Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Ronit Mor-Cohen"'
Autor:
Freda Passam, Joyce Chiu, Lining Ju, Aster Pijning, Zeenat Jahan, Ronit Mor-Cohen, Adva Yeheskel, Katra Kolšek, Lena Thärichen, Camilo Aponte-Santamaría, Frauke Gräter, Philip J Hogg
Publikováno v:
eLife, Vol 7 (2018)
How proteins harness mechanical force to control function is a significant biological question. Here we describe a human cell surface receptor that couples ligand binding and force to trigger a chemical event which controls the adhesive properties of
Externí odkaz:
https://doaj.org/article/cb9308714c6048dea975537d7c8c7c92
Purpose Activating somatic mutations in ubiquitin-specific protease-8 (USP8), encoding a deubiquitinating protein, are found in approximately 30% of corticotroph-derived pituitary adenomas (CPA). USP8 has immunomodulating properties that were demonst
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eb14523c42331eb6a29bc038646500fd
https://doi.org/10.21203/rs.3.rs-372059/v1
https://doi.org/10.21203/rs.3.rs-372059/v1
Autor:
Yair Neuman, Shiraz Gefen-Halevi, Avi Epstein, Gad Segal, Ya’ara Gutman, Noya Shilo, Amit Tirosh, Asaf Biber, Itzchak Levy, Galia Rahav, Dan Assaf, Sharon Amit, Ronit Mor-Cohen
Publikováno v:
Internal and Emergency Medicine
Among patients with Coronavirus disease (COVID-19), the ability to identify patients at risk for deterioration during their hospital stay is essential for effective patient allocation and management. To predict patient risk for critical COVID-19 base
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d1f91637c2675cd717afd465b5c89bb
Autor:
Ronit Mor-Cohen, Dhaval Patel, Xavier M. Keutgen, Electron Kebebew, Yuelin Jack Zhu, Naris Nilubol, J. Keith Killian, Amit Tirosh, Jennifer Walling, Vladimir Neychev, Holly S. Stevenson, David Petersen, Paul S. Meltzer
Publikováno v:
Endocr Pract
Objective: To report the rate of candidate actionable somatic mutations in patients with locally advanced and metastatic gastro-enteropancreatic (GEP) neuroendocrine tumors (NET) and of other genetic alterations that may be associated with tumorigene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f047f28f3a06ce36d3beee8ad74cc32
https://europepmc.org/articles/PMC8170837/
https://europepmc.org/articles/PMC8170837/
Autor:
Uri Seligsohn, Antoinette Blair, Matthew T. Rondina, Michal Zucker, Ronit Mor-Cohen, Colin K. Grissom, Robert A. Campbell, Samuel M. Brown
Publikováno v:
Journal of thrombosis and thrombolysis. 47(2)
BACKGROUND. Coagulation Factor XI (FXI) contributes to the pathobiology of sepsis-associated thrombosis and is a target for new therapeutics. Through cleavage of disulfide bonds, FXI becomes reduced (rFXI), accelerating intrinsic coagulation cascade
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b00f0ac776cf9ab5f6093f1f5ffe46a9
https://pubmed.ncbi.nlm.nih.gov/30600428
https://pubmed.ncbi.nlm.nih.gov/30600428
Autor:
Oded Hess, Olga Romanenco, Vera Hazan Sheptovitsky, Ronit Mor-Cohen, Judith Lahav, Nurit Rosenberg
Publikováno v:
Experimental cell research. 381(1)
Cell adhesion to extracellular matrix, mediated by integrin receptors, is crucial for cell survival. Receptor-ligand interaction involves conformational changes in the integrin by a mechanism not fully elucidated. In addition to several direct eviden
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ffcd026511164feccfbf2d3135b99b02
https://pubmed.ncbi.nlm.nih.gov/31042499
https://pubmed.ncbi.nlm.nih.gov/31042499
Autor:
Philip J. Hogg, Freda Passam, Aster E. Pijning, Zeenat Jahan, Joyce Chiu, Lena Thärichen, Katra Kolšek, Camilo Aponte-Santamaría, Ronit Mor-Cohen, Frauke Gräter, Adva Yeheskel, Lining Ju
Publikováno v:
eLife, Vol 7 (2018)
eLife
eLife
How proteins harness mechanical force to control function is a significant biological question. Here we describe a human cell surface receptor that couples ligand binding and force to trigger a chemical event which controls the adhesive properties of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abc0aa1f0f6502e7860979134d7e4bd9
https://doi.org/10.7554/elife.34843
https://doi.org/10.7554/elife.34843
Autor:
Aster E. Pijning, Zeenat Jahan, Lena Thärichen, Ronit Mor-Cohen, Philip J. Hogg, Adva Yeheskel, Joyce Chiu, Freda Passam, Katra Kolšek, Lining Ju, Camilo Aponte-Santamaría, Frauke Gräter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::826643d066dd1a5ba6831c148f9da31e
https://doi.org/10.7554/elife.34843.021
https://doi.org/10.7554/elife.34843.021
Publikováno v:
Journal of thrombosis and haemostasis : JTH. 14(11)
Essentials Reduction of three disulfide bonds in factor (F) XI enhances chromogenic substrate cleavage. We measured FXI activity upon reduction and identified a bond involved in the enhanced activity. Reduction of FXI augments FIX cleavage, probably
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4844d4f685e2e805a83fd6dcb51e49b4
https://pubmed.ncbi.nlm.nih.gov/27575053
https://pubmed.ncbi.nlm.nih.gov/27575053
Autor:
Meytal Landau, Uri Seligsohn, Yulia Einav, Wissam Mansour, Yulia Averbukh, Nurit Rosenberg, Ronit Mor-Cohen, Ehud Zelzion
Publikováno v:
Journal of Biological Chemistry. 287:8879-8891
The β3 subunit of αIIbβ3 and αvβ3 integrins contains four epidermal growth factor (EGF)-like domains. Each domain harbors four disulfide bonds of which one is unique for integrins. We previously discerned a regulatory role of the EGF-4 Cys-560-C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8d0b572c0b41ee63c8020ee61093e99
https://doi.org/10.1074/jbc.m111.311043
https://doi.org/10.1074/jbc.m111.311043