Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Ronaldo Medeiros Golombieski"'
Autor:
Ronaldo Medeiros Golombieski, Daniel Ângelo Sgranzerla Graichen, João Batista Teixeira da Rocha, Vera Lúcia da Silva Valente, Élgion Lúcio da Silva Loreto
Publikováno v:
Genetics and Molecular Biology, Vol 31, Iss 1, Pp 128-135 (2008)
Selenium is an important dietary micronutrient and an essential component of selenoproteins and the active sites of some enzymes, although at high concentrations it is toxic. We investigated diphenyl diselenide ((C6H5)2Se2 ) for its effects on the de
Externí odkaz:
https://doaj.org/article/904db423ccae480f90a9714d946bcd0c
Autor:
Félix Alexandre Antunes Soares, Michele Rechia Fighera, Luiz Fernando Freire Royes, Fernando Dobrachinski, Rodrigo A. Cunha, Lisiane O. Porciúncula, Alfredo Q. Antoniazzi, Cristina W. Nogueira, Rogério da Rosa Gerbatin, Gláubia Sartori, Ronaldo Medeiros Golombieski
Publikováno v:
Molecular neurobiology. 56(5)
Traumatic brain injury (TBI) is a leading cause of disability worldwide, triggering chronic neurodegeneration underlying cognitive and mood disorder still without therapeutic prospects. Based on our previous observations that guanosine (GUO) attenuat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::582dbb79f30fe6a9662b481d7811ae98
https://pubmed.ncbi.nlm.nih.gov/30105669
https://pubmed.ncbi.nlm.nih.gov/30105669
Autor:
Cristiane Lenz Dalla Corte, Nelson Rodrigues de Carvalho, Fernando Dobraschinski, Guilherme Pires Amaral, Ana Paula Pegoraro Zemolin, Félix Alexandre Antunes Soares, Javier González-Gallego, José L. Mauriz, Ronaldo Medeiros Golombieski, Cintia C. Tassi, Jeferson Luis Franco
Publikováno v:
Life sciences. 180
Physiopathological conditions such as acute liver failure (ALF) induced by acetaminophen (APAP) can often impair the mitochondrial bioenergetics. Diphenyl diselenide [(PhSe)2] has been shown protects against APAP-induced ALF. The present study aimed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c060eed34643823969b1fc6ae2a297d5
https://pubmed.ncbi.nlm.nih.gov/28501483
https://pubmed.ncbi.nlm.nih.gov/28501483
Autor:
Raquel Cristine Silva Barcelos, Katiane Roversi, Camila Simonetti Pase, Juliana C. Veit, Fábio Teixeira Kuhn, Jaqueline Piccolo, Ronaldo Medeiros Golombieski, Verônica Tironi Dias, Fabíola Trevizol, Karine Roversi, Marilise Escobar Burger, Tatiana Emanuelli, João Rocha
Publikováno v:
Hippocampus. 25:556-565
Recently, we have described the influence of dietary fatty acids (FA) on mania-like behavior of first generation animals. Here, two sequential generations of female rats were supplemented with soybean oil (SO, rich in n-6 FA, control group), fish oil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b83d2907cb1a65a04b02668341713def
https://doi.org/10.1002/hipo.22391
https://doi.org/10.1002/hipo.22391
Autor:
João Rocha, Fernando Dobrachinski, Élgion Lúcio da Silva Loreto, Cintia C. Tassi, Nelson Rodrigues de Carvalho, Michele Rechia Fighera, Ronaldo Medeiros Golombieski, Glaecir Roseni Mundstock Dias, Félix Alexandre Antunes Soares, Michele Hinerasky da Silva
Publikováno v:
Neurotoxicity Research. 26:317-330
Acute stroke is a major risk for morbidity and mortality in aging population. Mitochondrion has been the focus of a wide stroke-related research. This study investigated if treatment or pre-treatment with diphenyl diselenide (PhSe)2 can prevent mitoc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::828b77ec1c5514a8b3a0a135456b8106
https://doi.org/10.1007/s12640-014-9463-2
https://doi.org/10.1007/s12640-014-9463-2
Autor:
Guilherme Pires Amaral, João Rocha, Cristina W. Nogueira, Rafael de Lima Portella, Glaecir Roseni Mundstock Dias, Félix Alexandre Antunes Soares, Nilda Vargas Barbosa, Ronaldo Medeiros Golombieski
Publikováno v:
Neuroendocrinology. 100:45-59
Introduction: Cellular antioxidant signaling can be altered either by thyroid disturbances or by selenium status. Aims: To investigate whether or not dietary diphenyl diselenide can modify the expression of genes of antioxidant enzymes and endpoint m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::864c1048e117c36ed638b543c1108775
https://doi.org/10.1159/000365515
https://doi.org/10.1159/000365515
Autor:
Ronaldo Medeiros Golombieski, Ana Paula Pegoraro Zemolin, Ana Paula Fleig Saidelles, Thomas J.S. Merritt, Thaís Posser, Erico M.M. Flores, João Rocha, Antonio Batista Pereira, Rochele S. Picoloto, Élgion Lúcio da Silva Loreto, Jeferson Luis Franco, Mariane Trindade de Paula, Alessandra Pinto Vargas
Publikováno v:
Environmental Toxicology. 29:621-630
The heavy metal mercury is a known toxin, but while the mechanisms involved in mercury toxicity have been well demonstrated in vertebrates, little is known about toxicological effects of this metal in invertebrates. Here, we present the results of ou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::02a9b9c952f1e7e48506ab8ed48b5824
https://doi.org/10.1002/tox.21788
https://doi.org/10.1002/tox.21788
Autor:
João Rocha, Lucinéia A. Pivetta, Élgion Lúcio da Silva Loreto, D.A.S. Graichen, Ronaldo Medeiros Golombieski, Cristina W. Nogueira
Publikováno v:
Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology. 147:198-204
The main objective of the present study was to compare the inhibitory effect of diphenyl diselenide (PhSe)(2) and Pb(2+) on mice and fruit fly delta-Aminolevulinate dehydratase (delta-ALA-D). Optimum pH was quite different for mice (pH 6.5) and flies
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7352990f6554d6cc2ff8b9af6291a3a
https://doi.org/10.1016/j.cbpc.2007.09.007
https://doi.org/10.1016/j.cbpc.2007.09.007
Autor:
Camila Simonetti Pase, Marilise Escobar Burger, Katiane Roversi, Fabíola Trevizol, Verônica Tironi Dias, Ronaldo Medeiros Golombieski, Tatiana Emanuelli, Fabio T. Kunh, Raquel Cristine Silva Barcelos, Alessandra J. Schuster, Karine Roversi
Publikováno v:
Brain research bulletin. 118
Purpose To evaluate the toxicity of chronic consumption of processed foods that are rich in trans fat on the lipid composition of brain membranes, as well as its functional repercussions. Methods A second generation of male rats born from mothers and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90abfdf20e6308dc71d7dbbb1042dd3e
https://pubmed.ncbi.nlm.nih.gov/26393778
https://pubmed.ncbi.nlm.nih.gov/26393778
Autor:
D.C. Zamberlan, Leticia Priscilla Arantes, Félix Alexandre Antunes Soares, Ronaldo Medeiros Golombieski, Marina Lopes Machado
Publikováno v:
Neuroscience. 278
Alzheimer's disease (AD) is the most common and devastating neurodegenerative disease. The etiology of AD has yet to be fully understood, and common treatments remain largely non-efficacious. The amyloid hypothesis posits that extracellular amyloid-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50e2279407b46c86e13eb459f5e0c42c
https://pubmed.ncbi.nlm.nih.gov/25130558
https://pubmed.ncbi.nlm.nih.gov/25130558