Výsledky vyhledávání - "Ronnie, Chee"

Akademický článek

Dendritic Cell-Derived TSLP Negatively Regulates HIF-1α and IL-1β During Dectin-1 Signaling

Autor: Matthew J. Elder, Steve J. Webster, Timothy J. Fitzmaurice, Aran S. D. Shaunak, Martin Steinmetz, Ronnie Chee, Ziad Mallat, E. Suzanne Cohen, David L. Williams, J. S. Hill Gaston, Jane C. Goodall

Publikováno v: Frontiers in Immunology, Vol 10 (2019)

Thymic stromal lymphopoietin (TSLP) is a functionally pleotropic cytokine important in immune regulation, and TSLP dysregulation is associated with numerous diseases. TSLP is produced by many cell types, but has predominantly been characterized as a

Externí odkaz: https://doaj.org/article/d37c0112f5e9441b8aa4a1a774e80bea

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Akademický článek

β-Glucan Size Controls Dectin-1-Mediated Immune Responses in Human Dendritic Cells by Regulating IL-1β Production

Autor: Matthew J. Elder, Steve J. Webster, Ronnie Chee, David L. Williams, J. S. Hill Gaston, Jane C. Goodall

Publikováno v: Frontiers in Immunology, Vol 8 (2017)

Dectin-1/CLEC7A is a pattern recognition receptor that recognizes β-1,3 glucans, and its stimulation initiates signaling events characterized by the production of inflammatory cytokines from human dendritic cells (DCs) required for antifungal immuni

Externí odkaz: https://doaj.org/article/7b61fa02b4424390890f997b33134bad

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Akademický článek

Detection of a microbial metabolite by STING regulates inflammasome activation in response to Chlamydia trachomatis infection.

Autor: Steve J Webster, Sven Brode, Lou Ellis, Timothy J Fitzmaurice, Matthew J Elder, Nelson O Gekara, Panagiotis Tourlomousis, Clare Bryant, Simon Clare, Ronnie Chee, Hill J S Gaston, Jane C Goodall

Publikováno v: PLoS Pathogens, Vol 13, Iss 6, p e1006383 (2017)

The innate immune system is a critical component of host defence against microbial pathogens, but effective responses require an ability to distinguish between infectious and non-infectious insult to prevent inappropriate inflammation. Using the impo

Externí odkaz: https://doaj.org/article/cc7ab21c35704bf99075bec68f1688a5

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Gene therapy for Wiskott-Aldrich syndrome in a severely affected adult

Publikováno v: Blood
Blood, 2017, 130 (11), pp.1327-1335. ⟨10.1182/blood-2017-04-777136⟩
Blood, American Society of Hematology, 2017, 130 (11), pp.1327-1335. ⟨10.1182/blood-2017-04-777136⟩

International audience; Until recently, hematopoietic stem cell transplantation was the only curative option for Wiskott-Aldrich syndrome (WAS). The first attempts at gene therapy for WAS using a Upsilon-retroviral vector improved immunological param

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc04e2ec10605e4bca31f64aac81e7c1
https://doi.org/10.1182/blood-2017-04-777136

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Liver disease in common variable immunodeficiency (CVID) is characterised by a high frequency of portal hypertension and significant burden of inflammatory liver pathology

Autor: Niall Burke, Neil Halliday, Fernando Moreira, Ronnie Chee, Siobhan Burns, David M. Lowe, Douglas Thorburn

Publikováno v: Journal of Hepatology. 73:S66-S67

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::90c881a669f47d05ab4bffb91febebbb
https://doi.org/10.1016/s0168-8278(20)30669-3

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Targeted Gene Panel Sequencing for Early-onset Inflammatory Bowel Disease and Chronic Diarrhea

Autor: Erik-Oliver Glocker, Jan Rohr, Nadia Saleh, Mehrnaz Mesdaghi, Christian Klemann, Robin Kobbe, Natalie Frede, Renate Abt, Peter Hasselblatt, Sigune Goldacker, Ronnie Chee, Naghi Dara, Mary Buchta, Florian Brinkert, Alla Bulashevska, Aisha Elmarsafy, Birol Öztürk, Paul Thankam, Nermeen Galal, Patrick Gerner, Jutta Hammermann, Mahboubeh M. Kharaghani, Katrin Hübscher, Gunda Ruzaike, Jutte Van Der Werff Ten Bosch, Lida Atarod, Safa Baris, Suranjith L. Seneviratne, Ana Cordeiro, Daniel Kotlarz, Sebastian Zeissig, Horst von Bernuth, Britt-Sabina Petersen, Yvonne Zeissig, Milos Jesenak, Gregor Dückers, Andre Franke, João Farela Neves, Sara Sebnem Kilic, Sally G. Mitton, Dietrich August, Zuzana Havlíčeková, Neslihan Edeer Karaca, T. Ronan Leahy, Bodo Grimbacher, Christoph Klein, Hemant Bhavsar, Moudjahed Saleh Al-Ddafari, Ebru Senol, Carsten Speckmann, Jessica L.R. Restrepo, Daniel Tegtmeyer, Ayca Kiykim, Martin W. Laass, Luis F. Pereira, Elif Karakoc-Aydiner

"Çalışmada 57 yazar bulunmaktadır. Bu yazarlardan sadece Bursa Uludağ Üniversitesi mensuplarının girişleri yapılmıştır.” Background: In contrast to adult-onset inflammatory bowel disease (IBD), where many genetic loci have been shown t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1410e31a1932bf36de7f66bbd5614be0
https://hdl.handle.net/20.500.14017/226c4e28-a237-4494-bfb9-0233866baed5

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Detection of a microbial metabolite by STING regulates inflammasome activation in response to Chlamydia trachomatis infection

Autor: Steve J, Webster, Sven, Brode, Lou, Ellis, Timothy J, Fitzmaurice, Matthew J, Elder, Nelson O, Gekara, Panagiotis, Tourlomousis, Clare, Bryant, Simon, Clare, Ronnie, Chee, Hill J S, Gaston, Jane C, Goodall

Publikováno v: PLoS Pathogens

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::5d607aaade192086e743ae6844fad9ce
https://pubmed.ncbi.nlm.nih.gov/28570638

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Escape of Mycobacterium tuberculosis from oxidative killing by neutrophils

Autor: Daniel S. Korbel, Björn Corleis, Ronnie Chee, R. Wilson, Johan Bylund, Ulrich E. Schaible

Publikováno v: Cellular Microbiology. 14:1109-1121

Neutrophils enter sites of infection, where they can eliminate pathogenic bacteria in an oxidative manner. Despite their predominance in active tuberculosis lesions, the function of neutrophils in this important human infection is still highly contro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::52b03197fb3effe30c7ad0e32600a185
https://doi.org/10.1111/j.1462-5822.2012.01783.x

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Hypogammaglobulinaemia

Autor: Patrick F K, Yong, Ronnie, Chee, Bodo, Grimbacher

Publikováno v: Immunology and Allergy Clinics of North America. 28:691-713

This article reviews the primary immunodeficiencies that result in hypogammaglobulinemia or predominantly antibody deficiency disorders. This group makes up the largest proportion of patients with primary immunodeficiency. Significant advances have b

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23ce3d021169e70d782ecc2406b5e382
https://doi.org/10.1016/j.iac.2008.06.003

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Common Variable Immunodeficiency: An Update on Etiology and Management

Autor: Ronnie Chee, M. D. Tarzi, Ignatius Chua, Patrick F.K. Yong, Bodo Grimbacher

Publikováno v: Immunology and Allergy Clinics of North America. 28:367-386

Common variable immunodeficiency (CVID) represents a heterogeneous group of primary antibody deficiency disorders characterized by recurrent infection and by inflammatory, granulomatous, and autoimmune complications. Recently, there have been signifi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4974dda6719f0b2d23984dea50165010
https://doi.org/10.1016/j.iac.2008.01.001

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