Zobrazeno 1 - 10
of 147
pro vyhledávání: '"Rong, Chan"'
Autor:
Darren ZL Mok, Danny JH Tng, Jia Xin Yee, Valerie SY Chew, Christine YL Tham, Justin SG Ooi, Hwee Cheng Tan, Summer L Zhang, Lowell Z Lin, Wy Ching Ng, Lavanya Lakshmi Jeeva, Ramya Murugayee, Kelvin K-K Goh, Tze-Peng Lim, Liang Cui, Yin Bun Cheung, Eugenia Z Ong, Kuan Rong Chan, Eng Eong Ooi, Jenny G Low
Publikováno v:
EMBO Molecular Medicine, Vol 16, Iss 6, Pp 1310-1323 (2024)
Abstract Vaccination has successfully controlled several infectious diseases although better vaccines remain desirable. Host response to vaccination studies have identified correlates of vaccine immunogenicity that could be useful to guide developmen
Externí odkaz:
https://doaj.org/article/90c7121c4d0546eb8018f9ef0e765fd0
Autor:
Débora Dummer Meira, Aléxia Stefani Siqueira Zetum, Matheus Correia Casotti, Danielle Ribeiro Campos da Silva, Bruno Cancian de Araújo, Creuza Rachel Vicente, Daniel de Almeida Duque, Bianca Paulino Campanharo, Fernanda Mariano Garcia, Camilly Victória Campanharo, Carla Carvalho Aguiar, Carolina de Aquino Lapa, Flávio dos Santos Alvarenga, Henrique Perini Rosa, Luiza Poppe Merigueti, Marllon Cindra Sant’Ana, Clara W.T. Koh, Raquel Furlani Rocon Braga, Rahna Gonçalves Coutinho da Cruz, Rhana Evangelista Salazar, Vinícius do Prado Ventorim, Gabriel Mendonça Santana, Thomas Erik Santos Louro, Luana Santos Louro, Flavia Imbroisi Valle Errera, Flavia de Paula, Lorena Souza Castro Altoé, Lyvia Neves Rebello Alves, Raquel Silva dos Reis Trabach, Eldamária de Vargas Wolfgramm dos Santos, Elizeu Fagundes de Carvalho, Kuan Rong Chan, Iúri Drumond Louro
Publikováno v:
Heliyon, Vol 10, Iss 14, Pp e34393- (2024)
Since December 2019, a new form of Severe Acute Respiratory Syndrome (SARS) has emerged worldwide, caused by SARS coronavirus 2 (SARS-CoV-2). This disease was called COVID-19 and was declared a pandemic by the World Health Organization in March 2020.
Externí odkaz:
https://doaj.org/article/a6ae0b1c5da84082a3dd25841bdbb608
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract Gene expression profiling has helped tremendously in the understanding of biological processes and diseases. However, interpreting processed data to gain insights into biological mechanisms remain challenging, especially to the non-bioinform
Externí odkaz:
https://doaj.org/article/f7db75a967a341ccbd6a3972c85957a3
Autor:
Janessa Y.J. Tan, Danielle E. Anderson, Abhay P.S. Rathore, Aled O’Neill, Chinmay Kumar Mantri, Wilfried A.A. Saron, Cheryl Q.E. Lee, Chu Wern Cui, Adrian E.Z. Kang, Randy Foo, Shirin Kalimuddin, Jenny G. Low, Lena Ho, Paul Tambyah, Thomas W. Burke, Christopher W. Woods, Kuan Rong Chan, Jörn Karhausen, Ashley L. St. John
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 19 (2023)
Lung inflammation is a hallmark of Coronavirus disease 2019 (COVID-19) in patients who are severely ill, and the pathophysiology of disease is thought to be immune mediated. Mast cells (MCs) are polyfunctional immune cells present in the airways, whe
Externí odkaz:
https://doaj.org/article/0ded7096dad04c348c5c375637996e23
Publikováno v:
Bio-Protocol, Vol 13, Iss 16 (2023)
Lipids can play diverse roles in metabolism, signaling, transport across membranes, regulating body temperature, and inflammation. Some viruses have evolved to exploit lipids in human cells to promote viral entry, fusion, replication, assembly, and e
Externí odkaz:
https://doaj.org/article/11bcf86847d240e28c43102b32bc1901
Autor:
Eugenia Z. Ong, Jia Xin Yee, Justin S. G. Ooi, Ayesa Syenina, Ruklanthi de Alwis, Shiwei Chen, Jean X. Y. Sim, Shirin Kalimuddin, Yan Shan Leong, Yvonne F. Z. Chan, Rose Sekulovich, Brian M. Sullivan, Kelly Lindert, Sean B. Sullivan, Pad Chivukula, Steven G. Hughes, Jenny G. Low, Eng Eong Ooi, Kuan Rong Chan
Publikováno v:
npj Vaccines, Vol 7, Iss 1, Pp 1-9 (2022)
Abstract Remarkable potency has been demonstrated for mRNA vaccines in reducing the global burden of the ongoing COVID-19 pandemic. An alternative form of the mRNA vaccine is the self-amplifying mRNA (sa-mRNA) vaccine, which encodes an alphavirus rep
Externí odkaz:
https://doaj.org/article/f164a1f335254aad9b2305f3200a7da5
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-7 (2022)
Abstract Opening and processing gene expression data files in Excel runs into the inadvertent risk of converting gene names to dates. As pathway analysis tools rely on gene symbols to query against pathway databases, the genes that are converted to d
Externí odkaz:
https://doaj.org/article/d3bf0e05ac1344bbbdb5c8feac4b27df
Publikováno v:
Viruses, Vol 16, Iss 1, p 27 (2023)
Severe COVID-19 is a major cause of morbidity and mortality worldwide, especially among those with co-morbidities, the elderly, and the immunocompromised. However, the molecular determinants critical for severe COVID-19 progression remain to be fully
Externí odkaz:
https://doaj.org/article/74ee4c1c01c047cfa19f98885e74a8dd
Autor:
Shirin Kalimuddin, Yvonne F. Z. Chan, October M. Sessions, Kuan Rong Chan, Eugenia Z. Ong, Jenny G. Low, Antonio Bertoletti, Eng Eong Ooi
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Vaccination induces an adaptive immune response that protects against infectious diseases. A defined magnitude of adaptive immune response that correlates with protection from the disease of interest, or correlates of protection (CoP), is useful for
Externí odkaz:
https://doaj.org/article/4c9fd9a30d404461b2d2081e9e38a4e2
Autor:
Kuan Rong Chan, Clara W.T. Koh, Dorothy H.L. Ng, Shijie Qin, Justin S.G. Ooi, Eugenia Z. Ong, Summer L.X. Zhang, Huizhen Sam, Shirin Kalimuddin, Jenny G.H. Low, Eng Eong Ooi
Publikováno v:
EBioMedicine, Vol 89, Iss , Pp 104472- (2023)
Summary: Background: Mass vaccination has dramatically reduced the incidence of severe COVID-19, with most cases now presenting as self-limiting upper respiratory tract infections. However, those with co-morbidities, the elderly and immunocompromised
Externí odkaz:
https://doaj.org/article/70461e7192624ff09b631c2b2187ac19