Zobrazeno 1 - 10
of 158
pro vyhledávání: '"Rong-fu Wang"'
Autor:
Lang Chen, Hongwei Yi, Qingtian Li, Tianhao Duan, Xin Liu, Linfeng Li, Helen Y. Wang, Changsheng Xing, Rong‐Fu Wang
Publikováno v:
Advanced Science, Vol 11, Iss 28, Pp n/a-n/a (2024)
Abstract T‐bet, encoded by TBX21, is extensively expressed across various immune cell types, and orchestrates critical functions in their development, survival, and physiological activities. However, the role of T‐bet in non‐immune compartments
Externí odkaz:
https://doaj.org/article/2f77424b65084d95aa8bcb444d0e19c5
Publikováno v:
PLoS Genetics, Vol 19, Iss 3, p e1010701 (2023)
[This corrects the article DOI: 10.1371/journal.pgen.1004524.].
Externí odkaz:
https://doaj.org/article/033011c0092f48e4add95d5a3b18fc1f
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
The efficacious detection of pathogens and prompt induction of innate immune signaling serve as a crucial component of immune defense against infectious pathogens. Over the past decade, DNA-sensing receptor cyclic GMP-AMP synthase (cGAS) and its down
Externí odkaz:
https://doaj.org/article/8c81a6110be7475e81285f1d88e24e7b
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Colorectal cancer (CRC) is one of the leading causes of cancer-related death in the world. Besides genetic causes, colonic inflammation is one of the major risk factors for CRC development, which is synergistically regulated by multiple components, i
Externí odkaz:
https://doaj.org/article/532fe09f5e7349ef93bb9594fce506ee
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Innate immunity is the first defense system against invading pathogens. Toll-like receptors (TLRs) are well-defined pattern recognition receptors responsible for pathogen recognition and induction of innate immune responses. Since their discovery, TL
Externí odkaz:
https://doaj.org/article/9e0162d7522a4fa4a697b7f2a4faa325
Publikováno v:
Journal of Neuroinflammation, Vol 16, Iss 1, Pp 1-14 (2019)
Abstract Development of central nervous system (CNS) is regulated by both intrinsic and peripheral signals. Previous studies have suggested that environmental factors affect neurological activities under both physiological and pathological conditions
Externí odkaz:
https://doaj.org/article/4e52c510f4ca49cb89c9ae6b44ac2f86
Autor:
Qianquan Ma, Wenyong Long, Changsheng Xing, Chongming Jiang, Jun Su, Helen Y. Wang, Qing Liu, Rong-Fu Wang
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
Glioblastoma (GBM) stem cells are resistant to cancer therapy, and therefore responsible for tumor progression and recurrence after conventional therapy. However, the molecular mechanisms driving the maintenance of stemness and dedifferentiation are
Externí odkaz:
https://doaj.org/article/bbfdd06260534e8886036b2ffe613576
Autor:
Yufu Zhou, Ning Shao, Ricardo Bessa de Castro, Pengchao Zhang, Yuan Ma, Xin Liu, Feizhou Huang, Rong-Fu Wang, Lidong Qin
Publikováno v:
Cell Reports, Vol 31, Iss 4, Pp - (2020)
Summary: Comprehensive evaluation of single T cell functions such as cytokine secretion and cytolysis of target cells is greatly needed in adoptive cell therapy (ACT) but has never been fully fulfilled by current approaches. Herein, we develop a hier
Externí odkaz:
https://doaj.org/article/5824e0b9412e45449d51dc9529a63e5f
Autor:
Xiao Yu, Yang Du, Chunmei Cai, Baowei Cai, Motao Zhu, Changsheng Xing, Peng Tan, Meng Lin, Jian Wu, Jian Li, Mingjun Wang, Helen Y. Wang, Xin-zhuan Su, Rong-Fu Wang
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
The inflammasome is an essential component of inflammatory processes and the host response to infection. Here the authors show that inflammasome activation modulates MyD88-IRF7 type I IFN signalling and anti-malaria immunity.
Externí odkaz:
https://doaj.org/article/139d3e3e79e44205a9c09f58cb4163c5
Autor:
Sen Zhu, Dongyu Zhao, Lin Yan, Weihua Jiang, Jung-Sun Kim, Bingnan Gu, Qipeng Liu, Rui Wang, Bo Xia, Jonathan C. Zhao, Gang Song, Wenyi Mi, Rong-Fu Wang, Xiaobing Shi, Hung-Ming Lam, Xuesen Dong, Jindan Yu, Kaifu Chen, Qi Cao
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
The polycomb group protein BMI1 is highly expressed in prostate cancer. Here, the authors demonstrate that BMI1 directly interacts with AR leading to increased AR signaling independently of PRC1 complex and that targeting BMI1 inhibits tumor growth o
Externí odkaz:
https://doaj.org/article/2c11102c772b403f8c968a42953aed26