Regulation of soluble neuropilin 1, an endogenous angiogenesis inhibitor, in liver development and regeneration

Autor: Christiane J. Bruns, Diane R. Bielenberg, Roni Mamluk, Patricia A. D'Amore, Dipak Panigrahy, Michael Klagsbrun, Irit Adini, Nicholas Levonyak

Publikováno v: Pathology. 46:416-423

Neuropilin-1 (NRP1) is a receptor for vascular endothelial growth factor (VEGF). A soluble isoform of Nrp1 (sNrp1) has not been described in the mouse. Our goal was to examine the expression of mouse sNrp1 during liver development and regeneration. s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53128a01dec5292b05c508e4b9462017
https://doi.org/10.1097/pat.0000000000000121

Safety and efficacy of oral octreotide in acromegaly: results of a multicenter phase III trial

Autor: Roni Mamluk, Marcello D. Bronstein, Márta Korbonits, Moisés Mercado, Irit Gliko-Kabir, Károly Rácz, Andrea Giustina, Shlomo Melmed, Asi Haviv, Emese Mezosi, Vera Popovic, Marek Bolanowski, Yona Greenman, Miklós Góth, David L. Kleinberg, Ilan Shimon, Peter J Trainer, Jochen Schopohl, Christian J. Strasburger, Sam Teichman, Nienke R. Biermasz, Benjamin Glaser, Martin Bidlingmaier, Mihail Coculescu, Aart Jan van der Lely

Publikováno v: Journal of Clinical Endocrinology and Metabolism, 100(4), 1699-1708
Journal of Clinical Endocrinology and Metabolism, 100(4), 1699-1708. Endocrine Society

Background: A novel oral octreotide formulation was tested for efficacy and safety in a phase III, multicenter, open-label, dose-titration, baseline-controlled study in patients with acromegaly. Methods: We enrolled 155 complete or partially controll

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc78f42902e28da21d7318fee23f5e13

Neuropilin-1 Binds Vascular Endothelial Growth Factor 165, Placenta Growth Factor-2, and Heparin via Its b1b2 Domain

Autor: John T. Gallagher, Roni Mamluk, Nijole Gasiunas, Matthew E. Kutcher, Ze'ev Gechtman, Michael Klagsbrun

Publikováno v: Journal of Biological Chemistry. 277:24818-24825

Neuroplin-1 (NRP1), a receptor for vascular endothelial growth factor (VEGF) family members, has three distinct extracellular domains, a1a2, b1b2, and c. To determine the VEGF(165) and placenta growth factor 2 (PlGF-2)-binding sites of NRP1, recombin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce96f4f09fce316466b65c492bad3af5
https://doi.org/10.1074/jbc.m200730200

Hormonal Regulation of Messenger Ribonucleic Acid Expression for Steroidogenic Factor-1, Steroidogenic Acute Regulatory Protein, and Cytochrome P450 Side-Chain Cleavage in Bovine Luteal Cells

Autor: Yafa Greber, Roni Mamluk, Rina Meidan

Publikováno v: Biology of Reproduction. 60:628-634

To examine hormonal regulation of genes pertinent to luteal steroidogenesis, bovine theca and granulosa cells derived from preovulatory follicles were cultured with various combinations of forskolin and insulin. On Day 8 of culture, progesterone prod

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c61227262d80b223638124e182c6724
https://doi.org/10.1095/biolreprod60.3.628

Characterization of Messenger Ribonucleic Acid Expression for Prostaglandin F2α and Luteinizing Hormone Receptors in Various Bovine Luteal Cell Types1

Autor: Rina Meidan, Roni Mamluk, Dong-bao Chen, Yaffa Greber, John S. Davis

Publikováno v: Biology of Reproduction. 58:849-856

LH and prostaglandin F 20 (PGF 20) control the life span and function of the corpus luteum (CL). Nevertheless, identification of the various cell types (steroidogenic and nonsteroidogenic) expressing the receptors for these hormones remains controver

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8ee3dd74608bb4f7e6a3c549a249acf7
https://doi.org/10.1095/biolreprod58.3.849