Zobrazeno 1 - 10
of 104
pro vyhledávání: '"Ronit Freeman"'
Autor:
Stephen J. Klawa, Michelle Lee, Kyle D. Riker, Tengyue Jian, Qunzhao Wang, Yuan Gao, Margaret L. Daly, Shreeya Bhonge, W. Seth Childers, Tolulope O. Omosun, Anil K. Mehta, David G. Lynn, Ronit Freeman
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract In neurodegenerative diseases, polymorphism and supramolecular assembly of β-sheet amyloids are implicated in many different etiologies and may adopt either a left- or right-handed supramolecular chirality. Yet, the underlying principles of
Externí odkaz:
https://doaj.org/article/6511971a5a27462aa4ef6f1dc86b0364
Autor:
Sang Hoon Kim, Fiona L. Kearns, Mia A. Rosenfeld, Lorenzo Casalino, Micah J. Papanikolas, Carlos Simmerling, Rommie E. Amaro, Ronit Freeman
Publikováno v:
ACS Central Science, Vol 8, Iss 1, Pp 22-42 (2021)
Externí odkaz:
https://doaj.org/article/e3faa08be0d846a991916496b85dfe31
Autor:
Ronit Freeman, Nicholas Stephanopoulos, Zaida Álvarez, Jacob A Lewis, Shantanu Sur, Chris M Serrano, Job Boekhoven, Sungsoo S. Lee, Samuel I. Stupp
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-11 (2017)
The extracellular matrix can affect cell behaviour both physically and biochemically. Here, the authors developed a substrate that is based on peptides and nucleic acids hybrids that can dynamically present signals upon demand which regulate cell adh
Externí odkaz:
https://doaj.org/article/adec0b74d8f044eba6a16b4902f1965a
Publikováno v:
Sensors, Vol 11, Iss 11, Pp 10388-10397 (2011)
A hybrid consisting of glucose oxidase-functionalized with hemin/G-quadruplex units is used for the chemiluminescence detection of glucose. The glucose oxidase-mediated oxidation of glucose yields gluconic acid and H2O2. The latter in the presence of
Externí odkaz:
https://doaj.org/article/83d7bd678ff34c36889f4c4815a575e8
Autor:
Matthew R. Markovetz, Ian C. Garbarine, Cameron B. Morrison, William J. Kissner, Ian Seim, M. Gregory Forest, Micah J. Papanikolas, Ronit Freeman, Agathe Ceppe, Andrew Ghio, Neil E. Alexis, Stephen M. Stick, Camille Ehre, Richard C. Boucher, Charles R. Esther, Marianne S. Muhlebach, David B. Hill
Publikováno v:
Journal of Cystic Fibrosis. 21:959-966
Mucus hyperconcentration in cystic fibrosis (CF) lung disease is marked by increases in both mucin and DNA concentration. Additionally, it has been shown that half of the mucins present in bronchial alveolar lavage fluid (BALF) from preschool-aged CF
Autor:
Alex Buchberger, Kyle Riker, Julio Bernal-Chanchavac, Raghu Pradeep Narayanan, Chad R. Simmons, Nour Eddine Fahmi, Ronit Freeman, Nicholas Stephanopoulos
Publikováno v:
ACS Applied Bio Materials. 5:4625-4634
Autor:
Sang Hoon Kim, Fiona L. Kearns, Mia A. Rosenfeld, Lane Votapka, Lorenzo Casalino, Micah Papanikolas, Rommie E. Amaro, Ronit Freeman
Publikováno v:
Cell reports. Physical science, vol 4, iss 4
Viral variants of concern continue to arise for SARS-CoV-2, potentially impacting both methods for detection and mechanisms of action. Here, we investigate the effect of an evolving spike positive charge in SARS-CoV-2 variants and subsequent interact
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3eedcc4b21f9052dffb6f6b14135ff3
https://escholarship.org/uc/item/6986n34w
https://escholarship.org/uc/item/6986n34w
Autor:
Ronit Freeman, Samuel I. Stupp, Jacob A. Lewis, Jacqueline M. Godbe, Ivan R. Sasselli, M. Hussain Sangji
Publikováno v:
Acta Biomaterialia. 135:87-99
Peptide amphiphiles (PAs) are a class of molecules comprised of short amino acid sequences conjugated to hydrophobic moieties that may exhibit self-assembly in water into supramolecular structures. We investigate here how mechanical properties of hyd
Autor:
Richard C. Boucher, Micah J. Papanikolas, Mark Gregory Forest, David B. Hill, Takafumi Kato, Xue-Zheng Cao, Matthew R. Markovetz, Andrew G. Ford, Ronit Freeman
Publikováno v:
Stud Appl Math
We develop the first molecular dynamics model of airway mucus based on the detailed physical properties and chemical structure of the predominant gel-forming mucin MUC5B. Our airway mucus model leverages the LAMMPS open-source code [https://lammps.sa
Autor:
Sang Hoon Kim, Fiona L. Kearns, Mia A. Rosenfeld, Lane Votapka, Lorenzo Casalino, Micah Papanikolas, Rommie E. Amaro, Ronit Freeman
The SARS-CoV-2 Omicron sub-lineage contains a significant number of mutations in the spike protein relative to earlier SARS-CoV-2 variants. Most notably, these mutations significantly increased the positive charge of the spike protein that is postula
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cef8cccaaed1c0a08c57e80ffb62a584
https://doi.org/10.26434/chemrxiv-2022-dmqq3
https://doi.org/10.26434/chemrxiv-2022-dmqq3