Zobrazeno 1 - 10
of 131
pro vyhledávání: '"Rongfang, Liu"'
Publikováno v:
BMC Pulmonary Medicine, Vol 24, Iss 1, Pp 1-9 (2024)
Abstract Objective The aim of this research was to examine how penehyclidine hydrochloride (PHC) impacts the occurrence of pyroptosis in lung tissue cells within a rat model of lung ischemia-reperfusion injury. Methods Twenty-four Sprague Dawley (SD)
Externí odkaz:
https://doaj.org/article/b42a280836a64de3ae0d4101fed9c94c
Autor:
Marina Gorostiola González, Hubert J. Sijben, Laura Dall’ Acqua, Rongfang Liu, Adriaan P. IJzerman, Laura H. Heitman, Gerard J. P. van Westen
Publikováno v:
Frontiers in Molecular Biosciences, Vol 10 (2023)
Glutamate is an essential excitatory neurotransmitter and an intermediate for energy metabolism. Depending on the tumor site, cancer cells have increased or decreased expression of excitatory amino acid transporter 1 or 2 (EAAT1/2, SLC1A3/2) to regul
Externí odkaz:
https://doaj.org/article/db6bd9e55f7a43348580c6357b600742
Autor:
Xue-Quan Zhou, Imma Carbo-Bague, Maxime A. Siegler, Jonathan Hilgendorf, Uttara Basu, Ingo Ott, Rongfang Liu, Liyan Zhang, Vadde Ramu, Adriaan P. IJzerman, Sylvestre Bonnet
Publikováno v:
JACS Au, Vol 1, Iss 4, Pp 380-395 (2021)
Externí odkaz:
https://doaj.org/article/a2ea25150f2e4a8b9304c5304229f266
Autor:
Hubert J. Sijben, Laura Dall’ Acqua, Rongfang Liu, Abigail Jarret, Eirini Christodoulaki, Svenja Onstein, Gernot Wolf, Simone J. Verburgt, Sylvia E. Le Dévédec, Tabea Wiedmer, Giulio Superti-Furga, Adriaan P. IJzerman, Laura H. Heitman
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Excitatory amino acid transporters (EAAT/SLC1) mediate Na+-dependent uptake of extracellular glutamate and are potential drug targets for neurological disorders. Conventional methods to assess glutamate transport in vitro are based on radiolabels, fl
Externí odkaz:
https://doaj.org/article/3013a65420c249ca84a2b5a7b907dc82
Autor:
David Ruano-Ordás, Lindsey Burggraaff, Rongfang Liu, Cas van der Horst, Laura H. Heitman, Michael T. M. Emmerich, Jose R. Mendez, Iryna Yevseyeva, Gerard J. P. van Westen
Publikováno v:
Journal of Cheminformatics, Vol 11, Iss 1, Pp 1-14 (2019)
Abstract Drugs have become an essential part of our lives due to their ability to improve people’s health and quality of life. However, for many diseases, approved drugs are not yet available or existing drugs have undesirable side effects, making
Externí odkaz:
https://doaj.org/article/5a8cd3db63674798b6d602071f656386
Publikováno v:
Biotechnology & Biotechnological Equipment, Vol 33, Iss 1, Pp 1380-1391 (2019)
This study investigated the phenotype and function of natural killer T (NKT) cells infiltrating cervical cancer tissues, in an attempt to understand the regulation of NKT cells by cervical cancer cells. Forty-two patients with cervical cancer were in
Externí odkaz:
https://doaj.org/article/02ef25a550d44c0fabbb0db975cb4cd0
Autor:
Chenlin Feng, Xuesong Wang, Willem Jespers, Rongfang Liu, Sofía Denise Zamarbide Losada, Marina Gorostiola González, Gerard J. P. van Westen, Erik H. J. Danen, Laura H. Heitman
Publikováno v:
Molecules, Vol 27, Iss 15, p 4676 (2022)
The adenosine A2A receptor (A2AAR) is a class A G-protein-coupled receptor (GPCR). It is an immune checkpoint in the tumor micro-environment and has become an emerging target for cancer treatment. In this study, we aimed to explore the effects of can
Externí odkaz:
https://doaj.org/article/5803a9d99c9d466d9eadda40f93ce3bd
Autor:
Jan Phillip Lemmerhirt, Andreas Isaak, Rongfang Liu, Max Kock, Constantin G. Daniliuc, Kenneth A. Jacobson, Laura H. Heitman, Anna Junker
Publikováno v:
Molecules, Vol 27, Iss 7, p 2283 (2022)
The adenosine A3 receptor is a promising target for treating and diagnosing inflammation and cancer. In this paper, a series of bicyclo[3.1.0]hexane-based nucleosides was synthesized and evaluated for their P1 receptor affinities in radioligand bindi
Externí odkaz:
https://doaj.org/article/ff4540a03cd6405b9529e70cd9c00188
Publikováno v:
Green Chemistry. 25:1672-1678
The first metal-free acceptorless dehydrogenative cross-coupling of aldehydes/alcohols with alcohols to furnish esters has been developed by synergistic catalysis of the organophotocatalyst 4CzIPN and a thiol under blue light irradiation.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::782619bf816d43bb75b28c8367848e5e
https://doi.org/10.1039/d2gc04594j
https://doi.org/10.1039/d2gc04594j
Autor:
González, Marina Gorostiola, Sijben, Hubert J., Acqua, Laura Dall', Rongfang Liu, IJzerman, Adriaan P., Heitman, Laura H., van Westen, Gerard J. P.
Publikováno v:
Frontiers in Molecular Biosciences; 2023, p1-18, 18p