Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Rongbo Wen"'
Autor:
Hao Fan, Xuefei Hu, Fuao Cao, Leqi Zhou, Rongbo Wen, Hao Shen, Yating Fu, Xiaoming Zhu, Hang Jia, Zixuan Liu, Guimin Wang, Guanyu Yu, Wenjun Chang, Wei Zhang
Publikováno v:
npj Precision Oncology, Vol 8, Iss 1, Pp 1-13 (2024)
Abstract Protein tyrosine phosphatase SHP2 activates RAS signaling, which is a novel target for colorectal cancer (CRC) therapy. However, SHP2 inhibitor monotherapy is ineffective for metastatic CRC and a combination therapy is required. In this stud
Externí odkaz:
https://doaj.org/article/5452f55c0d5640f2a58081fe82de3dbe
Autor:
Tianshuai Zhang, Rongbo Wen, Hao Fan, Yue Yu, Hang Jia, Zhiying Peng, Leqi Zhou, Guanyu Yu, Wei Zhang
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Solid gastrointestinal tumors often respond poorly to immunotherapy for the complex tumor microenvironment (TME), which is exacerbated by immune system alterations. Immunosenescence is the process of increased diversification of immune genes due to a
Externí odkaz:
https://doaj.org/article/281c95cd2f5641f69f131249e3ed56c4
Autor:
Wei Zhang, Xianhua Gao, Yue Yu, Leqi Zhou, Guanyu Yu, Rongbo Wen, Hang Jia, Tianshuai Zhang, Zhiying Peng, Hao Fan, Anfu Pan, Xiaoming Zhu, Haifeng Gong, Zheng Lou
Publikováno v:
BMJ Open, Vol 13, Iss 9 (2023)
Introduction Neoadjuvant chemoradiotherapy (nCRT) could bring tumour shrinking and downstaging and increase the probability of organ preservation for patients with low rectal cancer. But for ultra-low rectal cancer, there is little possibility for or
Externí odkaz:
https://doaj.org/article/61aec72547e5427aa0e6235055cc3685
Autor:
Rongbo Wen, Leqi Zhou, Zhiying Peng, Hao Fan, Tianshuai Zhang, Hang Jia, Xianhua Gao, Liqiang Hao, Zheng Lou, Fuao Cao, Guanyu Yu, Wei Zhang
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Colorectal Cancer (CRC) is one of the most common gastrointestinal tumors, and its high tumor heterogeneity makes traditional sequencing methods incapable of obtaining information about the heterogeneity of individual cancer cells in CRC. Therefore,
Externí odkaz:
https://doaj.org/article/93eecc2f9458445b98bf392df90b9f43
Autor:
Nanxin Zheng, Rongbo Wen, Leqi Zhou, Qingying Meng, Kuo Zheng, Zhixuan Li, Fuao Cao, Wei Zhang
Publikováno v:
Translational Oncology, Vol 27, Iss , Pp 101570- (2023)
Background: : The tumor microenvironment (TME) plays a critical role in shaping tumor progression and determining the outcome of the therapeutic response. In this study, we aimed to generate a comprehensive cellular landscape of the colorectal cancer
Externí odkaz:
https://doaj.org/article/4aafdbabcc6945d9ad2d577da041f4c0
Autor:
Leqi Zhou, Yue Yu, Rongbo Wen, Kuo Zheng, Siyuan Jiang, Xiaoming Zhu, Jinke Sui, Haifeng Gong, Zheng Lou, Liqiang Hao, Guanyu Yu, Wei Zhang
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
BackgroundMost prognostic signatures for colorectal cancer (CRC) are developed to predict overall survival (OS). Gene signatures predicting recurrence-free survival (RFS) are rarely reported, and postoperative recurrence results in a poor outcome. Th
Externí odkaz:
https://doaj.org/article/858dddf687bf479191c9c7a54c835598
Autor:
Kuo Zheng, Nanxin Zheng, Cheng Xin, Leqi Zhou, Ge Sun, Rongbo Wen, Hang Zhang, Guanyu Yu, Chenguang Bai, Wei Zhang
Publikováno v:
Gastroenterology Research and Practice, Vol 2020 (2020)
Background. The prognostic value of tumor deposit (TD) count in colorectal cancer (CRC) patients has been rarely evaluated. This study is aimed at exploring the prognostic value of TD count and finding out the optimal cutoff point of TD count to diff
Externí odkaz:
https://doaj.org/article/f851a1a360b245a5b5149d949c624a4d
Autor:
Kuo Zheng, Nanxin Zheng, Cheng Xin, Leqi Zhou, Ge Sun, Rongbo Wen, Hang Zhang, Guanyu Yu, Chenguang Bai, Wei Zhang
Publikováno v:
Gastroenterology Research and Practice, Vol 2020 (2020)
Externí odkaz:
https://doaj.org/article/306b8adffc8b4da88861f6cbf52d2b0a
Autor:
Xu Guan, Guanyu Yu, Weiyuan Zhang, Rongbo Wen, Ran Wei, Shuai Jiao, Qing Zhao, Zheng Lou, Liqiang Hao, Enrui Liu, Xianhua Gao, Guiyu Wang, Wei Zhang, Xishan Wang
Publikováno v:
International Journal of Surgery. 109:255-265
Autor:
Ge Sun, Zheng Lou, Kuo Zheng, Yuntao Chen, Hang Zhang, Rongbo Wen, Xianhua Gao, Ronggui Meng, Haifeng Gong, Chenguang Bai, Edgar J.B. Furnée, Wei Zhang
Publikováno v:
Langenbeck's Archives of Surgery, 408:208. SPRINGER
Purpose: Conformal sphincter preservation operation (CSPO) procedure is a sphincter preservation procedure for preserving the anal canal function for very low rectal cancers. This study investigated the functional and oncological outcome of conformal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::feb2223f68b109ad65792ee55230e08c
https://research.rug.nl/en/publications/9d089d9e-c2cd-40cd-b91e-500b95bb2aab
https://research.rug.nl/en/publications/9d089d9e-c2cd-40cd-b91e-500b95bb2aab