Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Ronnald Vollrath"'
Autor:
Iona Wallace, Kheewoong Baek, J. Rajan Prabu, Ronnald Vollrath, Susanne von Gronau, Brenda A. Schulman, Kirby N. Swatek
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)
Abstract The attachment of the ubiquitin-like protein ISG15 to substrates by specific E1-E2-E3 enzymes is a well-established signalling mechanism of the innate immune response. Here, we present a 3.45 Å cryo-EM structure of a chemically trapped UBE1
Externí odkaz:
https://doaj.org/article/6263318ce67744db9c3234db9bdea50d
Autor:
Jens Smiatek, Imadine El Ghrissi, G. Zaccai, Martin Grininger, Wilhelm Maximilian Hützler, Ronnald Vollrath, Estelle Mossou, Miriam Kohagen, Dieter Oesterhelt
Publikováno v:
CrystEngComm. 22:169-172
The crystalline dihydrate of the compatible solute ectoine undergoes a loss of water at ambient conditions and transforms into a highly hygroscopic anhydrate form. This unexpected transition is studied combining single-crystal and powder X-ray, singl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8c333915eac00cffd5457f7df4a95e28
https://doi.org/10.1039/c9ce01599j
https://doi.org/10.1039/c9ce01599j
Autor:
Ronnald Vollrath, Peter Kötter, Martin Grininger, Janet Vonck, Kosta Konstantinidis, Mirko Joppe, Barbara Mulinacci, Manuel Fischer, Luciano Ciccarelli, Dieter Oesterhelt
Publikováno v:
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-13 (2020)
Scientific Reports, Vol 10, Iss 1, Pp 1-13 (2020)
The yeast fatty acid synthase (FAS) is a barrel-shaped 2.6 MDa complex. Upon barrel-formation, two multidomain subunits, each more than 200 kDa large, intertwine to form a heterododecameric complex that buries 170,000 Å2 of protein surface. In spite
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::206acd03fa8a1dfef0963d1d35215783
http://publikationen.ub.uni-frankfurt.de/frontdoor/index/index/docId/53111
http://publikationen.ub.uni-frankfurt.de/frontdoor/index/index/docId/53111
Autor:
J. Rajan Prabu, Christy R. Grace, Jan-Michael Peters, David Haselbach, Elizaveta T. Kulko, Iain F. Davidson, Nicholas G. Brown, Shanshan Yu, Ronnald Vollrath, Sachdev S. Sidhu, Wei Zhang, Edmond R. Watson, Holger Stark, Brenda A. Schulman, Derek L. Bolhuis, Darcie J. Miller
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Ubiquitin (Ub)-mediated proteolysis is a fundamental mechanism used by eukaryotic cells to maintain homeostasis and protein quality, and to control timing in biological processes. Two essential aspects of Ub regulation are conjugation through E1-E2-E
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9451de71e8503ad8bddf23836330d1ce
https://hdl.handle.net/21.11116/0000-0004-584B-621.11116/0000-0004-9A2C-E21.11116/0000-0004-9A2D-D
https://hdl.handle.net/21.11116/0000-0004-584B-621.11116/0000-0004-9A2C-E21.11116/0000-0004-9A2D-D
Autor:
J. Rajan Prabu, Brenda A. Schulman, Elizaveta T. Kulko, Holger Stark, Wei Zhang, David Haselbach, Nicholas G. Brown, Sachdev S. Sidhu, Jan-Michael Peters, Iain F. Davidson, Darcie J. Miller, Shanshan Yu, Ronnald Vollrath, Christy R. Grace, Edmond R. Watson, Derek L. Bolhuis
Ubiquitin-mediated proteolysis is a fundamental mechanism used by eukaryotic cells to maintain homeostasis and protein quality, and to control timing in biological processes. Two essential aspects of ubiquitin regulation are conjugation through E1-E2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4948435905bb92610f707adc79cd6d33
Autor:
Mirko Joppe, Manuel Fischer, Kosta Konstantinidis, Janet Vonck, Luciano Ciccarelli, Dieter Oesterhelt, Ronnald Vollrath, Peter Kötter, Barbara Mulinacci, Martin Grininger
The fungal fatty acid synthase (fFAS) multienzyme is a barrel-shaped 2.6 MDa complex comprising six times eight catalytic domains. Upon barrel-formation, up to several hundred kDa large polypeptides intertwine to bury about 170,000 Å2of protein surf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2bd9f063c17fa733d1b00d62b247300
https://doi.org/10.1101/336578
https://doi.org/10.1101/336578
Autor:
Barbara Mulinacci, Martin Grininger, Ronnald Vollrath, Caecilia Koestler, Dieter Oesterhelt, Patrik Johansson
Publikováno v:
Structure. 17(8):1063-1074
SummaryThe fungal type I fatty acid synthase (FAS) is a 2.6 MDa multienzyme complex, catalyzing all necessary steps for the synthesis of long acyl chains. To be catalytically competent, the FAS must be activated by a posttranslational modification of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55510b39a4825d86e94722912666d9da
Autor:
Patrik Johansson, Dieter Oesterhelt, Andy Wende, Martin Grininger, Michael L. Dyall-Smith, Ronnald Vollrath
Publikováno v:
Journal of molecular biology. 400(1)
Phosphate is an essential component of all cells that must be taken up from the environment. Prokaryotes commonly secrete alkaline phosphatases (APs) to recruit phosphate from organic compounds by hydrolysis. In this study, the AP from Halobacterium
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c805dd7a57edec6453355c0a32e17d2a
https://pubmed.ncbi.nlm.nih.gov/20438737
https://pubmed.ncbi.nlm.nih.gov/20438737