Insight into the Spatial Arrangement of the Lysine Tyrosylquinone and Cu ²⁺ in the Active Site of Lysyl Oxidase-like 2.

Autor: Meier AA; Department of Chemistry, The University of Kansas, Lawrence, KS 66045, USA., Moon HJ; Department of Chemistry, The University of Kansas, Lawrence, KS 66045, USA., Sabuncu S; Department of Chemical Physiology and Biochemistry, School of Medicine, Oregon Health & Science University, Portland, OR 97239, USA., Singh P; Department of Chemistry, The University of Kansas, Lawrence, KS 66045, USA., Ronnebaum TA; Department of Chemistry, The University of Kansas, Lawrence, KS 66045, USA., Ou S; Department of Chemistry, The University of Kansas, Lawrence, KS 66045, USA., Douglas JT; Department of Chemistry, The University of Kansas, Lawrence, KS 66045, USA., Jackson TA; Department of Chemistry, The University of Kansas, Lawrence, KS 66045, USA., Moënne-Loccoz P; Department of Chemical Physiology and Biochemistry, School of Medicine, Oregon Health & Science University, Portland, OR 97239, USA., Mure M; Department of Chemistry, The University of Kansas, Lawrence, KS 66045, USA.

Publikováno v: International journal of molecular sciences [Int J Mol Sci] 2022 Nov 12; Vol. 23 (22). Date of Electronic Publication: 2022 Nov 12.

Rational inhibitor design for Pseudomonas aeruginosa salicylate adenylation enzyme PchD.

Autor: Shelton CL; Department of Molecular Biosciences, University of Kansas, Lawrence, KS, 66045, USA.; Department of Chemistry and Biochemistry, Northern Kentucky University, Highland Heights, Kentucky, 41099, USA., Meneely KM; Department of Molecular Biosciences, University of Kansas, Lawrence, KS, 66045, USA.; Department of Chemistry, University of Texas San Antonio, San Antonio, TX, 78249, USA., Ronnebaum TA; Department of Chemistry, University of Kansas, Lawrence, KS, 66045, USA.; Roy and Diana Vagelos Laboratories, Department of Chemistry, University of Pennsylvania, Philadelphia, PA, 19104-6323, USA., Chilton AS; Department of Molecular Biosciences, University of Kansas, Lawrence, KS, 66045, USA., Riley AP; Department of Pharmaceutical Sciences, College of Pharmacy, University of Illinois at Chicago, Chicago, IL, 60612, USA.; Department of Medicinal Chemistry, School of Pharmacy, University of Kansas, Lawrence, KS, 66045, USA., Prisinzano TE; Department of Medicinal Chemistry, School of Pharmacy, University of Kansas, Lawrence, KS, 66045, USA.; Department of Pharmaceutical Sciences, College of Pharmacy, University of Kentucky, Lexington, KY, 40536-0596, USA., Lamb AL; Department of Molecular Biosciences, University of Kansas, Lawrence, KS, 66045, USA. audrey.lamb@utsa.edu.; Department of Chemistry, University of Texas San Antonio, San Antonio, TX, 78249, USA. audrey.lamb@utsa.edu.

Publikováno v: Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry [J Biol Inorg Chem] 2022 Sep; Vol. 27 (6), pp. 541-551. Date of Electronic Publication: 2022 May 05.

Assembly-Line Catalysis in Bifunctional Terpene Synthases.

Autor: Faylo JL; Roy and Diana Vagelos Laboratories, Department of Chemistry, University of Pennsylvania, Philadelphia, Pennsylvania 19104-6323, United States., Ronnebaum TA; Roy and Diana Vagelos Laboratories, Department of Chemistry, University of Pennsylvania, Philadelphia, Pennsylvania 19104-6323, United States., Christianson DW; Roy and Diana Vagelos Laboratories, Department of Chemistry, University of Pennsylvania, Philadelphia, Pennsylvania 19104-6323, United States.

Publikováno v: Accounts of chemical research [Acc Chem Res] 2021 Oct 19; Vol. 54 (20), pp. 3780-3791. Date of Electronic Publication: 2021 Jul 13.

Structural studies of geranylgeranylglyceryl phosphate synthase, a prenyltransferase found in thermophilic Euryarchaeota.

Autor: Blank PN; Department of Chemistry, University of Pennsylvania, 231 South 34th Street, Philadelphia, PA 19104, USA., Barnett AA; Department of Biology, DeSales University, 2755 Station Avenue, Center Valley, PA 18034, USA., Ronnebaum TA; Department of Chemistry, University of Pennsylvania, 231 South 34th Street, Philadelphia, PA 19104, USA., Alderfer KE; Department of Chemistry and Physics, DeSales University, 2755 Station Avenue, Center Valley, PA 18034, USA., Gillott BN; Department of Chemistry and Physics, DeSales University, 2755 Station Avenue, Center Valley, PA 18034, USA., Christianson DW; Department of Chemistry, University of Pennsylvania, 231 South 34th Street, Philadelphia, PA 19104, USA., Himmelberger JA; Department of Chemistry and Physics, DeSales University, 2755 Station Avenue, Center Valley, PA 18034, USA.

Publikováno v: Acta crystallographica. Section D, Structural biology [Acta Crystallogr D Struct Biol] 2020 Jun 01; Vol. 76 (Pt 6), pp. 542-557. Date of Electronic Publication: 2020 May 29.

Changes in the allosteric site of human liver pyruvate kinase upon activator binding include the breakage of an intersubunit cation-π bond.

Autor: McFarlane JS; Department of Molecular Biosciences, University of Kansas, 1200 Sunnyside, Lawrence, KS 66045, USA., Ronnebaum TA; Department of Chemistry, University of Kansas, 1200 Sunnyside, Lawrence, KS 66045, USA., Meneely KM; Department of Molecular Biosciences, University of Kansas, 1200 Sunnyside, Lawrence, KS 66045, USA., Chilton A; Department of Molecular Biosciences, University of Kansas, 1200 Sunnyside, Lawrence, KS 66045, USA., Fenton AW; Department of Biochemistry and Molecular Biology, University of Kansas Medical Center, 3901 Rainbow Boulevard, Kansas City, KS 66160, USA., Lamb AL; Department of Molecular Biosciences, University of Kansas, 1200 Sunnyside, Lawrence, KS 66045, USA.

Publikováno v: Acta crystallographica. Section F, Structural biology communications [Acta Crystallogr F Struct Biol Commun] 2019 Jun 01; Vol. 75 (Pt 6), pp. 461-469. Date of Electronic Publication: 2019 Jun 10.