Effects of allopurinol and febuxostat on uric acid transport and transporter expression in human umbilical vein endothelial cells.

Autor: van der Pol KH; Department of Internal Medicine, Radboud University Medical Center, Nijmegen, The Netherlands.; Department of Pharmacology and Toxicology, Radboud University Medical Center, Nijmegen, The Netherlands., Koenderink J; Department of Pharmacology and Toxicology, Radboud University Medical Center, Nijmegen, The Netherlands., van den Heuvel JJMW; Department of Pharmacology and Toxicology, Radboud University Medical Center, Nijmegen, The Netherlands., van den Broek P; Department of Pharmacology and Toxicology, Radboud University Medical Center, Nijmegen, The Netherlands., Peters J; Department of Pharmacology and Toxicology, Radboud University Medical Center, Nijmegen, The Netherlands., van Bunningen IDW; Department of Pharmacology and Toxicology, Radboud University Medical Center, Nijmegen, The Netherlands., Pertijs J; Department of Pharmacology and Toxicology, Radboud University Medical Center, Nijmegen, The Netherlands., Russel FGM; Department of Pharmacology and Toxicology, Radboud University Medical Center, Nijmegen, The Netherlands., Koldenhof J; Applied Stem Cell Technologies, University of Twente, Enschede, The Netherlands., Morshuis WJ; Department of Cardio-thoracic Surgery, Radboud University Medical Center, Nijmegen, The Netherlands., van Drongelen J; Department of Obstetrics and Gynaecology, Radboud University Medical Center, Nijmegen, The Netherlands., Schirris TJJ; Department of Pharmacology and Toxicology, Radboud University Medical Center, Nijmegen, The Netherlands., van der Meer A; Applied Stem Cell Technologies, University of Twente, Enschede, The Netherlands., Rongen GA; Department of Internal Medicine, Radboud University Medical Center, Nijmegen, The Netherlands.; Department of Pharmacology and Toxicology, Radboud University Medical Center, Nijmegen, The Netherlands.

Publikováno v: PloS one [PLoS One] 2024 Jun 21; Vol. 19 (6), pp. e0305906. Date of Electronic Publication: 2024 Jun 21 (Print Publication: 2024).

Dutch pharmacogenetics working group (DPWG) guideline for the gene-drug interaction of CYP2D6 and COMT with atomoxetine and methylphenidate.

Autor: Nijenhuis M; Royal Dutch Pharmacists Association (KNMP), The Hague, The Netherlands. M.Nijenhuis@knmp.nl., Soree B; Royal Dutch Pharmacists Association (KNMP), The Hague, The Netherlands., Jama WOM; Royal Dutch Pharmacists Association (KNMP), The Hague, The Netherlands., de Boer-Veger NJ; Pharmacy Boterdiep, Groningen, The Netherlands., Buunk AM; Pharmacy De Katwijkse Apotheek, Katwijk, The Netherlands., Guchelaar HJ; Department of Clinical Pharmacy & Toxicology, Leiden University Medical Center, Leiden, The Netherlands., Houwink EJF; Department of Public Health and Primary Care (PHEG), Leiden University Medical Center, Leiden, The Netherlands.; Department of Family Medicine, Mayo Clinic, Rochester, MIN, USA., Rongen GA; Department of Pharmacology and Toxicology, Radboud University Medical Centre, Nijmegen, The Netherlands.; Department of Internal Medicine, Radboud University Medical Center, Nijmegen, The Netherlands., van Schaik RHN; Department of Clinical Chemistry, Erasmus University Medical Center, Rotterdam, The Netherlands., Swen JJ; Department of Clinical Pharmacy & Toxicology, Leiden University Medical Center, Leiden, The Netherlands., Touw D; Department of Pharmaceutical Analysis, Groningen Research Institute of Pharmacy, University of Groningen, Groningen, The Netherlands., van der Weide J; Department of Clinical Chemistry, St. Jansdal Hospital, Harderwijk, The Netherlands., van Westrhenen R; Parnassia Psychiatric Institute/PsyQ, Amsterdam, The Netherlands.; Department of Psychiatry & Neuropsychology, Faculty of Health, Medicine and Life Sciences, Maastricht University, Maastricht, The Netherlands.; Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, UK., Deneer VHM; Department of Clinical Pharmacy, Division Laboratories, Pharmacy and Biomedical Genetics, University Medical Centre Utrecht, Utrecht, The Netherlands.; Division of Pharmacoepidemiology and Clinical Pharmacology, Utrecht Institute for Pharmaceutical Sciences (UIPS), Department of Pharmaceutical Sciences, Utrecht University, Utrecht, The Netherlands., Risselada A; Department of Clinical Pharmacy, Wilhelmina Hospital, Assen, The Netherlands.

Publikováno v: European journal of human genetics : EJHG [Eur J Hum Genet] 2023 Dec; Vol. 31 (12), pp. 1364-1370. Date of Electronic Publication: 2022 Dec 12.

Clinical differences in sirolimus treatment with low target levels between children and adults with vascular malformations - A nationwide trial.

Autor: Harbers VEM; Department of Medical Imaging, Radboud University Medical Center, Nijmegen, The Netherlands.; Radboudumc Center of Expertise HECOVAN, Amalia Children's Hospital, Radboud University Medical Center, Nijmegen, The Netherlands., Zwerink LGJM; Radboudumc Center of Expertise HECOVAN, Amalia Children's Hospital, Radboud University Medical Center, Nijmegen, The Netherlands.; Department of Dermatology, Radboud University Medical Center, Nijmegen, The Netherlands., Rongen GA; Department of Internal Medicine and Pharmacology-Toxicology, Radboud University Medical Center, Nijmegen, The Netherlands., Klein WM; Department of Medical Imaging, Radboud University Medical Center, Nijmegen, The Netherlands.; Radboudumc Center of Expertise HECOVAN, Amalia Children's Hospital, Radboud University Medical Center, Nijmegen, The Netherlands., van der Vleuten CJM; Radboudumc Center of Expertise HECOVAN, Amalia Children's Hospital, Radboud University Medical Center, Nijmegen, The Netherlands.; Department of Dermatology, Radboud University Medical Center, Nijmegen, The Netherlands.; VASCERN ERN on Rare Multisystemic Vascular Diseases, Healthcare Provider Coordinator: Assistance Publique-Hôpitaux de Paris, Hôpital Bichat-Claude Bernard, Centre de Réference (CRMR) Syndromes de Marfan et apparentés, Paris, France., van Rijnsoever IMP; Radboudumc Center of Expertise HECOVAN, Amalia Children's Hospital, Radboud University Medical Center, Nijmegen, The Netherlands.; Department of Pediatrics, Amalia Children's Hospital, Radboud University Medical Center, Nijmegen, The Netherlands., Gerdsen-Drury L; Department of Medical Imaging, Radboud University Medical Center, Nijmegen, The Netherlands., Flucke UE; Radboudumc Center of Expertise HECOVAN, Amalia Children's Hospital, Radboud University Medical Center, Nijmegen, The Netherlands.; Department of Pathology, Radboud University Medical Center, Nijmegen, The Netherlands., Verhoeven BH; Radboudumc Center of Expertise HECOVAN, Amalia Children's Hospital, Radboud University Medical Center, Nijmegen, The Netherlands.; Department of Surgery, Radboud University Medical Center, Nijmegen, The Netherlands., de Laat PCJ; Department of Pediatric Oncology, WEVAR-Team Rotterdam Erasmus MC-Sophia, Rotterdam, The Netherlands., van der Horst CMAM; Department of Plastic Reconstructive and Hand Surgery, AVA-Team, Amsterdam University Medical Center, Amsterdam, The Netherlands., Schultze Kool LJ; Department of Medical Imaging, Radboud University Medical Center, Nijmegen, The Netherlands.; Radboudumc Center of Expertise HECOVAN, Amalia Children's Hospital, Radboud University Medical Center, Nijmegen, The Netherlands.; VASCERN ERN on Rare Multisystemic Vascular Diseases, Healthcare Provider Coordinator: Assistance Publique-Hôpitaux de Paris, Hôpital Bichat-Claude Bernard, Centre de Réference (CRMR) Syndromes de Marfan et apparentés, Paris, France., Te Loo DMWM; Radboudumc Center of Expertise HECOVAN, Amalia Children's Hospital, Radboud University Medical Center, Nijmegen, The Netherlands.; Department of Pediatric Hematology, Amalia Children's Hospital, Radboud University Medical Center, Nijmegen, The Netherlands.

Publikováno v: Clinical and translational science [Clin Transl Sci] 2023 May; Vol. 16 (5), pp. 781-796. Date of Electronic Publication: 2023 Feb 23.

The scientific basis of rational prescribing. A guide to precision clinical pharmacology based on the WHO 6-step method.

Autor: Rongen GA; Department of Pharmacology and Toxicology and Department of Internal Medicine Radboudumc, PO Box 9101, 6500 HB, Nijmegen, The Netherlands. Gerard.Rongen@Radboudumc.nl., Marquet P; Centre de Biologie et de Recherche en Santé, Faculté de Médecine, Université de Limoges, 2 rue du Prof. Descottes, 87000, Limoges CEDEX, France., van Gerven JMA; Centrale Commissie Mensgebonden Onderzoek, PO Box 16302, 2500 BH, The Hague, The Netherlands.

Publikováno v: European journal of clinical pharmacology [Eur J Clin Pharmacol] 2021 May; Vol. 77 (5), pp. 677-683. Date of Electronic Publication: 2020 Nov 18.

Crystal-proven gout patients have an increased mortality due to cardiovascular diseases, cancer, and infectious diseases especially when having tophi and/or high serum uric acid levels: a prospective cohort study.

Autor: Disveld IJM; Department of Rheumatology, Rijnstate Hospital, Arnhem, The Netherlands., Zoakman S; Department of Rheumatology, Rijnstate Hospital, Arnhem, The Netherlands., Jansen TLTA; Department of Rheumatology, VieCuri Medical Centre, Venlo, Tegelseweg 210, 5912, BL, Venlo, The Netherlands., Rongen GA; Departments of Internal Medicine and Pharmacology and Toxicology, Radboud University Medical Centre, Nijmegen, The Netherlands., Kienhorst LBE; Department of Dermatology, University Medical Centre Utrecht, Utrecht, The Netherlands., Janssens HJEM; Department of Primary and Community Care, Radboud University Medical Centre, Nijmegen, The Netherlands., Fransen J; Department of Rheumatology, Radboud University Medical Centre, Nijmegen, The Netherlands., Janssen M; Department of Rheumatology, VieCuri Medical Centre, Venlo, Tegelseweg 210, 5912, BL, Venlo, The Netherlands. matthijsjanssen@icloud.com.

Publikováno v: Clinical rheumatology [Clin Rheumatol] 2019 May; Vol. 38 (5), pp. 1385-1391. Date of Electronic Publication: 2019 Mar 30.