Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Rongfei Qin"'
Publikováno v:
ACS Omega, Vol 5, Iss 16, Pp 9614-9623 (2020)
Externí odkaz:
https://doaj.org/article/5c5078a290e84aba9a17ea36e88bd793
Autor:
Sarah M. Batt, Haihong Huang, Gang Li, Bin Wang, Lei Fu, Yu Lu, Peng-Xu Wang, Rongfei Qin, Gurdyal S. Besra
Publikováno v:
Journal of Medicinal Chemistry
In this study, we report the design and synthesis of a series of novel thiophene-arylamide compounds derived from the noncovalent decaprenylphosphoryl-β-d-ribose 2′-epimerase (DprE1) inhibitor TCA1 through a structure-based scaffold hopping strate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::536580c5e2b8d800da0123eeeaed483d
https://doi.org/10.1021/acs.jmedchem.1c00263
https://doi.org/10.1021/acs.jmedchem.1c00263
Publikováno v:
ACS Omega, Vol 5, Iss 16, Pp 9614-9623 (2020)
The one-pot synthesis of quinazoline-2,4-diones was developed in the presence of 4-dimethylaminopyridine (DMAP) by metal-free catalysis. The commercially available (Boc)2O acted as a key precursor in the construction of the 2-position carbonyl of qui
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d00feb0e31ed1e41a73ce0a6cdac5449
https://doi.org/10.1021/acsomega.0c01104
https://doi.org/10.1021/acsomega.0c01104
Autor:
Rongfei Qin, Pengxu Wang, Bin Wang, Lei Fu, Sarah M. Batt, Gurdyal S. Besra, Chengwei Wu, Yanan Wang, Haihong Huang, Yu Lu, Gang Li
Publikováno v:
European journal of medicinal chemistry. 231
A series of thiophene-benzenesulfonamide derivatives was designed and synthesized by exploring the structure-activity relationship of lead compounds 2,3-disubstituted thiophenes 25a and 297F as antituberculosis agents, which displayed potent antimyco
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b85873914ca4d495f9ce06dd1ac2311
https://pubmed.ncbi.nlm.nih.gov/35101648
https://pubmed.ncbi.nlm.nih.gov/35101648