Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Rongfeng Zou"'
Autor:
Wanbiao Chen, Rongfeng Zou, Yi Mei, Jiawei Li, Yumi Xuan, Bing Cui, Junjie Zou, Juncheng Wang, Shaoquan Lin, Zhe Zhang, Chongyuan Wang
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-10 (2024)
Abstract Pentamidine and melarsoprol are primary drugs used to treat the lethal human sleeping sickness caused by the parasite Trypanosoma brucei. Cross-resistance to these two drugs has recently been linked to aquaglyceroporin 2 of the trypanosome (
Externí odkaz:
https://doaj.org/article/08f848ff391c49bc9a605ec58e49cfdb
Autor:
Yao Xia, Rongfeng Zou, Maxime Escouboué, Liang Zhong, Chengjun Zhu, Cécile Pouzet, Xueqiang Wu, Yongjin Wang, Guohua Lv, Haibo Zhou, Pinghua Sun, Ke Ding, Laurent Deslandes, Shuguang Yuan, Zhi-Min Zhang
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-10 (2021)
The Yersinia outer protein J (YopJ) family of effectors, which are present in many plant and animal pathogens are non-canonical acetyltransferases that are activated by the eukaryote-specific cofactor inositol hexaphosphate (InsP6). Here, the authors
Externí odkaz:
https://doaj.org/article/aaf15f09eb474d80af8634f4bdfa1ed2
Autor:
Wenqiang Cui, Fei Yu, Yuefeng Zhang, Xiao Han, Rongfeng Zou, Yandong Tang, Linguang Wang, Nsabimana Eliphaz, Jian Wang, Shuguang Yuan, Xuehui Cai, Yanhua Li
Publikováno v:
Pharmacological Research - Modern Chinese Medicine, Vol 3, Iss , Pp 100104- (2022)
Externí odkaz:
https://doaj.org/article/da3b0e137cc14987989dd33c2404fb75
Autor:
Yingyi Zhang, Patricia M. Dijkman, Rongfeng Zou, Martina Zandl-Lang, Ricardo M. Sanchez, Luise Eckhardt-Strelau, Harald Köfeler, Horst Vogel, Shuguang Yuan, Mikhail Kudryashev
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Pentameric ligand-gated ion channels (pLGICs) are key players in neurotransmission and have been shown to be modulated by the lipid environment, however the underlying mechanism is not well understood. Here, the authors report structures of the pLGIC
Externí odkaz:
https://doaj.org/article/c3dc1144479e42dfbcbc8d743307e558
Autor:
Wenqiang Cui, Fei Yu, Yuefeng Zhang, Xiao Han, Rongfeng Zou, Yandong Tang, Linguang Wang, Nsabimana Eliphaz, Jian Wang, Shuguang Yuan, Xuehui Cai, Yanhua Li
Publikováno v:
Pharmacological Research - Modern Chinese Medicine, Vol 1, Iss , Pp 100003- (2021)
Porcine reproductive and respiratory syndrome (PRRS) is a highly contagious disease caused by the porcine reproductive and respiratory syndrome virus (PRRSV). It is characterized by reproductive disorders in pregnant sows and respiratory symptoms in
Externí odkaz:
https://doaj.org/article/3aa9dd9a3a164267912d16620ad67d02
Autor:
Qianwei Qu, Wenqiang Cui, Xiaoxu Xing, Rongfeng Zou, Xingyu Huang, Xiaozhen Wang, Tong Wu, God’spower Bello-Onaghise, Shuguang Yuan, Yanhua Li
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Staphylococcus xylosus (S. xylosus) has become an emerging opportunistic pathogen due to its strong biofilm formation ability. Simultaneously, the biofilm of bacteria plays an important role in antibiotic resistance and chronic infection. Here, we co
Externí odkaz:
https://doaj.org/article/aedbbaa911d6491090fa345b3bb25cea
Publikováno v:
Molecules, Vol 26, Iss 15, p 4625 (2021)
Protein–ligand interaction analysis is important for drug discovery and rational protein design. The existing online tools adopt only a single conformation of the complex structure for calculating and displaying the interactions, whereas both prote
Externí odkaz:
https://doaj.org/article/61bccf60148b46fdb84611f09764e26e
Publikováno v:
RSC Advances. 13:4422-4430
The sandwich structure in human melatonin receptors was disrupted. In MT1 this opened a gate for the water molecule from the bulk environment to fluctuate into the inner space. In MT2, the sandwich structure was stabilized by MEL during the whole MD
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eba04f75cc30bae00864d83b14188094
https://doi.org/10.1039/d2ra06693a
https://doi.org/10.1039/d2ra06693a
Publikováno v:
A Practical Guide to Recent Advances in Multiscale Modeling and Simulation of Biomolecules ISBN: 9780735425248
The kinetic properties in biological systems are important for understanding biomolecular functions and are of great importance for drug discovery. However, how to precisely calculate the kinetics of rare events occurring in biomolecular systems with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ca390565d6bd75bd639b624fd40ce739
https://doi.org/10.1063/9780735425279_008
https://doi.org/10.1063/9780735425279_008
Autor:
Shuguang Yuan, Pei-Hui Wang, Ximing Shao, H. C. Stephen Chan, Xueying Wang, Junlin Dong, Hongpei Li, Ke Liu, Wu Su, Meiqing Li, Hongchun Li, Hongchang Li, Rongfeng Zou, Cui Wenqiang
Publikováno v:
ACS Pharmacology & Translational Science
The outbreak of COVID-19 by the end of 2019 has posed serious health threats to humanity and jeopardized the global economy. However, no effective drugs are available to treat COVID-19 currently and there is a great demand to fight against it. Here,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f88e5195d7d699d8f221a1c699263ae
https://doi.org/10.1021/acsptsci.0c00163
https://doi.org/10.1021/acsptsci.0c00163