Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Ronen Schuster"'
Autor:
Alon Gimmon, Lior Sherker, Lena Kojukarov, Melodie Zaknoun, Yotam Lior, Tova Fadel, Ronen Schuster, Eli C. Lewis, Eldad Silberstein
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 13, p 7364 (2022)
Wound healing requires a non-compromising combination of inflammatory and anti-inflammatory processes. Human α1-antitrypsin (hAAT), a circulating glycoprotein that rises during acute-phase responses and during healthy pregnancies, is tissue-protecti
Externí odkaz:
https://doaj.org/article/6e0d41351a664ed0a8517c5dadd8b8d0
Autor:
Ziv Kaner, Rotem Engelman, Ronen Schuster, Peleg Rider, David Greenberg, Yossef Av-Gay, Moran Benhar, Eli C. Lewis
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Background: Human α1-antitrypsin (hAAT) is a circulating anti-inflammatory serine-protease inhibitor that rises during acute phase responses. in vivo, hAAT reduces bacterial load, without directly inhibiting bacterial growth. In conditions of excess
Externí odkaz:
https://doaj.org/article/3d9bd825ade54ac09780d1d4b599b443
Autor:
Yotam Lior, Mariana Zaretsky, David E. Ochayon, Diana Lotysh, Boris M. Baranovski, Ronen Schuster, Ofer Guttman, Amir Aharoni, Eli C. Lewis
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
IntroductionHuman α1-antitrypsin (hAAT) is a 394-amino acid long anti-inflammatory, neutrophil elastase inhibitor, which binds elastase via a sequence-specific molecular protrusion (reactive center loop, RCL; positions 357–366). hAAT formulations
Externí odkaz:
https://doaj.org/article/485d78fe6906435d902fe3ccf61c2442
Autor:
David E. Ochayon, Boris M. Baranovski, Peter Malkin, Ronen Schuster, Noa Kalay, Rotem Ben-Hamo, Ido Sloma, Justin Levinson, Jared Brazg, Sol Efroni, Eli C. Lewis, Uri Nevo
Publikováno v:
Cell Transplantation, Vol 25 (2016)
Immune tolerance toward “self” is critical in multiple immune disorders. While there are several mechanisms to describe the involvement of immune cells in the process, the role of peripheral tissue cells in that context is not yet clear. The theo
Externí odkaz:
https://doaj.org/article/8c074e7b554446628cf5b9dae397d835
Autor:
Maya Ezzo, Nuno M. Coelho, Stellar Boo, Sander van Putten, David W. Griggs, Boris Hinz, Christopher A. McCulloch, Nina Noskovičová, Ronen Schuster, Peter G. Ruminski, Anne Koehler
Publikováno v:
Nature Biomedical Engineering. 5:1437-1456
The fibrotic encapsulation of implants involves the mechanical activation of myofibroblasts and of pro-fibrotic transforming growth factor beta 1 (TGF-β1). Here, we show that both softening of the implant surfaces and inhibition of the activation of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::005d92d382f815aae7f280c7eb3f9ade
https://doi.org/10.1038/s41551-021-00722-z
https://doi.org/10.1038/s41551-021-00722-z
Publikováno v:
Immunological Reviews. 302:126-146
Activation of fibroblasts is a key event during normal tissue repair after injury and the dysregulated repair processes that result in organ fibrosis. To most researchers, fibroblasts are rather unremarkable spindle-shaped cells embedded in the fibro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e1167a64ce893b872d753b2bc772f6b
https://doi.org/10.1111/imr.12971
https://doi.org/10.1111/imr.12971
Autor:
Hagit Cohen, Roni Gillis, Eran Levanon, Yoram Etzion, Wesam Mulla, Dor Danan, Hadar Klapper-Goldstein, Sigal Elyagon, Ronen Schuster, Michael Murninkas
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
Scientific Reports
Scientific Reports
Atrial fibrillation (AF) is a progressive arrhythmia with underlying mechanisms that are not fully elucidated, partially due to lack of reliable and affordable animal models. Here, we introduce a system for long-term assessment of AF susceptibility (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f4d20cc34ba7f95adbaaa613e38091b
http://link.springer.com/article/10.1038/s41598-020-57528-3
http://link.springer.com/article/10.1038/s41598-020-57528-3
Publikováno v:
Cold Spring Harbor Perspectives in Biology. 15:a041231
Myofibroblasts are the construction workers of wound healing and repair damaged tissues by producing and organizing collagen/extracellular matrix (ECM) into scar tissue. Scar tissue effectively and quickly restores the mechanical integrity of lost ti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73d45a26af740272b7f92ec8609b0b1d
https://doi.org/10.1101/cshperspect.a041231
https://doi.org/10.1101/cshperspect.a041231
Publikováno v:
Advances in Wound Care. 8:281-290
Objective: Skin flaps are routinely used in reconstructive surgery yet remain susceptible to ischemia and necrosis. Distant flaps require lengthy time to detach causing patient discomfort. Human α1-antitrypsin (hAAT) is a clinically available serum
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70e1620924d5c715a19bbc5dc4bd85f9
https://doi.org/10.1089/wound.2018.0889
https://doi.org/10.1089/wound.2018.0889
Publikováno v:
Bioinformatics
Motivation The effectiveness of drugs tends to vary between patients. One of the well-known reasons for this phenomenon is genetic polymorphisms in drug target genes among patients. Here, we propose that differences in expression levels of drug targe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::180b1da2c0b09aedf328adb16a28916d
https://doi.org/10.1093/bioinformatics/btz023
https://doi.org/10.1093/bioinformatics/btz023