Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Roni Nitzan-Koren"'
Autor:
Adele Goldman-Pinkovich, Sriram Kannan, Roni Nitzan-Koren, Madhu Puri, Harsh Pawar, Yael Bar-Avraham, Jacquelyn McDonald, Aakash Sur, Wen-Wei Zhang, Greg Matlashewski, Rentala Madhubala, Shulamit Michaeli, Peter J. Myler, Dan Zilberstein
Publikováno v:
mBio, Vol 11, Iss 5 (2020)
ABSTRACT Arginine homeostasis in lysosomes is critical for the growth and metabolism of mammalian cells. Phagolysosomes of macrophages are the niche where the parasitic protozoan Leishmania resides and causes human leishmaniasis. During infection, pa
Externí odkaz:
https://doaj.org/article/0e194efdd6f54cbbaf5c38700237ad61
Autor:
Renana Fischer Weinberger, Sabine Bachmaier, Veronica Ober, George B Githure, Ramu Dandugudumula, Isabelle Q Phan, Michal Almoznino, Eleni Polatoglou, Polina Tsigankov, Roni Nitzan Koren, Peter J Myler, Michael Boshart, Dan Zilberstein
Publikováno v:
PLoS Pathogens, Vol 20, Iss 3, p e1012073 (2024)
Parasitic protozoa of the genus Leishmania cycle between the phagolysosome of mammalian macrophages, where they reside as rounded intracellular amastigotes, and the midgut of female sand flies, which they colonize as elongated extracellular promastig
Externí odkaz:
https://doaj.org/article/4b7f13f047be429aaed3b8bd9b177a11
Autor:
Deninson Alejandro Vargas, David J. Gregory, Roni Nitzan Koren, Dan Zilberstein, Ashton Trey Belew, Najib M. El-Sayed, María Adelaida Gómez
Publikováno v:
Frontiers in Parasitology, Vol 2 (2023)
Host cell functions that participate in the pharmacokinetics and pharmacodynamics (PK/PD) of drugs against intracellular pathogen infections are critical for drug efficacy. In this study, we investigated whether macrophage mechanisms of xenobiotic de
Externí odkaz:
https://doaj.org/article/3a3e86c308f74579b3e15cd09ab1ca59
Autor:
Greg Matlashewski, Madhu Puri, Adele Goldman-Pinkovich, Rentala Madhubala, Yael Bar-Avraham, Dan Zilberstein, Wen-Wei Zhang, Jacquelyn R McDonald, Sriram Kannan, Peter J. Myler, Harsh Pawar, Roni Nitzan-Koren, Shulamit Michaeli, Aakash Sur
Publikováno v:
mBio, Vol 11, Iss 5 (2020)
Arginine homeostasis in lysosomes is critical for the growth and metabolism of mammalian cells. Phagolysosomes of macrophages are the niche where the parasitic protozoan Leishmania resides and causes human leishmaniasis. During infection, parasites e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b2cb91b4e2954e624945f8a22e6d149
https://journals.asm.org/doi/10.1128/mBio.02023-20
https://journals.asm.org/doi/10.1128/mBio.02023-20
Autor:
Peter J. Myler, Jacqueline A. McDonald, Rentala Madhubala, Adele Goldman-Pinkovich, Sriram Kannan, Yael Bar-Avraham, Wen-Wei Zhang, Greg Matlashewski, Madhu Puri, Aakash Sur, Dan Zilberstein, Shulamit Michaeli, Roni Nitzan-Koren
Arginine homeostasis in lysosomes is critical for growth and metabolism of mammalian cells. They employ a specific sensor (SLC38A9) that monitors intra-lysosome arginine sufficiency and subsequently up-regulates cellular mTORC1 activity. Lysosomes of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b40d63b665a8c9fa0fb358cc0c176556
Publikováno v:
International Journal of Applied Science - Research and Review.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b8ff7a88c77e53217987361c61e9e56d
https://doi.org/10.21767/2394-9988-c2-005
https://doi.org/10.21767/2394-9988-c2-005