Zobrazeno 1 - 10
of 79
pro vyhledávání: '"Ronan Le-Goffic"'
Autor:
Elliot Mathieu, Quentin Marquant, Florian Chain, Edwige Bouguyon, Vinciane Saint-Criq, Ronan Le-Goffic, Delphyne Descamps, Philippe Langella, Thomas A. Tompkins, Sylvie Binda, Muriel Thomas
Publikováno v:
Nutrients, Vol 15, Iss 2, p 263 (2023)
Microbiota studies have dramatically increased over these last two decades, and the repertoire of microorganisms with potential health benefits has been considerably enlarged. The development of next generation probiotics from new bacterial candidate
Externí odkaz:
https://doaj.org/article/75a370a84ba04394bbf68073efbe63a8
Autor:
Cynthia Calzas, Tamiru N. Alkie, Matthew Suderman, Carissa Embury-Hyatt, Vinay Khatri, Ronan Le Goffic, Yohannes Berhane, Steve Bourgault, Denis Archambault, Christophe Chevalier
Publikováno v:
npj Vaccines, Vol 9, Iss 1, Pp 1-13 (2024)
Abstract Current poultry vaccines against influenza A viruses target the globular head region of the hemagglutinin (HA1), providing limited protection against antigenically divergent strains. Experimental subunit vaccines based on the conserved ectod
Externí odkaz:
https://doaj.org/article/204c6c5af4c74caf9732f1dfd3dcefd7
Autor:
Svenja M. Sake, Xiaoyu Zhang, Manoj Kumar Rajak, Melanie Urbanek-Quaing, Arnaud Carpentier, Antonia P. Gunesch, Christina Grethe, Alina Matthaei, Jessica Rückert, Marie Galloux, Thibaut Larcher, Ronan Le Goffic, Fortune Hontonnou, Arnab K. Chatterjee, Kristen Johnson, Kaycie Morwood, Katharina Rox, Walid A. M. Elgaher, Jiabin Huang, Martin Wetzke, Gesine Hansen, Nicole Fischer, Jean-Francois Eléouët, Marie-Anne Rameix-Welti, Anna K. H. Hirsch, Elisabeth Herold, Martin Empting, Chris Lauber, Thomas F. Schulz, Thomas Krey, Sibylle Haid, Thomas Pietschmann
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Respiratory syncytial virus (RSV) is a common cause of acute lower respiratory tract infection in infants, older adults and the immunocompromised. Effective directly acting antivirals are not yet available for clinical use. To address this,
Externí odkaz:
https://doaj.org/article/66d08a2bbc3740f4a9e811166d229bd4
Autor:
Stéphane Biacchesi, Christophe Chevalier, Marie Galloux, Christelle Langevin, Ronan Le Goffic, Michel Brémont
Grippe, rougeole, gastro-entérite… Tout au long de notre vie, des virus croisent régulièrement notre route. D'autres, comme Zika, H1N1 et Ebola, font la une des journaux, en émergeant ou en ré-émergeant soudainement. D'où viennent-ils? Pourq
Autor:
Joëlle Mettier, Daniel Marc, Laura Sedano, Bruno Da Costa, Christophe Chevalier, Ronan Le Goffic
Publikováno v:
Virulence, Vol 12, Iss 1, Pp 1647-1660 (2021)
Influenza A viruses cause important diseases in both human and animal. The PB1-F2 protein is a virulence factor expressed by some influenza viruses. Its deleterious action for the infected host is mostly described in mammals, while the available info
Externí odkaz:
https://doaj.org/article/5e695070b82f4788b25faf81a691e381
Autor:
Olivier Terrier, Mustapha Si-Tahar, Mariette Ducatez, Christophe Chevalier, Andrés Pizzorno, Ronan Le Goffic, Thibaut Crépin, Gaëlle Simon, Nadia Naffakh
Publikováno v:
PLoS Pathogens, Vol 17, Iss 12, p e1010106 (2021)
The development of safe and effective vaccines in a record time after the emergence of the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) is a remarkable achievement, partly based on the experience gained from multiple viral outbreaks i
Externí odkaz:
https://doaj.org/article/566ace5a1d7d4dc993a8e76ff33bff7a
Autor:
Cynthia Calzas, Molida Mao, Mathilde Turpaud, Quentin Viboud, Joelle Mettier, Thomas Figueroa, Pierre Bessière, Antoine Mangin, Laura Sedano, Pierre-Louis Hervé, Romain Volmer, Mariette F. Ducatez, Steve Bourgault, Denis Archambault, Ronan Le Goffic, Christophe Chevalier
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Current inactivated vaccines against influenza A viruses (IAV) mainly induce immune responses against highly variable epitopes across strains and are mostly delivered parenterally, limiting the development of an effective mucosal immunity. In this st
Externí odkaz:
https://doaj.org/article/ce5eeb8fd4fc4f3c89ecec190951fa7b
Autor:
Valentin Sencio, Adeline Barthelemy, Luciana P. Tavares, Marina G. Machado, Daphnée Soulard, Céline Cuinat, Celso Martins Queiroz-Junior, Marie-Louise Noordine, Sophie Salomé-Desnoulez, Lucie Deryuter, Benoit Foligné, Céline Wahl, Benoit Frisch, Angelica T. Vieira, Christophe Paget, Graeme Milligan, Trond Ulven, Isabelle Wolowczuk, Christelle Faveeuw, Ronan Le Goffic, Muriel Thomas, Stéphanie Ferreira, Mauro M. Teixeira, François Trottein
Publikováno v:
Cell Reports, Vol 30, Iss 9, Pp 2934-2947.e6 (2020)
Summary: Secondary bacterial infections often complicate viral respiratory infections. We hypothesize that perturbation of the gut microbiota during influenza A virus (IAV) infection might favor respiratory bacterial superinfection. Sublethal infecti
Externí odkaz:
https://doaj.org/article/09663ef56a7e41888b718db1c3193a50
Publikováno v:
Journal of Spectral Imaging, Vol 8, p a18 (2019)
PB1-F2 is a non-structural protein of influenza A viruses (IAV) that modulates viral pathogenesis in a host-specific manner. In mammals, this protein has been shown to increase IAV virulence by delaying the early immune response and, eventually, exac
Externí odkaz:
https://doaj.org/article/1a0c763b91c6454dac7a86df5303c003
Autor:
Joëlle Mettier, Clémentine Prompt, Elise Bruder, Bruno Da Costa, Christophe Chevalier, Ronan Le Goffic
Publikováno v:
Viruses
Volume 15
Issue 2
Pages: 328
Volume 15
Issue 2
Pages: 328
Most influenza viruses express the PB1-F2 protein which is regarded as a virulence factor. However, PB1-F2 behaves differently in avian and mammalian hosts, suggesting that this protein may be involved in the species barrier crossings regularly obser