Výsledky vyhledávání - "Rongnoparut, P"

Akademický článek

Inhibition of human cytochromes P450 2A6 and 2A13 by flavonoids, acetylenic thiophenes and sesquiterpene lactones from Pluchea indica and Vernonia cinerea

Autor: Supattra Boonruang, Khanistha Prakobsri, Phisit Pouyfung, Ekaruth Srisook, Aruna Prasopthum, Pornpimol Rongnoparut, Songklod Sarapusit

Publikováno v: Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 32, Iss 1, Pp 1136-1142 (2017)

The human liver cytochrome P450 (CYP) 2A6 and the respiratory CYP2A13 enzymes play role in nicotine metabolism and activation of tobacco-specific nitrosamine carcinogens. Inhibition of both enzymes could offer a strategy for smoking abstinence and de

Externí odkaz: https://doaj.org/article/75f09d2a437d4acba2d87cedfbba1e00

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Akademický článek

Distal effect of amino acid substitutions in CYP2C9 polymorphic variants causes differences in interatomic interactions against (S)-warfarin.

Autor: Panida Lertkiatmongkol, Anunchai Assawamakin, George White, Gaurav Chopra, Pornpimol Rongnoparut, Ram Samudrala, Sissades Tongsima

Publikováno v: PLoS ONE, Vol 8, Iss 9, p e74053 (2013)

Cytochrome P450 2C9 (CYP2C9) is crucial in excretion of commonly prescribed drugs. However, changes in metabolic activity caused by CYP2C9 polymorphisms inevitably result in adverse drug effects. CYP2C9*2 and *3 are prevalent in Caucasian populations

Externí odkaz: https://doaj.org/article/b583c5c17ecb45ccb1f8645a180f99eb

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Akademický článek

Correction: Distal Effect of Amino Acid Substitutions in CYP2C9 Polymorphic Variants Causes Differences in Interatomic Interactions against -Warfarin.

Autor: Panida Lertkiatmongkol, Anunchai Assawamakin, George White, Gaurav Chopra, Pornpimol Rongnoparut, Ram Samudrala, Sissades Tongsima

Publikováno v: PLoS ONE, Vol 8, Iss 9 (2013)

Externí odkaz: https://doaj.org/article/2c7e8efe7abb4e0e9f515f3cb61f98e0

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Akademický článek

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Akademický článek

Homology modeling of mosquito cytochrome P450 enzymes involved in pyrethroid metabolism: insights into differences in substrate selectivity

Autor: Rongnoparut Pornpimol, Jenwitheesuk Ekachai, Lertkiatmongkol Panida

Publikováno v: BMC Research Notes, Vol 4, Iss 1, p 321 (2011)

Abstract Background Cytochrome P450 enzymes (P450s) have been implicated in insecticide resistance. Anopheles minumus mosquito P450 isoforms CYP6AA3 and CYP6P7 are capable of metabolizing pyrethroid insecticides, however CYP6P8 lacks activity against

Externí odkaz: https://doaj.org/article/edcfb83e363842fda46f850812841681

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