Faraday Waves-Based Integrated Ultrasonic Micro-Droplet Generator and Applications

Autor: Chen S. Tsai, Rong W. Mao, Shirley C. Tsai, Kaveh Shahverdi, Yun Zhu, Shih K. Lin, Yu-Hsiang Hsu, Gerry Boss, Matt Brenner, Sari Mahon, Gerald C. Smaldone

Publikováno v: Micromachines, Vol 8, Iss 2, p 56 (2017)

An in-depth review on a new ultrasonic micro-droplet generator which utilizes megahertz (MHz) Faraday waves excited by silicon-based multiple Fourier horn ultrasonic nozzles (MFHUNs) and its potential applications is presented. The new droplet genera

Externí odkaz: https://doaj.org/article/1f1ec22bcb454a57a08d542b0205fded

Faraday instability-based micro droplet ejection for inhalation drug delivery

Autor: Shirley C. Tsai, Shih K. Lin, Chen S. Tsai, Rong W. Mao, Yun Zhu

Publikováno v: TECHNOLOGY. :75-81

We report here the technology and the underlying science of a new device for inhalation (pulmonary) drug delivery which is capable of fulfilling needs unmet by current commercial devices. The core of the new device is a centimeter-size clog-free sili

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::745975864e1a3297103c0d36e8cbea42
https://doi.org/10.1142/s233954781450006x

MEMS-based silicon ultrasonic twin-nozzle nebulizer for inhalation drug delivery

Autor: Chen S. Tsai, Gerald C. Smaldone, Matthew Brenner, Gerry R. Boss, Sari B. Mahon, Rong W. Mao, Shirley C. Tsai, Shih K. Lin

Publikováno v: Mao, RW; Lin, SK; Tsai, SC; Brenner, M; Mahon, S; Boss, G; et al.(2014). MEMS-based silicon ultrasonic twin-nozzle nebulizer for inhalation drug delivery. IEEE International Ultrasonics Symposium, IUS, 742-744. doi: 10.1109/ULTSYM.2014.0183. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/3sc6k2jx

© 2014 IEEE. A versatile silicon-based ultrasonic nebulizer that utilizes a twin-nozzle of multiple Fourier horns at 1-2 MHz drive frequencies has been realized to perform simultaneous aerosolization of cobinamide and magnesium thiosulfate drug solu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e9463165edd0aa329d441cbe9e8d2ac
http://www.escholarship.org/uc/item/3sc6k2jx

Hand-held high-throughput ultrasonic monodisperse aerosol inhalers for detoxification of massive cyanide poisoning

Autor: Steve Patterson, Sari B. Mahon, Shirley C. Tsai, Gerry R. Boss, Chen S. Tsai, Rong W. Mao, Eric Chien, Yun Zhu, James Maduzia, David Mukai, Tanya Berney, David Yoon, Matthew Brenner, Jangwoen Lee

Publikováno v: Tsai, CS; Mao, RW; Zhu, Y; Chien, E; Maduzia, J; Tsai, SC; et al.(2012). Hand-held high-throughput ultrasonic monodisperse aerosol inhalers for detoxification of massive cyanide poisoning. IEEE International Ultrasonics Symposium, IUS, 1632-1634. doi: 10.1109/ULTSYM.2012.0409. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/86m277hz

Detoxification of massive cyanide (CN) poisoning by inhalation of antidotes is recognized to be superior to intra venous (IV) or intra muscular (IM) treatment with regard to ease of administration, self-administration, and rapidity of onset. However,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2066ec22ad814be8d6817c84763e3032
http://www.escholarship.org/uc/item/86m277hz

Ejection of uniform micrometer-sized droplets from Faraday waves on a millimeter-sized water drop

Autor: Shirley C. Tsai, Chen S. Tsai, Shih K. Lin, Rong W. Mao

Publikováno v: Physical review letters. 108(15)

This Letter reports the first observation and theoretical analysis of a new phenomenon: one large spherical water drop ejecting simultaneously a very large number of monodisperse microdroplets. An ultrasonic nozzle with multiple-Fourier horns in reso

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fbd2feba3cf96fa9fe1c0b63547e506
https://pubmed.ncbi.nlm.nih.gov/22587258