Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Ronja Seibel"'
Autor:
Corinna Schmidt, Gregor Wille, Ronja Seibel, Markus Fischer, Aline Zimmer, Maria Wehsling, Maxime Le Mignon
Publikováno v:
Journal of Biotechnology. 321:1-12
Highly concentrated cell culture media formulations are essential to develop next generation bioprocesses used to produce therapeutic monoclonal antibodies, fusion proteins, bispecific molecules and mAb fragments. Although cysteine/cystine and tyrosi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0e2fd1ac89e9e3896edf89cee04a29b
https://doi.org/10.1016/j.jbiotec.2020.06.013
https://doi.org/10.1016/j.jbiotec.2020.06.013
Autor:
Sandra Maier, Susanne Bohl, Maria Wehsling, Anne Zeck, Ronja Seibel, Alisa Schnellbaecher, Aline Zimmer
Publikováno v:
mAbs. 9:889-897
The quality of recombinant proteins such as monoclonal antibodies produced using Chinese hamster ovary cell-based mammalian systems is dependent on many factors, including cell line, process and cell culture media. Due to these factors, the generated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce697066f477b9009adee1b2aa28c063
https://doi.org/10.1080/19420862.2017.1333212
https://doi.org/10.1080/19420862.2017.1333212
Autor:
Caroline Hecklau, Sascha Pering, Joerg von Hagen, Thomas Eichhorn, Alisa Schnellbaecher, Aline Zimmer, Maria Wehsling, Ronja Seibel
Publikováno v:
Journal of Biotechnology. 218:53-63
Industrial fed-batch cultivation of mammalian cells is used for the production of therapeutic proteins such as monoclonal antibodies. Besides medium ensuring initial growth, feeding is necessary to improve growth, viability and antibody production. E
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c071faec1896ab74de859152c79e12d0
https://doi.org/10.1016/j.jbiotec.2015.11.022
https://doi.org/10.1016/j.jbiotec.2015.11.022
Publikováno v:
BMC Proceedings
Background Mammalian fed-batch processes for monoclonal antibody (mAb) production rely on strategic feeding of several nutrients such as glucose, vitamins and amino acids to extend culture time and improve protein production [1]. In actual processes,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd8d6587d6439d8d5f955dfd3152e72f
https://doi.org/10.1186/1753-6561-9-s9-p55
https://doi.org/10.1186/1753-6561-9-s9-p55