Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Ronald de Hoogt"'
Autor:
An Verheyen, Annick Diels, Joke Reumers, Kirsten Van Hoorde, Ilse Van den Wyngaert, Constantin van Outryve d’Ydewalle, An De Bondt, Jacobine Kuijlaars, Louis De Muynck, Ronald De Hoogt, Alexis Bretteville, Steffen Jaensch, Arjan Buist, Alfredo Cabrera-Socorro, Selina Wray, Andreas Ebneth, Peter Roevens, Ines Royaux, Pieter J. Peeters
Publikováno v:
Stem Cell Reports, Vol 11, Iss 2, Pp 363-379 (2018)
Summary: Tauopathies such as frontotemporal dementia (FTD) remain incurable to date, partially due to the lack of translational in vitro disease models. The MAPT gene, encoding the microtubule-associated protein tau, has been shown to play an importa
Externí odkaz:
https://doaj.org/article/301136220c5f4b20bc2ad49e591d873f
Autor:
Maarten Ooms, Sofie Celen, Ronald De Hoogt, Ilse Lenaerts, Johnny Liebregts, Greet Vanhoof, Xavier Langlois, Andrey Postnov, Michel Koole, Alfons Verbruggen, Koen Van Laere, Guy Bormans
Publikováno v:
EJNMMI Radiopharmacy and Chemistry, Vol 1, Iss 1, Pp 1-17 (2016)
Abstract Background Phosphodiesterase 10A (PDE10A) is an important regulator of nigrostriatal dopamine (DA) neurotransmission. However, little is known on the effect of alterations in DA neurotransmission on PDE10A availability. Here, we used [18F]JN
Externí odkaz:
https://doaj.org/article/d4dd4237d5784bcaae606d3049b031e4
Autor:
Michaël Barbier, Steffen Jaensch, Frans Cornelissen, Suzana Vidic, Kjersti Gjerde, Ronald de Hoogt, Ralph Graeser, Emmanuel Gustin, Yolanda T Chong, IMI PREDECT Consortium
Publikováno v:
PLoS ONE, Vol 11, Iss 6, p e0156942 (2016)
In oncology, two-dimensional in-vitro culture models are the standard test beds for the discovery and development of cancer treatments, but in the last decades, evidence emerged that such models have low predictive value for clinical efficacy. Theref
Externí odkaz:
https://doaj.org/article/d6adf23124fc40dca32e5c00a44812b3
Autor:
Regina Bökenkamp, Ronald van Brempt, Jacoba Cornelia van Munsteren, Ilse van den Wijngaert, Ronald de Hoogt, Livio Finos, Jelle Goeman, Adriana Cornelia Gittenberger-de Groot, Robert Eugen Poelmann, Nicolaas Andreas Blom, Marcus Cornelis DeRuiter
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e86892 (2014)
Closure of the ductus arteriosus (DA) is a crucial step in the transition from fetal to postnatal life. Patent DA is one of the most common cardiovascular anomalies in children with significant clinical consequences especially in premature infants. W
Externí odkaz:
https://doaj.org/article/e3847d600731414ba36e5d93e14bd9d9
Publikováno v:
BioTechniques, Vol 28, Iss 6, Pp 1112-1116 (2000)
Because Candida albicans is a diploid organism, two consecutive steps of gene disruption are required to generate a gene knock-out. The same marker (URA3) is often used for disruption of both copies of the gene. This is possible because, after the fi
Externí odkaz:
https://doaj.org/article/df712a7e72454101aeed26220852f709
Autor:
Gert De Hertogh, Bart Lemmens, Peter Verhasselt, Ronald de Hoogt, Xavier Sagaert, Marie Joossens, Gert Van Assche, Paul Rutgeerts, Severine Vermeire, Jeroen Aerssens
Publikováno v:
International Journal of Inflammation, Vol 2012 (2012)
The microbiota of the gastrointestinal tract is frequently mentioned as one of the key players in the etiopathogenesis of Crohn's disease (CD). Four hypotheses have been suggested: the single, still unknown bacterial pathogen, an abnormal overall com
Externí odkaz:
https://doaj.org/article/5f835aebd7d041de993f3ccae034e4ea
Autor:
Suzana, Vidic, Marta F, Estrada, Kjersti, Gjerde, Vítor E, Santo, Annika, Osswald, Michaël, Barbier, Yolanda T, Chong, Wolfgang, Sommergruber, Ronald, de Hoogt, Catarina, Brito, Ralph, Graeser
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1888
PREDECT, a European IMI consortium, has assumed the task to generate robust 2D and 3D culture platforms. Protocols established for 2D and 3D monoculture and stromal coculture models of increasing complexity (spheroid, stirred-tank bioreactor, Matrige
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c1ebea1f2c21d147bd3a7c356cbb4ad9
https://pubmed.ncbi.nlm.nih.gov/30519938
https://pubmed.ncbi.nlm.nih.gov/30519938
Autor:
Vítor E. Santo, Marta Estrada, Suzana Vidic, Michaël Barbier, Kjersti Gjerde, Yolanda T. Chong, Wolfgang Sommergruber, Ronald de Hoogt, Catarina Brito, Ralph Graeser, Annika Osswald
Publikováno v:
Methods in Molecular Biology ISBN: 9781493988907
PREDECT, a European IMI consortium, has assumed the task to generate robust 2D and 3D culture platforms. Protocols established for 2D and 3D monoculture and stromal coculture models of increasing complexity (spheroid, stirred-tank bioreactor, Matrige
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3a0617cec040cbfde6a90a4d98a3bfe1
https://doi.org/10.1007/978-1-4939-8891-4_1
https://doi.org/10.1007/978-1-4939-8891-4_1
Autor:
P. Roevens, Constantin d’Ydewalle, Andreas Ebneth, Jacobine Kuijlaars, Selina Wray, Annick Diels, Alexis Bretteville, Arjan Buist, An Verheyen, Joke Reumers, Alfredo Cabrera-Socorro, Ronald de Hoogt, Louis De Muynck, Ines Royaux, Kirsten Van Hoorde, An De Bondt, Ilse Van den Wyngaert, Pieter J. Peeters, Steffen Jaensch
Publikováno v:
Stem Cell Reports
Stem Cell Reports, Vol 11, Iss 2, Pp 363-379 (2018)
Stem Cell Reports, Vol 11, Iss 2, Pp 363-379 (2018)
Summary Tauopathies such as frontotemporal dementia (FTD) remain incurable to date, partially due to the lack of translational in vitro disease models. The MAPT gene, encoding the microtubule-associated protein tau, has been shown to play an importan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::289053eeca74e9ffdb9f09f03595c36a
https://pubmed.ncbi.nlm.nih.gov/31412287
https://pubmed.ncbi.nlm.nih.gov/31412287
Autor:
Emmy W. Verschuren, Vítor E. Santo, Meng Dong, Erwin R. Boghaert, Katja Närhi, Wolfgang Sommergruber, Kjersti Gjerde, Suzana Vidic, Annika Osswald, Hanneke J. A. A. van Zoggel, Sami Blom, Emma J. Davies, Ronald de Hoogt, Marta Estrada, Yolanda T. Chong, Ralph Graeser, John A. Hickman, Heiko van der Kuip, Wytske M. van Weerden, Catarina Brito, Michaël Barbier
Publikováno v:
Scientific Data
Scientific data, 4:170170. Nature Publishing Group
Scientific data, 4:170170. Nature Publishing Group
Two-dimensional (2D) culture of cancer cells in vitro does not recapitulate the three-dimensional (3D) architecture, heterogeneity and complexity of human tumors. More representative models are required that better reflect key aspects of tumor biolog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ba90130e39d47b546cf713b8335e873
https://hdl.handle.net/1765/103030
https://hdl.handle.net/1765/103030