The zebrafish mutantlbk/vam6resembles human multisystemic disorders caused by aberrant trafficking of endosomal vesicles

Autor: Oliver Biehlmaier, Yuri V. Makhankov, Heinz Schwarz, Helia B. Schonthaler, Oliver Rinner, Robert Geisler, Stephan C.F. Neuhauss, Ralf Dahm, Valerie C. Fleisch, Ronja Bahadori

Publikováno v: Development. 135:387-399

The trafficking of intracellular vesicles is essential for a number of cellular processes and defects in this process have been implicated in a wide range of human diseases. We identify the zebrafish mutant lbk as a novel model for such disorders. lb

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed376472db25a603c403a1ea6949817a
https://doi.org/10.1242/dev.006098

Retinal function and morphology in two zebrafish models of oculo-renal syndromes

Autor: Silke Geiger-Rudolph, Oliver Rinner, Ronja Bahadori, Robert Geisler, Mathias W. Seeliger, Matthias Huber, Stephan C.F. Neuhauss

Publikováno v: The European journal of neuroscience. 18(6)

We characterized visual system defects in two recessive zebrafish mutants oval and elipsa. These mutants share the syndromic phenotype of outer retinal dystrophy in conjunction with cystic renal disorder. We tested the function of the larval visual s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc4edb982de9d52f1446cff1a9a1f746
https://pubmed.ncbi.nlm.nih.gov/14511318

The Zebrafishfade outMutant: A Novel Genetic Model for Hermansky–Pudlak Syndrome

Autor: Oliver Biehlmaier, Oliver Rinner, Yuri V. Makhankov, Prashanth Rao, Stephan C.F. Neuhauss, Helia B. Schonthaler, Pudur Jagadeeswaran, Ronja Bahadori

Publikováno v: Investigative Opthalmology & Visual Science. 47:4523

PURPOSE: To characterize retinal morphology and visual system function in the zebrafish mutant fade out (fad) and to establish the mutant as a lower vertebrate model for Hermansky-Pudlak syndrome (HPS). METHODS: Retinal morphology of fad larvae was e

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dcc9357f348677f4bdb0cc971c5e98b9
https://doi.org/10.1167/iovs.05-1596

Modafinil for the treatment of fatigue in lung cancer: results of a placebo-controlled, double-blind, randomized trial.

Autor: Spathis A; Anna Spathis and Kate Fife, Cambridge University Hospitals National Health Service (NHS) Foundation Trust, Cambridge; Fiona Blackhall, The Christie NHS Foundation Trust and University of Manchester, Manchester; Susan Dutton, Ronja Bahadori, Rose Wharton, and Bee Wee, University of Oxford; Bee Wee, Sir Michael Sobell House, Oxford; Mary O'Brien, Royal Marsden Hospital; Patrick Stone, St George's University of London; Tim Benepal, St George's Hospital NHS Trust, London; and Nick Bates, Buckinghamshire Healthcare NHS Trust, Aylesbury, United Kingdom. aspathis@doctors.org.uk., Fife K; Anna Spathis and Kate Fife, Cambridge University Hospitals National Health Service (NHS) Foundation Trust, Cambridge; Fiona Blackhall, The Christie NHS Foundation Trust and University of Manchester, Manchester; Susan Dutton, Ronja Bahadori, Rose Wharton, and Bee Wee, University of Oxford; Bee Wee, Sir Michael Sobell House, Oxford; Mary O'Brien, Royal Marsden Hospital; Patrick Stone, St George's University of London; Tim Benepal, St George's Hospital NHS Trust, London; and Nick Bates, Buckinghamshire Healthcare NHS Trust, Aylesbury, United Kingdom., Blackhall F; Anna Spathis and Kate Fife, Cambridge University Hospitals National Health Service (NHS) Foundation Trust, Cambridge; Fiona Blackhall, The Christie NHS Foundation Trust and University of Manchester, Manchester; Susan Dutton, Ronja Bahadori, Rose Wharton, and Bee Wee, University of Oxford; Bee Wee, Sir Michael Sobell House, Oxford; Mary O'Brien, Royal Marsden Hospital; Patrick Stone, St George's University of London; Tim Benepal, St George's Hospital NHS Trust, London; and Nick Bates, Buckinghamshire Healthcare NHS Trust, Aylesbury, United Kingdom., Dutton S; Anna Spathis and Kate Fife, Cambridge University Hospitals National Health Service (NHS) Foundation Trust, Cambridge; Fiona Blackhall, The Christie NHS Foundation Trust and University of Manchester, Manchester; Susan Dutton, Ronja Bahadori, Rose Wharton, and Bee Wee, University of Oxford; Bee Wee, Sir Michael Sobell House, Oxford; Mary O'Brien, Royal Marsden Hospital; Patrick Stone, St George's University of London; Tim Benepal, St George's Hospital NHS Trust, London; and Nick Bates, Buckinghamshire Healthcare NHS Trust, Aylesbury, United Kingdom., Bahadori R; Anna Spathis and Kate Fife, Cambridge University Hospitals National Health Service (NHS) Foundation Trust, Cambridge; Fiona Blackhall, The Christie NHS Foundation Trust and University of Manchester, Manchester; Susan Dutton, Ronja Bahadori, Rose Wharton, and Bee Wee, University of Oxford; Bee Wee, Sir Michael Sobell House, Oxford; Mary O'Brien, Royal Marsden Hospital; Patrick Stone, St George's University of London; Tim Benepal, St George's Hospital NHS Trust, London; and Nick Bates, Buckinghamshire Healthcare NHS Trust, Aylesbury, United Kingdom., Wharton R; Anna Spathis and Kate Fife, Cambridge University Hospitals National Health Service (NHS) Foundation Trust, Cambridge; Fiona Blackhall, The Christie NHS Foundation Trust and University of Manchester, Manchester; Susan Dutton, Ronja Bahadori, Rose Wharton, and Bee Wee, University of Oxford; Bee Wee, Sir Michael Sobell House, Oxford; Mary O'Brien, Royal Marsden Hospital; Patrick Stone, St George's University of London; Tim Benepal, St George's Hospital NHS Trust, London; and Nick Bates, Buckinghamshire Healthcare NHS Trust, Aylesbury, United Kingdom., O'Brien M; Anna Spathis and Kate Fife, Cambridge University Hospitals National Health Service (NHS) Foundation Trust, Cambridge; Fiona Blackhall, The Christie NHS Foundation Trust and University of Manchester, Manchester; Susan Dutton, Ronja Bahadori, Rose Wharton, and Bee Wee, University of Oxford; Bee Wee, Sir Michael Sobell House, Oxford; Mary O'Brien, Royal Marsden Hospital; Patrick Stone, St George's University of London; Tim Benepal, St George's Hospital NHS Trust, London; and Nick Bates, Buckinghamshire Healthcare NHS Trust, Aylesbury, United Kingdom., Stone P; Anna Spathis and Kate Fife, Cambridge University Hospitals National Health Service (NHS) Foundation Trust, Cambridge; Fiona Blackhall, The Christie NHS Foundation Trust and University of Manchester, Manchester; Susan Dutton, Ronja Bahadori, Rose Wharton, and Bee Wee, University of Oxford; Bee Wee, Sir Michael Sobell House, Oxford; Mary O'Brien, Royal Marsden Hospital; Patrick Stone, St George's University of London; Tim Benepal, St George's Hospital NHS Trust, London; and Nick Bates, Buckinghamshire Healthcare NHS Trust, Aylesbury, United Kingdom., Benepal T; Anna Spathis and Kate Fife, Cambridge University Hospitals National Health Service (NHS) Foundation Trust, Cambridge; Fiona Blackhall, The Christie NHS Foundation Trust and University of Manchester, Manchester; Susan Dutton, Ronja Bahadori, Rose Wharton, and Bee Wee, University of Oxford; Bee Wee, Sir Michael Sobell House, Oxford; Mary O'Brien, Royal Marsden Hospital; Patrick Stone, St George's University of London; Tim Benepal, St George's Hospital NHS Trust, London; and Nick Bates, Buckinghamshire Healthcare NHS Trust, Aylesbury, United Kingdom., Bates N; Anna Spathis and Kate Fife, Cambridge University Hospitals National Health Service (NHS) Foundation Trust, Cambridge; Fiona Blackhall, The Christie NHS Foundation Trust and University of Manchester, Manchester; Susan Dutton, Ronja Bahadori, Rose Wharton, and Bee Wee, University of Oxford; Bee Wee, Sir Michael Sobell House, Oxford; Mary O'Brien, Royal Marsden Hospital; Patrick Stone, St George's University of London; Tim Benepal, St George's Hospital NHS Trust, London; and Nick Bates, Buckinghamshire Healthcare NHS Trust, Aylesbury, United Kingdom., Wee B; Anna Spathis and Kate Fife, Cambridge University Hospitals National Health Service (NHS) Foundation Trust, Cambridge; Fiona Blackhall, The Christie NHS Foundation Trust and University of Manchester, Manchester; Susan Dutton, Ronja Bahadori, Rose Wharton, and Bee Wee, University of Oxford; Bee Wee, Sir Michael Sobell House, Oxford; Mary O'Brien, Royal Marsden Hospital; Patrick Stone, St George's University of London; Tim Benepal, St George's Hospital NHS Trust, London; and Nick Bates, Buckinghamshire Healthcare NHS Trust, Aylesbury, United Kingdom.

Publikováno v: Journal of clinical oncology : official journal of the American Society of Clinical Oncology [J Clin Oncol] 2014 Jun 20; Vol. 32 (18), pp. 1882-8. Date of Electronic Publication: 2014 Apr 28.