Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Ronnie T P Poon"'
Autor:
Julja Burchard, Chunsheng Zhang, Angela M Liu, Ronnie T P Poon, Nikki P Y Lee, Kwong‐Fai Wong, Pak C Sham, Brian Y Lam, Mark D Ferguson, George Tokiwa, Ryan Smith, Brendan Leeson, Rebecca Beard, John R Lamb, Lee Lim, Mao Mao, Hongyue Dai, John M Luk
Publikováno v:
Molecular Systems Biology, Vol 6, Iss 1, Pp 1-12 (2010)
Abstract Tumorigenesis involves multistep genetic alterations. To elucidate the microRNA (miRNA)–gene interaction network in carcinogenesis, we examined their genome‐wide expression profiles in 96 pairs of tumor/non‐tumor tissues from hepatocel
Externí odkaz:
https://doaj.org/article/50bc46a5e0da45ebb7e123909cce0639
Autor:
Tan To Cheung, Ronnie T P Poon, Kenneth S H Chok, Albert C Y Chan, Simon H Y Tsang, Wing Chiu Dai, Thomas C C Yau, See Ching Chan, Sheung Tat Fan, Chung Mau Lo
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e94453 (2014)
Background and aimSpontaneous rupture of hepatocellular carcinoma (HCC) carries a high mortality. The use of radiofrequency ablation (RFA) in recent years has enriched the armamentarium for hemostasis of spontaneously ruptured HCCs but its results ha
Externí odkaz:
https://doaj.org/article/34267574a94d4c5386e85725f46312a4
Autor:
Enders K O Ng, Rufina Li, Vivian Y Shin, Hong Chuan Jin, Candy P H Leung, Edmond S K Ma, Roberta Pang, Daniel Chua, Kent-Man Chu, W L Law, Simon Y K Law, Ronnie T P Poon, Ava Kwong
Publikováno v:
PLoS ONE, Vol 8, Iss 1, p e53141 (2013)
BackgroundWe previously showed microRNAs (miRNAs) in plasma are potential biomarkers for colorectal cancer detection. Here, we aimed to develop specific blood-based miRNA assay for breast cancer detection.Methodology/principal findingsTaqMan-based mi
Externí odkaz:
https://doaj.org/article/3c87d7ece03e488f909bf810f0b4c798
Autor:
James Fung, Ronnie T P Poon, Wan-Ching Yu, See-Ching Chan, Albert C Y Chan, Kenneth S H Chok, Tan-To Cheung, Wai-Kay Seto, Chung-Mau Lo, Ching-Lung Lai, Man-Fung Yuen
Publikováno v:
PLoS ONE, Vol 8, Iss 8, p e72306 (2013)
BackgroundLiver stiffness measurement (LSM) using transient elastography has recently become available for the assessment of liver fibrosis. Whether LSM can predict the functional liver reserve in patients undergoing liver resection is not certain.Ai
Externí odkaz:
https://doaj.org/article/91e13935388241ac85e4a9adccfbe75b
Autor:
Yonggang Wang, Felix H Shek, Kwong F Wong, Ling Xiao Liu, Xiao Qian Zhang, Yi Yuan, Ester Khin, Mei-Yu Hu, Jian Hua Wang, Ronnie T P Poon, Wanjin Hong, Nikki P Lee, John M Luk
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e72386 (2013)
Cadherin-17 (CDH17) is an oncofetal molecule associated with poor prognostic outcomes of hepatocellular carcinoma (HCC), for which the treatment options are very limited. The present study investigates the therapeutic potential of a monoclonal antibo
Externí odkaz:
https://doaj.org/article/541a922c573b4e4fa86211a45660f3b1
Autor:
Xiao Qi Wang, Ray Kit Ng, Xiaoyan Ming, Wu Zhang, Lin Chen, Andrew C Y Chu, Roberta Pang, Chung Mau Lo, Sai Wah Tsao, Xuqing Liu, Ronnie T P Poon, Sheung Tat Fan
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e72435 (2013)
Activation of the stem cell transcriptional circuitry is an important event in cancer development. Although cancer cells demonstrate a stem cell-like gene expression signature, the epigenetic regulation of pluripotency-associated genes in cancers rem
Externí odkaz:
https://doaj.org/article/f2988211e6244dcc96e5a996fb8f9468
Autor:
Kevin T P Ng, Dong Yong Guo, Qiao Cheng, Wei Geng, Chang Chun Ling, Chang Xian Li, Xiao Bing Liu, Yuen Yuen Ma, Chung Mau Lo, Ronnie T P Poon, Sheung Tat Fan, Kwan Man
Publikováno v:
PLoS ONE, Vol 7, Iss 2, p e31655 (2012)
BACKGROUND: Hepatocellular carcinoma (HCC) is highly malignant and metastatic. Currently, there is no effective chemotherapy for patients with advanced HCC leading to an urgent need to seek for novel therapeutic options. We aimed to investigate the e
Externí odkaz:
https://doaj.org/article/c93d614cd5f14ead8258b6a97d9234f8
Autor:
John R Lamb, Chunsheng Zhang, Tao Xie, Kai Wang, Bin Zhang, Ke Hao, Eugene Chudin, Hunter B Fraser, Joshua Millstein, Mark Ferguson, Christine Suver, Irena Ivanovska, Martin Scott, Ulrike Philippar, Dimple Bansal, Zhan Zhang, Julja Burchard, Ryan Smith, Danielle Greenawalt, Michele Cleary, Jonathan Derry, Andrey Loboda, James Watters, Ronnie T P Poon, Sheung T Fan, Chun Yeung, Nikki P Y Lee, Justin Guinney, Cliona Molony, Valur Emilsson, Carolyn Buser-Doepner, Jun Zhu, Stephen Friend, Mao Mao, Peter M Shaw, Hongyue Dai, John M Luk, Eric E Schadt
Publikováno v:
PLoS ONE, Vol 6, Iss 7, p e20090 (2011)
BackgroundIn hepatocellular carcinoma (HCC) genes predictive of survival have been found in both adjacent normal (AN) and tumor (TU) tissues. The relationships between these two sets of predictive genes and the general process of tumorigenesis and di
Externí odkaz:
https://doaj.org/article/b53d4a768873417aa36a0629f6eecc3f
Autor:
Wei Geng, Kevin T P Ng, Chris K W Sun, Wing Lung Yau, Xiao Bing Liu, Qiao Cheng, Ronnie T P Poon, Chung Mau Lo, Kwan Man, Sheung Tat Fan
Publikováno v:
PLoS ONE, Vol 6, Iss 11, p e27362 (2011)
AIMS: We previously demonstrated Proline rich tyrosine kinase 2 (Pyk2) plays important roles in regulating tumor progression, migration and invasion in hepatocellular carcinoma (HCC). In this study, we aimed to examine the role of proline rich tyrosi
Externí odkaz:
https://doaj.org/article/cfe4562e3aff40f7940d97566807f07c
Autor:
Irena Ivanovska, Chunsheng Zhang, Angela M Liu, Kwong F Wong, Nikki P Lee, Patrick Lewis, Ulrike Philippar, Dimple Bansal, Carolyn Buser, Martin Scott, Mao Mao, Ronnie T P Poon, Sheung Tat Fan, Michele A Cleary, John M Luk, Hongyue Dai
Publikováno v:
PLoS ONE, Vol 6, Iss 9, p e24582 (2011)
Biomarkers derived from gene expression profiling data may have a high false-positive rate and must be rigorously validated using independent clinical data sets, which are not always available. Although animal model systems could provide alternative
Externí odkaz:
https://doaj.org/article/1a6968a013d74f12988b1620ffe531a4