Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Roni Sarel-Gallily"'
Autor:
Tayma Handal, Sarah Juster, Manar Abu Diab, Shira Yanovsky-Dagan, Fouad Zahdeh, Uria Aviel, Roni Sarel-Gallily, Shir Michael, Ester Bnaya, Shulamit Sebban, Yosef Buganim, Yotam Drier, Vincent Mouly, Stefan Kubicek, Walther J. A. A. van den Broek, Derick G. Wansink, Silvina Epsztejn-Litman, Rachel Eiges
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract Epigenetic defects caused by hereditary or de novo mutations are implicated in various human diseases. It remains uncertain whether correcting the underlying mutation can reverse these defects in patient cells. Here we show by the analysis o
Externí odkaz:
https://doaj.org/article/f2f26f7be8be43019350e3bc09541979
Autor:
Roni Sarel-Gallily, Nissim Benvenisty
Publikováno v:
Cells, Vol 11, Iss 11, p 1729 (2022)
X chromosome inactivation is a mammalian dosage compensation mechanism, where one of two X chromosomes is randomly inactivated in female cells. Previous studies have suggested that primed human embryonic stem cells (hESCs) maintain an eroded state of
Externí odkaz:
https://doaj.org/article/0a774c9feb034610a847d43d2a98c4f1
Publikováno v:
Stem Cell Reports. 18:817-828
Autor:
Roni Sarel-Gallily, Dan Vershkov
Publikováno v:
Frontiers for Young Minds. 10
Have you ever wondered how scientists investigate human diseases and develop treatments to improve human health? For many years, the main way to do so was to use research animals. Animal studies have greatly improved our understanding of human diseas
Publikováno v:
Cell Reports. 38:110573
Haploinsufficiency describes a phenomenon where one functioning allele is insufficient for a normal phenotype, underlying several human diseases. The effect of haploinsufficiency on human embryonic stem cells (hESC) has not been thoroughly studied. T