Výsledky vyhledávání - "Ronaldo J. F. C. do Amaral"

Akademický článek

Functionalising Collagen-Based Scaffolds With Platelet-Rich Plasma for Enhanced Skin Wound Healing Potential

Autor: Ronaldo J. F. C. do Amaral, Noora M. A. Zayed, Elena I. Pascu, Brenton Cavanagh, Chris Hobbs, Francesco Santarella, Christopher R. Simpson, Ciara M. Murphy, Rukmani Sridharan, Arlyng González-Vázquez, Barry O'Sullivan, Fergal J. O'Brien, Cathal J. Kearney

Publikováno v: Frontiers in Bioengineering and Biotechnology, Vol 7 (2019)

Porous collagen-glycosaminoglycan (collagen-GAG) scaffolds have shown promising clinical results for wound healing; however, these scaffolds do not replace the dermal and epidermal layer simultaneously and rely on local endogenous signaling to direct

Externí odkaz: https://doaj.org/article/0000d991955d4a609af16f641fffc949

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Akademický článek

Infrapatellar Fat Pad Stem Cells: From Developmental Biology to Cell Therapy

Autor: Ronaldo J. F. C. do Amaral, Henrique V. Almeida, Daniel J. Kelly, Fergal J. O’Brien, Cathal J. Kearney

Publikováno v: Stem Cells International, Vol 2017 (2017)

The ideal cell type to be used for cartilage therapy should possess a proven chondrogenic capacity, not cause donor-site morbidity, and should be readily expandable in culture without losing their phenotype. There are several cell sources being inves

Externí odkaz: https://doaj.org/article/24c06f8df1504bf7aa8f143d6cce99bc

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Polyesters with main and side chain phosphoesters as structural motives for biocompatible electrospun fibres

Autor: Brian Gorey, Viviane Chiaradia, Claudia Sayer, Débora de Oliveira, Cathal J. Kearney, Pedro Henrique Hermes de Araújo, José Vladimir de Oliveira, Andreas Heise, André E. Polloni, Ronaldo J F C do Amaral

Publikováno v: Articles

Phosphoester containing polymers are promising materials in biomedical applications due to their biocompatibility and biodegradability. Utilising thiol-ene chemistry, the synthesis of two novel structural polymer motives combining polyesters and phop

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97616dc9cd488e92e22287e431e19914
https://doi.org/10.1039/d0py00033g

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Proteomic Analysis of HCC-1954 and MCF-7 Cell Lines Highlights Crosstalk between αv and β1 Integrins, E-Cadherin and HER-2

Autor: Denise de Abreu Pereira, Vanessa Sandim, Thais F. B. Fernandes, Vitor Hugo Almeida, Murilo Ramos Rocha, Ronaldo J. F. C. do Amaral, Maria Isabel D. Rossi, Dário Eluan Kalume, Russolina B. Zingali

Publikováno v: International Journal of Molecular Sciences; Volume 23; Issue 17; Pages: 10194

Overexpression of human epidermal growth factor receptor-2 (HER-2) occurs in 20% of all breast cancer subtypes, especially those that present the worst prognostic outcome through a very invasive and aggressive tumour. HCC-1954 (HER-2+) is a highly in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73b1c2b419b3c93964dbe788723af60f
https://pubmed.ncbi.nlm.nih.gov/36077593

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3D-printed gelatin methacrylate scaffolds with controlled architecture and stiffness modulate the fibroblast phenotype towards dermal regeneration

Autor: Fergal J. O'Brien, Alexandra P. Marques, Ronaldo J F C do Amaral, Rita I. R. Ibanez, Ciara M. Murphy, Rui L. Reis

Publikováno v: Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Polymers
Polymers, Vol 13, Iss 2510, p 2510 (2021)
Volume 13
Issue 15

Impaired skin wound healing due to severe injury often leads to dysfunctional scar tissue formation as a result of excessive and persistent myofibroblast activation, characterised by the increased expression of α-smooth muscle actin (αSMA) and extr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5a60d41072465b6459f12477f11378e

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Versatility of unsaturated polyesters from electrospun macrolactones: RGD immobilization to increase cell attachment

Autor: Cathal J. Kearney, Cian Cummins, Fernando Cabral Sales de Oliveira, Luiza Erthal Cardoso Dos Santos, Michael M. Morris, Andreas Heise, Ronaldo J F C do Amaral

Publikováno v: Journal of biomedical materials research. Part AREFERENCES. 110(2)

Poly(globalide) (PGl), an aliphatic polyester derived from unsaturated macrocylic lactone, can be cross-linked during electrospinning and drug-loaded for regenerative medicine applications. However, it lacks intrinsic recognition sites for cell adhes

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c72ba157a4f3ed7732748ef143ad72a5
https://pubmed.ncbi.nlm.nih.gov/34322978

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Development of wound healing scaffolds with precisely-triggered sequential release of therapeutic nanoparticles

Autor: Catherine Sirafim, Shin-Loong Soong, Renuka Sitram, Sean McGrath, Tauseef Ahmad, Cathal J. Kearney, Francesco Santarella, Shifa'a Turkistani, Ronaldo J F C do Amaral

Publikováno v: Biomaterials Science

Natural bioactive cue profiles are generally transient with cues switching on/off to coordinate successful outcomes. Dysregulation of these sequences typically leads to disease. Successful wound healing, for example, should progress sequentially thro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c84149d94ba5c1bb53c6aad1c261a117
https://pubmed.ncbi.nlm.nih.gov/33226390

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Synthesis of bilayer films from regenerated cellulose nanofibers and poly(globalide) for skin tissue engineering applications

Autor: Andreas Heise, Cathal J. Kearney, Fernando de Oliveira, James A. Wilson, Heliane R. Amaral, Jair C. C. Freitas, Ronaldo J F C do Amaral, Irina Pascu

Publikováno v: Carbohydrate polymers. 252

Commercial cell-based skin regenerative products are highly expensive, carry the risk of rejection and require a long cell culture period to manufacture. This work describes the synthesis of bilayer films from poly(globalide) (PGl) and regenerated ce

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e374bf58fe8ed426c174dc63cf729e8c
https://pubmed.ncbi.nlm.nih.gov/33183637

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PD27-08 DEVELOPMENT AND INVESTIGATION OF A TISSUE-ENGINEERED BIODEGRADABLE MESH FOR THE TREATMENT OF STRESS URINARY INCONTINENCE (SUI) IN FEMALE PATIENTS

Autor: Niall F. Davis, Michael Joyce, Eoin MacCraith, Eoghan M. Cunnane, Fergal J. O'Brien, Ronaldo J F C do Amaral

Publikováno v: Journal of Urology. 203

INTRODUCTION AND OBJECTIVE:Surgical polypropylene mesh is a material that can be used to treat pelvic organ prolapse and stress urinary incontinence. Mesh is made from non-absorbable polypropylene ...

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::fa09afb1619e31886ada99c7d948d83c
https://doi.org/10.1097/ju.0000000000000884.08

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Scaffolds Functionalized with Matrix from Induced Pluripotent Stem Cell Fibroblasts for Diabetic Wound Healing

Autor: Fergal J. O'Brien, Rukmani Sridharan, Olga Kashpur, Francesco Santarella, Behzad Gerami-Naini, Milica Marinkovic, Ronaldo J F C do Amaral, Jonathan A. Garlick, Cathal J. Kearney, Avi Smith, Brenton Cavanagh

Publikováno v: Advanced healthcare materials. 9(16)

Diabetic foot ulcers (DFUs) are chronic wounds, with 20% of cases resulting in amputation, despite intervention. A recently approved tissue engineering product-a cell-free collagen-glycosaminoglycan (GAG) scaffold-demonstrates 50% success, motivating

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3473d7c34cb6ffe6fa3ee409252d7405
https://pubmed.ncbi.nlm.nih.gov/32597577

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