Zobrazeno 1 - 10
of 51
pro vyhledávání: '"Ronnie P.-A. Berntsson"'
Publikováno v:
mBio, Vol 15, Iss 8 (2024)
ABSTRACT Conjugative type 4 secretion systems (T4SSs) are the main driver for the spread of antibiotic resistance genes and virulence factors in bacteria. To deliver the DNA substrate to recipient cells, it must cross the cell envelopes of both donor
Externí odkaz:
https://doaj.org/article/1891a97f66644beeb54b01ed2744fc9f
Autor:
Lena Lassinantti, Martha I. Camacho, Rebecca J. B. Erickson, Julia L. E. Willett, Nicholas R. De Lay, Josy ter Beek, Gary M. Dunny, Peter J. Christie, Ronnie P.-A. Berntsson
Publikováno v:
mSphere, Vol 6, Iss 3 (2021)
Bacteria utilize type 4 secretion systems (T4SS) to efficiently transfer DNA between donor and recipient cells, thereby spreading genes encoding antibiotic resistance as well as various virulence factors. Regulation of expression of the T4SS proteins
Externí odkaz:
https://doaj.org/article/b45233d4c2af46d99368ccd5a946fd06
Publikováno v:
Frontiers in Microbiology, Vol 11 (2020)
Surface proteins in Gram-positive bacteria are often involved in biofilm formation, host-cell interactions, and surface attachment. Here we review a protein module found in surface proteins that are often encoded on various mobile genetic elements li
Externí odkaz:
https://doaj.org/article/6ba9097f813746098e75a11d4ecd2471
Autor:
Sicai Zhang, Ronnie P.-A. Berntsson, William H. Tepp, Liang Tao, Eric A. Johnson, Pål Stenmark, Min Dong
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
Botulinum neurotoxins (BoNTs) are thought to require complex gangliosides, a group of glycosphingolipids, as essential co-receptors to target neurons. Here, the authors show that BoNT/DC represents an exception to this rule and that an extended loop
Externí odkaz:
https://doaj.org/article/1ace838b4bf145588cda2cd87b10cd11
Autor:
Liang Tao, Lisheng Peng, Ronnie P.-A. Berntsson, Sai Man Liu, SunHyun Park, Feifan Yu, Christopher Boone, Shilpa Palan, Matthew Beard, Pierre-Etienne Chabrier, Pål Stenmark, Johannes Krupp, Min Dong
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-10 (2017)
Humans are less sensitive to the therapeutic effects of botulinum neurotoxin B (BoNT/B) than the animal models it is tested on due to differences between the human and the mouse receptors. Here, the authors engineer BoNT/B to improve its affinity to
Externí odkaz:
https://doaj.org/article/c4a98be4d71a49939f118b13ff4c9b03
Autor:
Saima Rehman, Yang Grace Li, Andreas Schmitt, Lena Lassinantti, Peter J. Christie, Ronnie P.-A. Berntsson
Publikováno v:
Frontiers in Microbiology, Vol 10 (2019)
The conjugative plasmid pCF10 from Enterococcus faecalis encodes a Type 4 Secretion System required for plasmid transfer. The accessory factor PcfF and relaxase PcfG initiate pCF10 transfer by forming the catalytically active relaxosome at the plasmi
Externí odkaz:
https://doaj.org/article/8c1b9b7514fd417db8c6113951d87756
Autor:
Akbar Espaillat, Laura Alvarez, Gabriel Torrens, Josy ter Beek, Vega Miguel-Ruano, Oihane Irazoki, Federico Gago, Juan A. Hermoso, Ronnie P-A. Berntsson, Felipe Cava
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract The bacterial cell-wall peptidoglycan is made of glycan strands crosslinked by short peptide stems. Crosslinks are catalyzed by DD-transpeptidases (4,3-crosslinks) and LD-transpeptidases (3,3-crosslinks). However, recent research on non-mode
Externí odkaz:
https://doaj.org/article/f373c1092527467592fe75b975bb0cf4
Autor:
Wei-Sheng Sun, Lena Lassinantti, Michael Järvå, Andreas Schmitt, Josy ter Beek, Ronnie P-A Berntsson
Publikováno v:
eLife, Vol 12 (2023)
Type 4 Secretion Systems are a main driver for the spread of antibiotic resistance genes and virulence factors in bacteria. In Gram-positives, these secretion systems often rely on surface adhesins to enhance cellular aggregation and mating-pair form
Externí odkaz:
https://doaj.org/article/26a7305a7c2a4aab87ef0f4a36b89364
Autor:
Rima-Maria Rahal, Susann Fiedler, Adeyemi Adetula, Ronnie P.-A. Berntsson, Ulrich Dirnagl, Gordon B. Feld, Christian J. Fiebach, Samsad Afrin Himi, Aidan J. Horner, Tina B. Lonsdorf, Felix Schönbrodt, Miguel Alejandro A. Silan, Michael Wenzler, Flávio Azevedo
Publikováno v:
Nature Human Behaviour. 7:164-167
High-quality research requires appropriate employment and working conditions for researchers. However, many academic systems rely on short-term employment contracts, biased selection procedures and misaligned incentives, which hinder research quality
Type 4 Secretion Systems (T4SSs) are large and versatile protein machineries that facilitate the spread of antibiotic resistance and other virulence factors via horizontal gene transfer. Conjugative T4SSs depend on relaxases to process the DNA in pre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d365aef4afd93e18ab35299fba499f10
http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-204501
http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-204501