Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Rong Lin Xie"'
Autor:
Jaime A. Rivera-Pérez, Andre J. van Wijnen, Jennifer L. Colby, Prachi N. Ghule, Stephen N. Jones, Gary S. Stein, Jane B. Lian, Rong Lin Xie, Janet L. Stein
Publikováno v:
Developmental Biology. 419:311-320
Fidelity of histone gene expression is important for normal cell growth and differentiation that is stringently controlled during development but is compromised during tumorigenesis. Efficient production of histones for packaging newly replicated DNA
Autor:
Peng-Fei Cui, Hu-Lin Jiang, Jian-Bin Qiao, Rong-Lin Xie, Feng-Zhen Wang, Bing-Feng Zhang, Mei Zhang, Jia-Liang Zhang, Lei Xing, Yu-Jing He, Jin-Yuan Lyu, Baoan Chen
Publikováno v:
Biomaterials. 61:178-189
The mitochondria-mediated apoptosis pathway is an effective option for cancer therapy due to the presence of cell-suicide weapons in mitochondria. However, anti-apoptotic proteins that are over-expressed in the mitochondria of many malignant tumors,
Autor:
Andre J. van Wijnen, Gary S. Stein, Ying Zhang, Jane B. Lian, Carlo M. Croce, Rong Lin Xie, Janet L. Stein
Publikováno v:
Proceedings of the National Academy of Sciences. 108:9863-9868
Lineage progression in osteoblasts and chondrocytes is stringently controlled by the cell-fate–determining transcription factor Runx2. In this study, we directly addressed whether microRNAs (miRNAs) can control the osteogenic activity of Runx2 and
Autor:
Yin Wenlin, Xiao-yi Pan, Hao Guijie, Wei-Qing Lu, Zheng Cao, Shen Jinyu, Rong-Lin Xie, Ying-Lei Wu
Publikováno v:
Acta Hydrobiologica Sinica. 33:338-341
Autor:
Gary S. Stein, Ricardo F. Medina, Rong Lin Xie, Andre J. Van Wijnen, Janet L. Stein, Angela Miele-Chamberland, Margaretha Van der Deen
Publikováno v:
Cancer Research. 67:10334-10342
HiNF-P and its cofactor p220NPAT are principal factors regulating histone gene expression at the G1-S phase cell cycle transition. Here, we have investigated whether HiNF-P controls other cell cycle– and cancer-related genes. We used cDNA microarra
Publikováno v:
Gene. 402:94-102
Histone nuclear factor P (HiNF-P) activates histone H4 gene transcription at the G1/S phase transition upon association with its cyclin E/CDK2 responsive co-factor p220 NPAT . Here we characterize the gene regulatory pathways that control the prolife
Autor:
Prachi N. Ghule, Jane B. Lian, Stephen N. Jones, Rong Lin Xie, Janet L. Stein, Andre J. Van Wijnen, Gary S. Stein, Jennifer L. Colby
Histone Nuclear Factor P (HINFP) is essential for expression of histone H4 genes. Ablation of Hinfp and consequential depletion of histones alter nucleosome spacing and cause stalled replication and DNA damage that ultimately result in genomic instab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18e4f06395a5daaa07a8f14ae21cb2bd
Autor:
J. Wade Harper, Andre J. Van Wijnen, Hayk Hovhannisyan, S. Kaleem Zaidi, Gary S. Stein, Yue Wei, Rong Lin Xie, Ricardo F. Medina, Janet L. Stein, Partha Mitra
Publikováno v:
Molecular and Cellular Biology. 23:8110-8123
At the G(1)/S phase cell cycle transition, multiple histone genes are expressed to ensure that newly synthesized DNA is immediately packaged as chromatin. Here we have purified and functionally characterized the critical transcription factor HiNF-P,
Publikováno v:
Advances in food and nutrition research. 73
Gene therapy involves the introduction of foreign genetic material into cells in order to exert a therapeutic effect. Successful gene therapy relies on effective vector system. Viral vectors are highly efficient in transfecting cells, but the undesir
Autor:
Bing-Feng Zhang, Rong-Lin Xie, Yoonjeong Jang, Peng-Fei Cui, Myung-Haing Cho, Hu-Lin Jiang, Lei Xing, Feng-Zhen Wang
Publikováno v:
International journal of pharmaceutics. 478(1)
The clinical successful application of gene therapy critically depends upon the development of non-toxic and efficient delivery system. Although polycationic non-viral vectors hold great promise in nanomedicine, the exploring of application in clinic