Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Ronghui Liang"'
Autor:
Qiaohui Du, Ronghui Liang, Meiling Wu, Minxiao Yang, Yubin Xie, Qing Liu, Kaiming Tang, Xiang Lin, Shuofeng Yuan, Jiangang Shen
Publikováno v:
Journal of Advanced Research, Vol 62, Iss , Pp 273-290 (2024)
Introduction: Emerging severe acute respiratory syndrome (SARS) coronavirus (CoV)-2 causes a global health disaster and pandemic. Seeking effective anti-pan-CoVs drugs benefit critical illness patients of coronavirus disease 2019 (COVID-19) but also
Externí odkaz:
https://doaj.org/article/3458f0ada0ce4f3c8f184dcf7ca0ff61
Autor:
Ronghui Liang, Zi-Wei Ye, Zhenzhi Qin, Yubin Xie, Xiaomeng Yang, Haoran Sun, Qiaohui Du, Peng Luo, Kaiming Tang, Bodan Hu, Jianli Cao, Xavier Hoi-Leong Wong, Guang-Sheng Ling, Hin Chu, Jiangang Shen, Feifei Yin, Dong-Yan Jin, Jasper Fuk-Woo Chan, Kwok-Yung Yuen, Shuofeng Yuan
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Host survival depends on the elimination of virus and mitigation of tissue damage. Herein, we report the modulation of D-mannose flux rewires the virus-triggered immunometabolic response cascade and reduces tissue damage. Safe and inexpensiv
Externí odkaz:
https://doaj.org/article/172ab913f5fd4fd68985cd7d66bf32cb
Autor:
Ronghui Liang, Zi-Wei Ye, Chon Phin Ong, Zhenzhi Qin, Yubin Xie, Yilan Fan, Kaiming Tang, Vincent Kwok-Man Poon, Chris Chung-Sing Chan, Xiaomeng Yang, Hehe Cao, Kun Wang, Haoran Sun, Bodan Hu, Jian-Piao Cai, Cuiting Luo, Kenn Ka-Heng Chik, Hin Chu, Yi Zheng, Kwok-Yung Yuen, Jasper Fuk-Woo Chan, Dong-Yan Jin, Shuofeng Yuan
Publikováno v:
Emerging Microbes and Infections, Vol 11, Iss 1, Pp 2093-2101 (2022)
The replication and pathogenicity of SARS-CoV-2 Omicron BA.2 are comparable to that of BA.1 in experimental animal models. However, BA.2 has rapidly emerged to overtake BA.1 to become the predominant circulating SARS-CoV-2 variant worldwide. Here, we
Externí odkaz:
https://doaj.org/article/b55a2f57759b43ee8b1fbc2b83098836
Autor:
Shuofeng Yuan, Bingpeng Yan, Jianli Cao, Zi-Wei Ye, Ronghui Liang, Kaiming Tang, Cuiting Luo, Jianpiao Cai, Hin Chu, Tom Wai-Hing Chung, Kelvin Kai-Wang To, Ivan Fan-Ngai Hung, Dong-Yan Jin, Jasper Fuk-Woo Chan, Kwok-Yung Yuen
Publikováno v:
Cell Discovery, Vol 7, Iss 1, Pp 1-13 (2021)
Abstract Coronavirus Disease 2019 (COVID-19) is predominantly a respiratory tract infection that significantly rewires the host metabolism. Here, we monitored a cohort of COVID-19 patients’ plasma lipidome over the disease course and identified tri
Externí odkaz:
https://doaj.org/article/d2814f42dcee49b08c5ae32c03158529
Autor:
Jianli Cao, Gang Lu, Lei Wen, Peng Luo, Yaoqiang Huang, Ronghui Liang, Kaiming Tang, Zhenzhi Qin, Chris Chun-Yiu Chan, Kenn Ka-Heng Chik, Jiang Du, Feifei Yin, Zi-Wei Ye, Hin Chu, Dong-Yan Jin, Kwok-Yung Yuen, Jasper Fuk-Woo Chan, Shuofeng Yuan
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 19, Iss , Pp 5568-5577 (2021)
Severe fever with thrombocytopenia syndrome virus (SFTSV) is an emerging tick-borne virus that causes severe infection in humans characterized by an acute febrile illness with thrombocytopenia and hemorrhagic complications, and a mortality rate of up
Externí odkaz:
https://doaj.org/article/600a7ac2b3d84dc7b758bb69ec80080a
Autor:
Andrew Chak-Yiu Lee, Anna Jinxia Zhang, Jasper Fuk-Woo Chan, Can Li, Zhimeng Fan, Feifei Liu, Yanxia Chen, Ronghui Liang, Siddharth Sridhar, Jian-Piao Cai, Vincent Kwok-Man Poon, Chris Chung-Sing Chan, Kelvin Kai-Wang To, Shuofeng Yuan, Jie Zhou, Hin Chu, Kwok-Yung Yuen
Publikováno v:
Cell Reports Medicine, Vol 1, Iss 7, Pp 100121- (2020)
Summary: Severe acute respiratory syndrome-coronavirus 2 (SARS-CoV-2) is transmitted largely by respiratory droplets or airborne aerosols. Despite being frequently found in the immediate environment and feces of patients, evidence supporting the oral
Externí odkaz:
https://doaj.org/article/21edabcf4e234fa3901efb621ce8ff70
Autor:
Yanping Li, Ronghui Liang, Xiaoya Zhang, Jiyan Wang, Changliang Shan, Shuangping Liu, Leilei Li, Shuai Zhang
Publikováno v:
Frontiers in Pharmacology, Vol 10 (2019)
Copper chaperone for superoxide dismutase (CCS) is a critical component of oxidation–reduction system and functions as a potential tumor promoter in several cancers. However, the function and clinical significance of CCS in breast cancer remain unc
Externí odkaz:
https://doaj.org/article/0d408022790a40388145a3924e26af99
Autor:
Zijiao Zou, Jessica Oi-Ling Tsang, Bingpeng Yan, Kenn Ka-Heng Chik, Chris Chun-Yiu Chan, Jianli Cao, Ronghui Liang, Kaiming Tang, Feifei Yin, Zi-Wei Ye, Hin Chu, Jasper Fuk-Woo Chan, Shuofeng Yuan, Kwok-Yung Yuen
Publikováno v:
Metabolites, Vol 10, Iss 8, p 302 (2020)
Enterovirus A71 (EV-A71) is a common cause of hand, foot, and mouth disease. Severe EV-A71 infections may be associated with life-threatening neurological complications. However, the pathogenic mechanisms underlying these severe clinical and patholog
Externí odkaz:
https://doaj.org/article/08b6968ebb154d72afd6745b84cf7afd
Autor:
Shuofeng Yuan, Chris Chun-Yiu Chan, Kenn Ka-Heng Chik, Jessica Oi-Ling Tsang, Ronghui Liang, Jianli Cao, Kaiming Tang, Jian-Piao Cai, Zi-Wei Ye, Feifei Yin, Kelvin Kai-Wang To, Hin Chu, Dong-Yan Jin, Ivan Fan-Ngai Hung, Kwok-Yung Yuen, Jasper Fuk-Woo Chan
Publikováno v:
Viruses, Vol 12, Iss 6, p 628 (2020)
The ongoing Coronavirus Disease 2019 (COVID-19) pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) signals an urgent need for an expansion in treatment options. In this study, we investigated the anti-SARS-CoV-2 activitie
Externí odkaz:
https://doaj.org/article/e3988b2d68314525a898ef675400293b
Autor:
Peng Luo, Kenn Ka-Heng Chik, Ronghui Liang, Zi-Wei Ye, Kwok-Yung Yuen, Kaiming Tang, Feifei Yin, Shuofeng Yuan, Lei Wen, Chris Chun-Yiu Chan, Gang Lu, Jasper Fuk-Woo Chan, Zhenzhi Qin, Hin Chu, Yaoqiang Huang, Jiang Du, Dong-Yan Jin, Jianli Cao
Publikováno v:
Computational and Structural Biotechnology Journal
Computational and Structural Biotechnology Journal, Vol 19, Iss, Pp 5568-5577 (2021)
Computational and Structural Biotechnology Journal, Vol 19, Iss, Pp 5568-5577 (2021)
Graphical abstract
Severe fever with thrombocytopenia syndrome virus (SFTSV) is an emerging tick-borne virus that causes severe infection in humans characterized by an acute febrile illness with thrombocytopenia and hemorrhagic complications, an
Severe fever with thrombocytopenia syndrome virus (SFTSV) is an emerging tick-borne virus that causes severe infection in humans characterized by an acute febrile illness with thrombocytopenia and hemorrhagic complications, an