Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Rongji Chen"'
Autor:
Qiushi Li, Sukanya Ramasamy, Pooja Singh, Jillian M. Hagel, Sonja M. Dunemann, Xue Chen, Rongji Chen, Lisa Yu, Joseph E. Tucker, Peter J. Facchini, Sam Yeaman
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
The opium poppy has been a source of painkilling drugs synthesized by the benzylisoquinoline alkaloid pathway. Here, the authors report an improved genome assembly and reveal gene clustering and copy number variation in alkaloid metabolic pathways.
Externí odkaz:
https://doaj.org/article/e91dc3f830b242d7bc6f05c17604aa7b
Autor:
Qiushi Li, Sukanya Ramasamy, Pooja Singh, Jillian M. Hagel, Sonja M. Dunemann, Xue Chen, Rongji Chen, Lisa Yu, Joseph E. Tucker, Peter J. Facchini, Sam Yeaman
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-1 (2020)
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Externí odkaz:
https://doaj.org/article/6ae5b4573d5441dbbedaf32f39f4198d
Autor:
Yuan Ning, Dhruva Bhattacharya, Richard E. Jones, Fangkun Zhao, Rongji Chen, Jinsong Zhang, Mingwu Wang
Publikováno v:
Journal of Ophthalmology, Vol 2016 (2016)
Purpose. To assess the conjunctival functionality in a rabbit dry eye (DE) model. Methods. Nictitating membrane, lacrimal and Harderian glands were surgically excised from male New Zealand white rabbits using minimally invasive surgery. Fluorescein/r
Externí odkaz:
https://doaj.org/article/b5cf9565b16b4c108528a5c633729098
Autor:
Lisa Yu, Pooja Singh, Sam Yeaman, Sukanya Ramasamy, Joseph Tucker, Jillian M. Hagel, Qiushi Li, Xue Chen, Sonja M. Dunemann, Peter J. Facchini, Rongji Chen
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
Nature Communications
Nature Communications
Genes in plant secondary metabolic pathways enable biosynthesis of a range of medically and industrially important compounds, and are often clustered on chromosomes. Here, we study genomic clustering in the benzylisoquinoline alkaloid (BIA) pathway i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b85284e5d9a9728d2ff612e7bea47cc3
https://doaj.org/article/e91dc3f830b242d7bc6f05c17604aa7b
https://doaj.org/article/e91dc3f830b242d7bc6f05c17604aa7b
Autor:
Rongji Chen, Peter J. Facchini, Mehran Dastmalchi, Limei Chang, Lisa Yu, Jillian M. Hagel, Xue Chen
Publikováno v:
Plant Physiol
Although opiate biosynthesis has been largely elucidated, and cell-to-cell transport has been long postulated, benzylisoquinoline alkaloid (BIA) transporters from opium poppy (Papaver somniferum) have not been reported. Investigation of a purine perm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2690cad4899917a17c2e5e7e5fb2a911
https://doi.org/10.1104/pp.19.00565
https://doi.org/10.1104/pp.19.00565
Autor:
Sukanya Ramasamy, Peter J. Facchini, Limei Chang, Mehran Dastmalchi, Rongji Chen, Sam Yeaman, Jillian M. Hagel, Xue Chen
Publikováno v:
Nature Chemical Biology. 15:384-390
The isomerization of neopinone to codeinone is a critical step in the biosynthesis of opiate alkaloids in opium poppy. Previously assumed to be spontaneous, the process is in fact catalyzed enzymatically by neopinone isomerase (NISO). Without NISO th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1c1f6a85f721a720ef3baa9f60be9d7
https://doi.org/10.1038/s41589-019-0247-0
https://doi.org/10.1038/s41589-019-0247-0
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2172
Virus-induced gene silencing (VIGS) enables the targeted silencing of genes in opium poppy (Papaver somniferum) and has been used extensively to determine or support the physiological functions of benzylisoquinoline alkaloid biosynthetic enzymes. Her
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a4d4587c9fa19bda6ec1c13b4d940cd2
https://pubmed.ncbi.nlm.nih.gov/32557363
https://pubmed.ncbi.nlm.nih.gov/32557363
Autor:
Sukanya Ramasamy, Sam Yeaman, Sonja M. Dunemann, Xue Chen, Peter J. Facchini, Jillian M. Hagel, Lisa Yu, Joseph Tucker, Qiushi Li, Pooja Singh, Rongji Chen
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-1 (2020)
Nature Communications
Nature Communications
Genes in plant secondary metabolic pathways enable biosynthesis of a range of medically and industrially important compounds, and are often clustered on chromosomes. Here, we study genomic clustering in the benzylisoquinoline alkaloid (BIA) pathway i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6884b731fb99bb4695ff1d6ccab4a8fb
https://doi.org/10.1038/s41467-020-16467-3
https://doi.org/10.1038/s41467-020-16467-3
Publikováno v:
Methods in Molecular Biology ISBN: 9781071607503
Virus-induced gene silencing (VIGS) enables the targeted silencing of genes in opium poppy (Papaver somniferum) and has been used extensively to determine or support the physiological functions of benzylisoquinoline alkaloid biosynthetic enzymes. Her
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::abaf83017cbb493a59114f500ebf8094
https://doi.org/10.1007/978-1-0716-0751-0_7
https://doi.org/10.1007/978-1-0716-0751-0_7
Autor:
Steve Zaplachinski, Joseph Boothe, John Teat, J. Christopher Hall, Rongji Chen, Haifeng Wang, Michael D. McLean, Deqiang Yu, Kor-Zheng Mah
Publikováno v:
Transgenic Research. 21:1291-1301
Production of therapeutic monoclonal antibodies using genetically modified plants may provide low cost, high scalability and product safety; however, antibody purification from plants presents a challenge due to the large quantities of biomass that n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74d2101e8d7d9c8a18a726ab6ecee7c6
https://doi.org/10.1007/s11248-012-9603-5
https://doi.org/10.1007/s11248-012-9603-5