Zobrazeno 1 - 10
of 71
pro vyhledávání: '"Ronaldo F Enriquez"'
Autor:
Ee-Cheng Khor, Bruce Fanshawe, Yue Qi, Sergei Zolotukhin, Rishikesh N Kulkarni, Ronaldo F Enriquez, Louise Purtell, Nicola J Lee, Natalie K Wee, Peter I Croucher, Lesley Campbell, Herbert Herzog, Paul A Baldock
Publikováno v:
PLoS ONE, Vol 11, Iss 1, p e0148155 (2016)
Prader-Willi Syndrome (PWS), a maternally imprinted disorder and leading cause of obesity, is characterised by insatiable appetite, poor muscle development, cognitive impairment, endocrine disturbance, short stature and osteoporosis. A number of caus
Externí odkaz:
https://doaj.org/article/707580c41569469e85e0b7d18109c9b5
Intermittent Moderate Energy Restriction Improves Weight Loss Efficiency in Diet-Induced Obese Mice.
Autor:
Radhika V Seimon, Yan-Chuan Shi, Katy Slack, Kailun Lee, Hamish A Fernando, Amy D Nguyen, Lei Zhang, Shu Lin, Ronaldo F Enriquez, Jackie Lau, Herbert Herzog, Amanda Sainsbury
Publikováno v:
PLoS ONE, Vol 11, Iss 1, p e0145157 (2016)
BACKGROUND:Intermittent severe energy restriction is popular for weight management. To investigate whether intermittent moderate energy restriction may improve this approach by enhancing weight loss efficiency, we conducted a study in mice, where ene
Externí odkaz:
https://doaj.org/article/c9ff58a567ad48899d22a5a9fc9bfeec
Autor:
Elysse C. Filipe, Sipiththa Velayuthar, Ashleigh Philp, Max Nobis, Sharissa L. Latham, Amelia L. Parker, Kendelle J. Murphy, Kaitlin Wyllie, Gretel S. Major, Osvaldo Contreras, Ellie T. Y. Mok, Ronaldo F. Enriquez, Suzanne McGowan, Kristen Feher, Lake‐Ee Quek, Sarah E. Hancock, Michelle Yam, Emmi Tran, Yordanos F. I. Setargew, Joanna N. Skhinas, Jessica L. Chitty, Monica Phimmachanh, Jeremy Z. R. Han, Antonia L. Cadell, Michael Papanicolaou, Hadi Mahmodi, Beata Kiedik, Simon Junankar, Samuel E. Ross, Natasha Lam, Rhiannon Coulson, Jessica Yang, Anaiis Zaratzian, Andrew M. Da Silva, Michael Tayao, Ian L. Chin, Aurélie Cazet, Maya Kansara, Davendra Segara, Andrew Parker, Andrew J. Hoy, Richard P. Harvey, Ozren Bogdanovic, Paul Timpson, David R. Croucher, Elgene Lim, Alexander Swarbrick, Jeff Holst, Nigel Turner, Yu Suk Choi, Irina V. Kabakova, Andrew Philp, Thomas R. Cox
Publikováno v:
Advanced Science, Vol 11, Iss 23, Pp n/a-n/a (2024)
Abstract In recent decades, the role of tumor biomechanics on cancer cell behavior at the primary site has been increasingly appreciated. However, the effect of primary tumor biomechanics on the latter stages of the metastatic cascade, such as metast
Externí odkaz:
https://doaj.org/article/9b5a588e6e1648e795ea8f0708ede5c3
Autor:
Iris P L Wong, Frank Driessler, Ee Cheng Khor, Yan-Chuan Shi, Birgit Hörmer, Amy D Nguyen, Ronaldo F Enriquez, John A Eisman, Amanda Sainsbury, Herbert Herzog, Paul A Baldock
Publikováno v:
PLoS ONE, Vol 7, Iss 7, p e40038 (2012)
BACKGROUND & AIMS: Gastrointestinal peptides are increasingly being linked to processes controlling the maintenance of bone mass. Peptide YY (PYY), a gut-derived satiety peptide of the neuropeptide Y family, is upregulated in some states that also di
Externí odkaz:
https://doaj.org/article/9b5a975859f44dad89830eefd9b9e082
Autor:
Amy D Nguyen, Natalie F Mitchell, Shu Lin, Laurence Macia, Ernie Yulyaningsih, Paul A Baldock, Ronaldo F Enriquez, Lei Zhang, Yan-Chuan Shi, Serge Zolotukhin, Herbert Herzog, Amanda Sainsbury
Publikováno v:
PLoS ONE, Vol 7, Iss 6, p e40191 (2012)
Neuropeptide Y (NPY) acting in the hypothalamus is one of the most powerful orexigenic agents known. Of the five known Y receptors, hypothalamic Y1 and Y5 have been most strongly implicated in mediating hyperphagic effects. However, knockout of indiv
Externí odkaz:
https://doaj.org/article/f2bbbf01b880484c8314e8794115371b
Autor:
Yan-Chuan Shi, Shu Lin, Iris P L Wong, Paul A Baldock, Aygul Aljanova, Ronaldo F Enriquez, Lesley Castillo, Natalie F Mitchell, Ji-Ming Ye, Lei Zhang, Laurence Macia, Ernie Yulyaningsih, Amy D Nguyen, Sabrina J Riepler, Herbert Herzog, Amanda Sainsbury
Publikováno v:
PLoS ONE, Vol 5, Iss 6, p e11361 (2010)
BACKGROUND: Y2 receptor signalling is known to be important in neuropeptide Y (NPY)-mediated effects on energy homeostasis and bone physiology. Y2 receptors are located post-synaptically as well as acting as auto receptors on NPY-expressing neurons,
Externí odkaz:
https://doaj.org/article/5a19b312bbf446788da289e4c0421dff
Publikováno v:
Molecular Metabolism, Vol 76, Iss , Pp 101790- (2023)
Objective: One of leptin's main targets in the hypothalamus are neuropeptide Y (NPY) neurons, with selective deletion of leptin receptors (Lepr) specifically in Npy neurons resulting in major alterations of energy partitioning between fat and bone ma
Externí odkaz:
https://doaj.org/article/8285223c4de5485298beef3c22249ded
Publikováno v:
International Journal of Obesity. 46:1749-1758
Background/Objective Female mice are often excluded from diet-induced obesity studies as they are more resistant to the obesifying effects of a high-fat diet (HFD). However, the underlying mechanisms behind this sex disparity may actually have import
Autor:
Chi Kin Ip, Natalie K.Y. Wee, Ronaldo F. Enriquez, Paul A. Baldock, Nicola J. Lee, Herbert Herzog, Yue Qi, Ireni Clarke
Publikováno v:
International Journal of Obesity. 44:2149-2164
Maintaining energy balance is important to ensure a healthy organism. However, energy partitioning, coordinating the distribution of sufficient energy to different organs and tissues is equally important, but the control of this process is largely un
Autor:
Ronaldo F. Enriquez, Chi Kin Ip, Luoning Gou, Paul Timpson, Zefeng Xia, Tianshu Zeng, Max Nobis, Qiao-Ping Wang, William E. Hughes, Kailun Lee, Jackie Lau, Hanyu Gao, Qi Wu, Chenxu Yan, Herbert Herzog, D. Ross Laybutt, Mohammed Bensellam, Lei Zhang, Yan-Chuan Shi, Jody J. Haigh, Zhongmin Gao, Kim Loh
Publikováno v:
Nature communications, Vol. 12, no.1, p. 2622 [1-20] (2021)
Nature Communications, Vol 12, Iss 1, Pp 1-20 (2021)
Nature Communications, Vol 12, Iss 1, Pp 1-20 (2021)
Obesity is caused by an imbalance between food intake and energy expenditure (EE). Here we identify a conserved pathway that links signalling through peripheral Y1 receptors (Y1R) to the control of EE. Selective antagonism of peripheral Y1R, via the