Zobrazeno 1 - 10
of 119
pro vyhledávání: '"Rongzhen Xu"'
Publikováno v:
ZooKeys, Vol 1204, Iss , Pp 191-198 (2024)
Melanastera sinica He & Burckhardt, sp. nov., a new psylloid species developing on Grewia sp., is described from Hainan, China. It is the first Melanastera species reported from Asia and China, and the second species from the Old World. While New Wor
Externí odkaz:
https://doaj.org/article/09c6004588684f939cd61f07f2afd339
Publikováno v:
Shuiwen dizhi gongcheng dizhi, Vol 50, Iss 6, Pp 204-212 (2023)
The Baiyangdian Lake is located in Xiongan New Area, which has a fragile ecological environment and a shortage of water resources. Lake evaporation is one of the main discharge of the Baiyangdian Lake, and research on lake evaporation is of important
Externí odkaz:
https://doaj.org/article/c5170daa837d4b1f803e98cea985aaf0
An oral triple pill-based cocktail effectively controls acute myeloid leukemia with high translation
Autor:
Mengyuan Li, Shuwen Zheng, Qinyuan Gong, Haifeng Zhuang, Zhaoxing Wu, Ping Wang, Xuzhao Zhang, Rongzhen Xu
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 167, Iss , Pp 115584- (2023)
Acute myeloid leukemia (AML) is a deadly hematological malignancy characterized by oncogenic translational addiction that results in over-proliferation and apoptosis evasion of leukemia cells. Various chemo- and targeted therapies aim to reverse this
Externí odkaz:
https://doaj.org/article/f335aba00b9945eea24b71361adf27d9
Autor:
Jiawei Zhang, Yichao Gan, Hongzhi Li, Jie Yin, Xin He, Liming Lin, Senlin Xu, Zhipeng Fang, Byung-wook Kim, Lina Gao, Lili Ding, Eryun Zhang, Xiaoxiao Ma, Junfeng Li, Ling Li, Yang Xu, David Horne, Rongzhen Xu, Hua Yu, Ying Gu, Wendong Huang
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
CDK2 can drive the proliferation of cancer cells. Here, the authors screened for a non-ATP competitive inhibitor of the CDK2/cylinA complex and find that Homoharringtonine can disrupt the complex and promote the degradation of CDK2.
Externí odkaz:
https://doaj.org/article/ac83cddd29e447fc91fa01e2387d3f72
Autor:
Xuzhao Zhang, Zhaoxing Wu, Yuanyuan Hao, Teng Yu, Xian Li, Yun Liang, Jinfan Li, Liansheng Huang, Yang Xu, Xiuzhen Li, Xiaohua Xu, Weiqin Wang, Genbo Xu, Xiaohong Zhang, Qinghua Lv, Yongming Fang, Rongzhen Xu, Wenbin Qian
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Tumor protein 53 (TP53) mutation predicts an unfavorable prognosis in diffuse large B-cell lymphoma (DLBCL), but the molecular basis for this association remains unclear. In several malignancies, the cytidine deaminase apolipoprotein B mRNA editing e
Externí odkaz:
https://doaj.org/article/f66bfb8e8c114711aa9a183ab98d8bfa
Autor:
Yajuan Rui, Jiaming Su, Si Shen, Ying Hu, Dingbo Huang, Wenwen Zheng, Meng Lou, Yifei Shi, Meng Wang, Shiqi Chen, Na Zhao, Qi Dong, Yong Cai, Rongzhen Xu, Shu Zheng, Xiao-Fang Yu
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 6, Iss 1, Pp 1-11 (2021)
Abstract The emergence of SARS-CoV-2 has resulted in the COVID-19 pandemic, leading to millions of infections and hundreds of thousands of human deaths. The efficient replication and population spread of SARS-CoV-2 indicates an effective evasion of h
Externí odkaz:
https://doaj.org/article/12fe83e7c1b24f868489d91e03ccc5ba
Autor:
Zhaoxing Wu, Haifeng Zhuang, Qingfeng Yu, Xuzhao Zhang, Xudong Jiang, Xiaoya Lu, Ying Xu, Linlin Yang, Bowen Wu, An Ma, Lei Zhang, Xibin Xiao, Yun Liang, Ruilan Gao, Jianping Shen, Rongzhen Xu
Publikováno v:
Translational Oncology, Vol 12, Iss 6, Pp 801-809 (2019)
As a heterogeneous group of clonal disorders, acute myeloid leukemia with internal tandem duplication of fms-like tyrosine kinase 3 (FLT3-ITD) mutation usually shows an inferior prognosis. In the present study, we found that homoharringtonine (HHT),
Externí odkaz:
https://doaj.org/article/50eb55464a5c4aaea816fe50ef184d60
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 133, Iss , Pp 111054- (2021)
Acute myeloid leukemia harboring internal tandem duplication of FMS-like tyrosine kinase 3 (FLT3-ITD AML) is a subset of highly aggressive malignancies with poor clinical outcome. Despite some advances in the development of FLT3 tyrosine kinase inhib
Externí odkaz:
https://doaj.org/article/c2da5646c02c42618c4e1039e3fc1670
Autor:
Qingfeng Yu, Ping Wang, Linlin Yang, Zhaoxing Wu, Shu Li, Ying Xu, Bowen Wu, An Ma, Xiaoxian Gan, Rongzhen Xu
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 117, Iss , Pp - (2019)
Proto-oncogene Myc, a key transcription factor, is frequently deregulated in human leukemia with aggressive and poor clinical outcome, but the development of MYC inhibitors remains challenging due to MYC helix-loop-helix topology lacking druggable do
Externí odkaz:
https://doaj.org/article/00c32fcc034f4436b3bd8511ca8e0fa6
Publikováno v:
Advances in Mechanical Engineering, Vol 9 (2017)
Case-based reasoning has proven to be a promising methodology for obtaining new mechanical products by adapting previous cases. However, case adaptation is still a bottleneck in case-based reasoning. The key issue in case adaptation is acquiring the
Externí odkaz:
https://doaj.org/article/809c539a34d049828dbac9709063b360