Zobrazeno 1 - 10
of 130
pro vyhledávání: '"Rong-guang Shao"'
Autor:
Wen-ping Song, Si Zheng, Hong-juan Yao, Xiao-fei Zhou, Rui Li, Cheng-yue Zhang, Jun-yang Zhao, Lie-wei Wang, Rong-guang Shao, Liang Li
Publikováno v:
BMC Ophthalmology, Vol 20, Iss 1, Pp 1-11 (2020)
Abstract Background Retinoblastoma (RB) is the most frequent pediatric retinal tumor. In the present study, to elucidate chemoresistance mechanisms and identify potential biomarkers in RB, we utilized RNA sequencing (RNAseq) technological platforms t
Externí odkaz:
https://doaj.org/article/f1c3f88607cc4a88864943dca6c7a9b8
Autor:
Rong-Guang Shao, Shi-Ying Cai, Chang-Liang Xu, Ju-Xian Wang, Xiao-Guang Bai, Hong-Wei He, Hong-Tao Liu, Yu-Cheng Wang
Publikováno v:
Molecules, Vol 18, Iss 6, Pp 6883-6897 (2013)
The apical sodium-dependent bile salt transporter (ASBT) plays a pivotal role in maintaining bile acid homeostasis. Inhibition of ASBT would reduce bile acid pool size and lower cholesterol levels. In this report, a series of novel arylsulfonylaminob
Externí odkaz:
https://doaj.org/article/74be97d8ff37447ca2417e02c84560b7
Autor:
Sheng-hua Zhang, Hao Zhang, Hong-wei He, Yi Li, Xiao-ying Li, Lian-feng Zhang, Rong-guang Shao
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 1, Iss 4, Pp 220-225 (2011)
Human xenograft mouse models, which have been used in cancer research for over a century, provided significant advances for our understanding of this multifaceted family of diseases. Orthotopic transplantation tumor models are emerging as the prefere
Externí odkaz:
https://doaj.org/article/d985fc51554f496d946a654e0dc3f204
Autor:
Junxia Wang, Cong-Hui Zhang, Rong-Guang Shao, Mengyan Wang, Yuhan Qiu, Huimin Zhou, Mei-Lian Cai, Xiujun Liu, Minghua Chen, Wuli Zhao, Wenxia Zhao, Tianshu Zhang, Shuyi Si
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 12, Iss 1, Pp 210-227 (2022)
Pancreatic adenocarcinoma (PAAD) is one of the most lethal malignancies. Although gemcitabine (GEM) is a standard treatment for PAAD, resistance limits its application and therapy. Secoemestrin C (Sec C) is a natural compound from the endophytic fung
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2229821d50da179f24c33380fbeb64c
https://doi.org/10.1016/j.apsb.2021.07.004
https://doi.org/10.1016/j.apsb.2021.07.004
Autor:
Wuli Zhao, Xiao-Fang Chen, Cong-Hui Zhang, Tianshu Zhang, Yuhan Qiu, Huimin Zhou, Mei-Lian Cai, Xiao-Wei Wang, Wenxia Zhao, Rong-Guang Shao, Mengyan Wang
Publikováno v:
Journal of Drug Targeting. 29:576-591
Mitophagy is a selective form of macroautophagy in which dysfunctional and damaged mitochondria can be efficiently degraded, removed and recycled through autophagy. Selective removal of damaged or fragmented mitochondria is critical to the functional
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2169b65124ebf0955b7c1932831b320a
https://doi.org/10.1080/1061186x.2020.1867992
https://doi.org/10.1080/1061186x.2020.1867992
Autor:
Guimin Xia, Rong-Guang Shao, Mengyan Wang, Cong-Hui Zhang, Xiao-Wei Wang, Tianshu Zhang, Wenxia Zhao, Yuhan Qiu, Wuli Zhao, Huimin Zhou
Publikováno v:
International Journal of Nanomedicine. 15:9447-9467
Nanomedicines (NMs) have played an increasing role in cancer therapy as carriers to efficiently deliver therapeutics into tumor cells. For this application, the uptake of NMs by tumor cells is usually a prerequisite to deliver the cargo to intracellu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::088ddf7041094fb49978851825fcde89
https://doi.org/10.2147/ijn.s274289
https://doi.org/10.2147/ijn.s274289
Autor:
Lan Sun, Jingcao Li, Yao Hongjuan, Liang Li, Xiaofei Zhou, Rong-Guang Shao, Li Rui, Yingge Zhang
Publikováno v:
International Journal of Nanomedicine. 15:7013-7034
Purpose Gastric cancer stem cells (CSCs) are important for the initiation, growth, recurrence, and metastasis of gastric cancer, due to their chemo-resistance and indefinite proliferation. Herein, to eliminate gastric CSCs, we developed novel CSC-tar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::22bfa443c86af14713e91f02f6449ffc
https://doi.org/10.2147/ijn.s260163
https://doi.org/10.2147/ijn.s260163
Autor:
Dan-Qing Song, Rong-Guang Shao, Mengyan Wang, Wuli Zhao, Cheng Ye, Yan Xing, Chong-Wen Bi, Yuhan Qiu, Yi Li, Xiujun Liu
Publikováno v:
Acta Pharmacologica Sinica
Sophoridine is a quinolizidine natural product and the exploration of its derivatives has been carried out, and the potent anticancer compound IMB-HDC was acquired. Although previous studies have revealed that some sophoridine derivatives could induc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a195c2e09cd49d3eb2df404c0d73e857
https://doi.org/10.1038/s41401-019-0333-6
https://doi.org/10.1038/s41401-019-0333-6
Autor:
Yucheng Wang, Juxian Wang, Rong-Guang Shao, Na Zhang, Hongwei He, Shuang-shuang Zhao, Yi-xuan Zhang
Publikováno v:
Acta Pharmacologica Sinica
Chronic tissue injury with fibrosis results in the disruption of tissue architecture, organ dysfunction, and eventual organ failure. Therefore, the development of effective antifibrotic drugs is urgently required. IMB-S7 is novel biphenyl compound de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bebce6b265fb2c0f04122d73edbc9026
http://europepmc.org/articles/PMC7470799
http://europepmc.org/articles/PMC7470799
Autor:
Junxia Wang, Hongwei He, Hong Liu, Wuli Zhao, Gui-Ming Xia, Cong-Hui Zhang, Mei-Lian Cai, Rong-Guang Shao, Mengyan Wang
Publikováno v:
Journal of Drug Targeting. 28:23-32
Src family kinases (SFKs) are non-receptor tyrosine kinases and are involved in various cellular functions (proliferation, differentiation, migration, survival and invasion) by regulating downstream pathways. Considerable evidence suggests that co- a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53de17404c08dd7c2e415c60d45b5033
https://doi.org/10.1080/1061186x.2019.1616297
https://doi.org/10.1080/1061186x.2019.1616297