Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Ronni Wasmuth"'
Autor:
Timothy L. Chen, Bonnie Harrington, Jean Truxall, Ronni Wasmuth, Alexander Prouty, Shelby Sloan, Amy M. Lehman, Deepa Sampath, Eric Orlemans, Robert A. Baiocchi, Lapo Alinari, John C. Byrd, Jennifer A. Woyach, Erin Hertlein
Publikováno v:
Journal of Hematology & Oncology, Vol 14, Iss 1, Pp 1-5 (2021)
Abstract B-cell receptor (BCR) antagonists such as the BTK inhibitor ibrutinib have proven to effectively target chronic lymphocytic leukemia (CLL) tumor cells, leading to impressive response rates in these patients. However patients do still relapse
Externí odkaz:
https://doaj.org/article/4c01d238e7a84a94ba1ec2e43998f4b6
Autor:
Lindsey T. Brinton, Pu Zhang, Katie Williams, Daniel Canfield, Shelley Orwick, Steven Sher, Ronni Wasmuth, Larry Beaver, Casey Cempre, Jordan Skinner, Matthew Cannon, Mukul Govande, Bonnie Harrington, Amy Lehman, John C. Byrd, Rosa Lapalombella, James S. Blachly
Publikováno v:
Journal of Hematology & Oncology, Vol 13, Iss 1, Pp 1-10 (2020)
Abstract Acute myeloid leukemia (AML) is a heterogeneous and complex disease, and treatments for this disease have not been curative for the majority of patients. In younger patients, internal tandem duplication of FLT3 (FLT3-ITD) is a common mutatio
Externí odkaz:
https://doaj.org/article/f9792135e55a4ec59d467892727b81d0
Autor:
Ola A. Elgamal, Abeera Mehmood, Jae Yoon Jeon, Bridget Carmichael, Amy Lehman, Shelley J. Orwick, Jean Truxall, Virginia M. Goettl, Ronni Wasmuth, Minh Tran, Shaneice Mitchell, Rosa Lapalombella, Sudharshan Eathiraj, Brian Schwartz, Kimberly Stegmaier, Sharyn D. Baker, Erin Hertlein, John C. Byrd
Publikováno v:
Journal of Hematology & Oncology, Vol 13, Iss 1, Pp 1-14 (2020)
Abstract Background Acute myeloid leukemia (AML) is the most common type of adult leukemia. Several studies have demonstrated that oncogenesis in AML is enhanced by kinase signaling pathways such as Src family kinases (SFK) including Src and Lyn, spl
Externí odkaz:
https://doaj.org/article/dd45c2eb4bd348c99ba2f63a9ee816cc
Autor:
Rajeswaran Mani, Swagata Goswami, Bhavani Gopalakrishnan, Rahul Ramaswamy, Ronni Wasmuth, Minh Tran, Xiaokui Mo, Amber Gordon, Donna Bucci, David M. Lucas, Alice Mims, Christopher Brooks, Adrienne Dorrance, Alison Walker, William Blum, John C. Byrd, Gerard Lozanski, Sumithira Vasu, Natarajan Muthusamy
Publikováno v:
Haematologica, Vol 103, Iss 8 (2018)
Diseases with clonal hematopoiesis such as myelodysplastic syndrome and acute myeloid leukemia have high rates of relapse. Only a small subset of acute myeloid leukemia patients are cured with chemotherapy alone. Relapse in these diseases occurs at l
Externí odkaz:
https://doaj.org/article/e97e548ab8d84139bc36320bc12d1d0f
Autor:
Jennifer A. Woyach, Rosa Lapalombella, John C. Byrd, Pearlly Yan, Danielle K. White, Ronni Wasmuth, Lisa L. Smith, Deepa Sampath, Rose Mantel, Parviz Kanga, Zachary A. Hing, Virginia M. Goettl, Ralf Bundschuh, Justin Breitbach, Lianbo Yu, Alexander Pan, Bonnie K. Harrington, Kerry A. Rogers, Fabienne Lucas
Purpose:Aberrant Myc expression is a major factor in the pathogenesis of aggressive lymphoma, and these lymphomas, while clinically heterogeneous, often are resistant to currently available treatments and have poor survival. Myc expression can also b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5018b4badb203541096ba4b3eaff1e04
https://doi.org/10.1158/1078-0432.c.6528003.v1
https://doi.org/10.1158/1078-0432.c.6528003.v1
Autor:
Jennifer A. Woyach, Rosa Lapalombella, John C. Byrd, Pearlly Yan, Danielle K. White, Ronni Wasmuth, Lisa L. Smith, Deepa Sampath, Rose Mantel, Parviz Kanga, Zachary A. Hing, Virginia M. Goettl, Ralf Bundschuh, Justin Breitbach, Lianbo Yu, Alexander Pan, Bonnie K. Harrington, Kerry A. Rogers, Fabienne Lucas
Supplemental Table 4: Abundance information of top 20 CDR3 sequences and top 10 heavy chains and top 10 light chains (see supplemental Excel file) Supplemental Table 5: DESeq2 normalized counts, log2-fold change, and p-values and adjusted p-values fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46d043b9370501e6f6f0432db79a7c14
https://doi.org/10.1158/1078-0432.22471764
https://doi.org/10.1158/1078-0432.22471764
Autor:
Jennifer A. Woyach, Rosa Lapalombella, John C. Byrd, Pearlly Yan, Danielle K. White, Ronni Wasmuth, Lisa L. Smith, Deepa Sampath, Rose Mantel, Parviz Kanga, Zachary A. Hing, Virginia M. Goettl, Ralf Bundschuh, Justin Breitbach, Lianbo Yu, Alexander Pan, Bonnie K. Harrington, Kerry A. Rogers, Fabienne Lucas
Supplemental Figure 1: Commonly used murine cell surface markers of B-cell development Supplemental Figure 2: Multicolor flow cytometry gating strategy and representative flow plots from a WT spleen sample Supplemental Figure 3: Histopathological ass
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5554d034a94e47c52c61b5b513009ac
https://doi.org/10.1158/1078-0432.22471767.v1
https://doi.org/10.1158/1078-0432.22471767.v1
Autor:
Alexander Marr, Soumendrakrishna Karmahapatra, Dominique Corbin, Yerdanos Asemelash, Steven Sher, Shaneice Renee Mitchell, Bonnie K Harrington, Shelley Orwick, Larry Beaver, Ronni Wasmuth, Virginia Goettl, Alice S. Mims, Karilyn T. Larkin, Sumithira Vasu, Meixiao Long, James S. Blachly, Ramiro Garzon, John C. Byrd, Rosa Lapalombella, Nicole Grieselhuber
Publikováno v:
Blood. 140:3075-3076
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::60dfa4fc506d7ca00b0178aa34a0c488
https://doi.org/10.1182/blood-2022-160277
https://doi.org/10.1182/blood-2022-160277
Autor:
Alexander Pan, John C. Byrd, Lianbo Yu, Fabienne Lucas, Zachary A. Hing, Justin T. Breitbach, Parviz Kanga, Rosa Lapalombella, Virginia M. Goettl, Pearlly S. Yan, Ralf Bundschuh, Kerry A. Rogers, Deepa Sampath, Bonnie K. Harrington, Ronni Wasmuth, Lisa L. Smith, Danielle K. White, Jennifer A. Woyach, Rose Mantel
Publikováno v:
Clinical Cancer Research. 25:6260-6273
Purpose:Aberrant Myc expression is a major factor in the pathogenesis of aggressive lymphoma, and these lymphomas, while clinically heterogeneous, often are resistant to currently available treatments and have poor survival. Myc expression can also b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f46e699e92270009865e707b81737c61
https://doi.org/10.1158/1078-0432.ccr-19-0273
https://doi.org/10.1158/1078-0432.ccr-19-0273
Autor:
John C. Byrd, Frank Frissora, Kevan Zapolnik, Xiaokui Mo, Mary K. McKenna, Minh Tran, Rahul Ramaswamy, Vivek M. Rangnekar, Rajeswaran Mani, Ronni Wasmuth, Bonnie K. Harrington, Subbarao Bondada, Joseph T. Greene, Natarajan Muthusamy, Max Yano
Publikováno v:
Blood Advances. 3:1255-1266
Prostate apoptosis response 4 (Par-4) is a tumor suppressor that prevents proliferation and induces cell death in several solid tumors. However, its role in B-cell malignancies has not been elucidated. To describe the role of Par-4 in chronic lymphoc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d85969fde6cc8ea316eb713b8c813388
https://doi.org/10.1182/bloodadvances.2018025973
https://doi.org/10.1182/bloodadvances.2018025973