campus Kiel, Kiel, Germany.

Publikováno v: American journal of respiratory and critical care medicine [Am J Respir Crit Care Med] 2015 Sep 15; Vol. 192 (6), pp. 727-36.