Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Rongshuang Huang"'
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 8, Iss 1, Pp 1-20 (2023)
Abstract Chronic kidney disease (CKD) is estimated to affect 10–14% of global population. Kidney fibrosis, characterized by excessive extracellular matrix deposition leading to scarring, is a hallmark manifestation in different progressive CKD; How
Externí odkaz:
https://doaj.org/article/b6e67c8190a3452c8f2ae0cb64800f12
Autor:
Letian Yang, Bo Wang, Fan Guo, Rongshuang Huang, Yan Liang, Lingzhi Li, Sibei Tao, Ting Yin, Ping Fu, Liang Ma
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 7, Iss 1, Pp 1-15 (2022)
Abstract Acute kidney injury (AKI) is a serious clinical complication with high morbidity and mortality rates. Despite substantial progress in understanding the mechanism of AKI, no effective therapy is available for treatment or prevention. We previ
Externí odkaz:
https://doaj.org/article/a3599a0e4e3e4cf3994498bb53745492
Autor:
Weijing Lai, Rongshuang Huang, Bo Wang, Min Shi, Fan Guo, Lingzhi Li, Qian Ren, Sibei Tao, Ping Fu, Liang Ma
Publikováno v:
MedComm, Vol 4, Iss 4, Pp n/a-n/a (2023)
Abstract Although inhibition of neprilysin (NEP) might be a therapeutic strategy with the potential to improve the outcome of chronic kidney disease (CKD), the versatile function of NEP with its mechanism remains obscure in kidney fibrosis. In the st
Externí odkaz:
https://doaj.org/article/eedbca5b66c044599c31b05e99ab083b
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2022)
Natural flavonoid pectolinarigenin (PEC) was reported to alleviate tubulointerstitial fibrosis of unilateral ureteral obstruction (UUO) mice in our previous study. To further investigate nephroprotective effects of PEC in hyperuricemic nephropathy (H
Externí odkaz:
https://doaj.org/article/9dbdbdadfceb451abc3b9d61e1ec2b76
Publikováno v:
Chinese Medical Journal, Vol 135, Iss 2, Pp 245-246 (2022)
Externí odkaz:
https://doaj.org/article/6df77621fde049d0bd7dfe83eb268e98
Autor:
Yanhuan Feng, Fan Guo, Zijing Xia, Jing Liu, Hongxia Mai, Yan Liang, Guonian Zhu, Yanping Li, Lin Bai, Lingzhi Li, Rongshuang Huang, Min Shi, Liang Ma, Ping Fu
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
The macrophage-to-myofibroblast transition (MMT) process is an important pathway that contributing to renal interstitial fibrosis (RIF). Fatty acid–binding protein 4 (FABP4) deteriorated RIF via promoting inflammation in obstructive nephropathy. Ho
Externí odkaz:
https://doaj.org/article/7c8e152bc32d49e584797737982410b1
Autor:
Jing Liu, Xue Cui, Fan Guo, Xinrui Li, Lingzhi Li, Jing Pan, Sibei Tao, Rongshuang Huang, Yanhuan Feng, Liang Ma, Ping Fu
Publikováno v:
PLoS ONE, Vol 14, Iss 10, p e0224158 (2019)
Histone deacetylases 6 (HDAC6) has been reported to be involved in the pathogenesis of rhabdomyolysis-induced acute kidney injury (AKI). Selective inhibition of HDAC6 activity might be a potential treatment for AKI. In our lab, N-hydroxy-6-(4-(methyl
Externí odkaz:
https://doaj.org/article/790cce8a223a427db9e8927c797f59fe
Autor:
Rongshuang Huang, Min Shi, Fan Guo, Yuying Feng, Yanhuan Feng, Jing Liu, Lingzhi Li, Yan Liang, Jin Xiang, Song Lei, Liang Ma, Ping Fu
Publikováno v:
Frontiers in Pharmacology, Vol 9 (2018)
Acute kidney injury (AKI) is a common and potentially life-threatening complication. Studies confirmed that circulating FABP4 depended on renal function of AKI patients. In our previous study, FABP4 was involved in the pathogenesis of I/R-induced AKI
Externí odkaz:
https://doaj.org/article/b1f34655bff34dcb83deafeef44cdee1
Autor:
Yuying Feng, Rongshuang Huang, Fan Guo, Yan Liang, Jin Xiang, Song Lei, Min Shi, Lingzhi Li, Jing Liu, Yanhuan Feng, Liang Ma, Ping Fu
Publikováno v:
Frontiers in Pharmacology, Vol 9 (2018)
Histone deacetylase 6 (HDAC6) contributed to the pathogenesis of rhabdomyolysis-induced acute kidney injury (AKI) and selective inhibition of HDAC6 activity may be a promising strategy for the treatment of AKI. Compound 23BB as a highly selective HDA
Externí odkaz:
https://doaj.org/article/ab2a34628d0545b9b4ff4cf7bf0330db
Publikováno v:
Molecules, Vol 22, Iss 10, p 1683 (2017)
Treatment of septic acute kidney injury (AKI) has still been beyond satisfaction, although anti-inflammatory therapy is beneficial for sepsis-induced AKI. Compound 5b was derived from natural pyranochalcones and exhibited potent anti-inflammatory act
Externí odkaz:
https://doaj.org/article/5ec9c90c34854bd0a4b599b17a48aa29