Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Rongqing Shuang"'
Autor:
Wenning Qin, Rongqing Shuang, Gregory J. Fici, Richard L. Myers, Adele M. Pauley, Chai An Mao, Ismail Kola, Jinhe Li, Carol S Himes, Gregory P. Donoho, Jeffrey S. Nye, Kalpana M. Merchant
Publikováno v:
Journal of Biological Chemistry. 278:33445-33449
Nicastrin is a component of the gamma-secretase complex that has been shown to adhere to presenilin-1 (PS1), Notch, and APP. Here we demonstrate that Nicastrin-deficient mice showed a phenotype that is indistinguishable from PS1/PS2 double knock-out
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::797d2fdb7c28d27a2b593322f6cb603c
https://doi.org/10.1074/jbc.m301288200
https://doi.org/10.1074/jbc.m301288200
Autor:
Jinhe Li, Mark E. Gurney, Allen E. Buhl, Rongqing Shuang, Richard L. Myers, Cara L. Ruble, Riqiang Yan, John R. Brashler, Adele M. Pauley
Publikováno v:
Journal of Neurochemistry. 82:1540-1548
Mutations in the human presenilin genes (PS1 or PS2) have been linked to autosomal dominant, early onset Alzheimer's disease (AD). Presenilins, probably as an essential part of gamma-secretase, modulate gamma-cleavage of the amyloid protein precursor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c33dac825398632884bdfded2824adbc
https://doi.org/10.1046/j.1471-4159.2002.01105.x
https://doi.org/10.1046/j.1471-4159.2002.01105.x
Autor:
Lin Zhang, Angus Fletcher, David R. Giovannucci, Rongqing Shuang, Edward L. Stuenkel, Mary A. Bittner
Publikováno v:
Journal of Biological Chemistry. 274:4027-4035
Munc18a, a mammalian neuronal homologue of Saccharomyces cerevisiae Sec1p protein, is essential for secretion, likely as a result of its high affinity interaction with the target SNARE protein syntaxin 1a (where SNARE is derived from SNAP receptor (t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3e67c5939d397b9b2d063214d10a7b6
https://doi.org/10.1074/jbc.274.7.4027
https://doi.org/10.1074/jbc.274.7.4027
Autor:
Rongqing Shuang, Guy E. Groblewski, Edward L. Stuenkel, Angus Fletcher, Lin Zhang, Jonathan Pevsner
Publikováno v:
Journal of Biological Chemistry. 273:4957-4966
The Munc-18-syntaxin 1A complex has been postulated to act as a negative control on the regulated exocytotic process because its formation blocks the interaction of syntaxin with vesicle SNARE proteins. However, the formation of this complex is simul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1e9ae3edc4f1963e6a29b44c1076206
https://doi.org/10.1074/jbc.273.9.4957
https://doi.org/10.1074/jbc.273.9.4957
Publikováno v:
Neuroendocrinology. 64(5)
Substantial evidence now exists to support a defined complex of interacting proteins, comprised of soluble, vesicle and plasma membrane components, as the core of a general membrane fusion mechanism. Specializations to the general secretory model occ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a3721bd4110e238a1d143f9660132ab
https://pubmed.ncbi.nlm.nih.gov/8930938
https://pubmed.ncbi.nlm.nih.gov/8930938
Autor:
Jinhe Li1 jinhe.li@pfizer.com, Fici, Gregory J.1, Chai-An Mao1, Myers, Richard L.1, Rongqing Shuang1, Donoho, Gregory P.1, Pauley, Adele M.1, Himes, Carol S.1, Wenning Qin1, Ismail Kola1, Merchant, Kalpana M.1, Nye, Jeffrey S.1
Publikováno v:
Journal of Biological Chemistry. 8/29/2003, Vol. 278 Issue 35, p33445-33449. 5p. 1 Color Photograph, 4 Graphs.