Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Ronan Bergin"'
Autor:
Fiachra Humphries, Ronan Bergin, Ruaidhri Jackson, Nezira Delagic, Bingwei Wang, Shuo Yang, Alice V. Dubois, Rebecca J. Ingram, Paul N. Moynagh
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-17 (2018)
The NLRP3 inflammasome is important for inducing IL-1β and IL-18 inflammatory responses. Here the authors show, by generating and characterizing Peli2 deficient mice and immune cells, that an E3 ubiquitin ligase Pellino2 promotes inflammasome primin
Externí odkaz:
https://doaj.org/article/b58516ad7891424abe4c474bec6c5209
Autor:
Nidhi Kedia-Mehta, Marta M. Pisarska, Christina Rollings, Chloe O’Neill, Conor De Barra, Cathriona Foley, Nicole A. W. Wood, Neil Wrigley-Kelly, Natacha Veerapen, Gurdyal Besra, Ronan Bergin, Nicholas Jones, Donal O’Shea, Linda V. Sinclair, Andrew E. Hogan
Mucosal-associated invariant T (MAIT) cells are an abundant population of innate T cells that recognize bacterial ligands and play a key role in host protection against bacterial and viral pathogens. Upon activation, MAIT cells undergo proliferative
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71306b3d72d96f9b4cb02d51fc6dc1fc
https://cronfa.swan.ac.uk/Record/cronfa63256
https://cronfa.swan.ac.uk/Record/cronfa63256
Autor:
Féaron C. Cassidy, Nidhi Kedia-Mehta, Ronan Bergin, Andrea Woodcock, Ardena Berisha, Ben M. Bradley, Eva Booth, Odhran K. Ryan, Linda V. Sinclair, Donal O’Shea, Andrew E. Hogan
Mucosal Associated Invariant T (MAIT) cells are a subset of unconventional T cells, which recognise a limited repertoire of ligands presented by the MHC class I-like molecule MR1. In addition to their key role in host protection against bacterial and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::97ab0b61713dc617c83f1b28fb021e28
https://doi.org/10.1101/2022.12.20.521164
https://doi.org/10.1101/2022.12.20.521164
Autor:
Nidhi Kedia-Mehta, Marta M. Pisarska, Christina Rollings, Chloe O’Neill, Conor De Barra, Cathriona Foley, Nicole AW. Wood, Neil Wrigley-Kelly, Natacha Veerapen, Gurdyal Besra, Ronan Bergin, Nicholas Jones, Donal O’Shea, Linda V. Sinclair, Andrew E. Hogan
Mucosal Associated Invariant T (MAIT) cells are an abundant population of innate T cells which recognise bacterial ligands presented by the MHC class-I like molecule MR1. MAIT cells play a key role in host protection against bacterial and viral patho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1568ee5338eb9bd23b896c6a558849e9
https://doi.org/10.1101/2022.01.17.476571
https://doi.org/10.1101/2022.01.17.476571
Autor:
Ronan Bergin, David Kinlen, Nidhi Kedia-Mehta, Eadaoin Hayes, Féaron C. Cassidy, Declan Cody, Donal O’Shea, Andrew E. Hogan
Publikováno v:
Diabetologia. 65(6)
Aims/hypothesis Mucosal-associated invariant T cells (MAIT cells) are an abundant population of innate T cells. When activated, MAIT cells rapidly produce a range of cytokines, including IFNγ, TNF-α and IL-17. Several studies have implicated MAIT c
Autor:
Ronan Bergin, Natacha Veerapen, Donal O'Shea, Cathriona Foley, Andrew E. Hogan, Gurdyal S. Besra, Frances C. Tinley, Róisín M. Loftus, Marta M. Pisarska, Arimin Mat, Laura Tobin, Ciaran Bannan, Paul N. Moynagh, Gary Sommerville, Linda V. Sinclair, Aisling M. O'Brien, David K. Finlay, Lydia Lynch, Nicole A. W. Wood
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 202(12)
Obesity underpins the development of numerous chronic diseases, such as type II diabetes mellitus. It is well established that obesity negatively alters immune cell frequencies and functions. Mucosal-associated invariant T (MAIT) cells are a populati
Publikováno v:
Stem Cells and Development. 24:2391-2402
The immune suppressive and anti-inflammatory capabilities of bone marrow-derived mesenchymal stromal cells (MSCs) represent an innovative new tool in regenerative medicine and immune regulation. The potent immune suppressive ability of MSC over T cel
Autor:
Alan Horgan, Wolfgang Wurst, John J. Callanan, Thomas Floss, Mark Mellett, Paul N. Moynagh, Paola Atzei, Ronan Bergin
Publikováno v:
Nature Communications. 6
Receptor families of the innate immune response engage in 'cross-talk' to tailor optimal immune responses against invading pathogens. However, these responses are subject to multiple levels of regulation to keep in check aberrant inflammatory signals
Autor:
Ruaidhri Jackson, Shuo Yang, Fergus Shanahan, Aoife Quinlan, Barry Hall, Gabriella Aviello, Padraic G. Fallon, Silvia Melgar, Ronan Bergin, Fiachra Humphries, Marc E. Healy, Paul N. Moynagh, Bingwei Wang, Deirdre McNamara, Trevor Darby
Publikováno v:
Nature immunology. 14(9)
Mutations that result in loss of function of Nod2, an intracellular receptor for bacterial peptidoglycan, are associated with Crohn’s disease. Here we found that the E3 ubiquitin ligase Pellino3 was an important mediator in the Nod2 signaling pathw
Publikováno v:
Daily Mail. 8/22/2016, p23. 1p.