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Autor:
Sharon D. Ricardo, Rong Jiao Liang, James A. Deane, John F. Bertram, Naomi Vittoria Campanale, Jinhua Li
Publikováno v:
The American Journal of Pathology. 169:1527-1540
Inflammation and fibrogenesis are the two determinants of the progression of renal fibrosis, the common pathway leading to end-stage renal disease. The p38 mitogen-activated protein kinase (MAPK) and transforming growth factor (TGF)-beta1/Smad signal