Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Ronald Winston"'
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
By promoting the cytotoxic function of CD8+ T cells, immune checkpoint inhibitor therapy, e.g. programmed cell death protein-1 (PD-1), effectively inhibits tumor growth in renal cell carcinoma. Yet, as many as 87% of cancer patients do not respond to
Externí odkaz:
https://doaj.org/article/6bb0a240dc204ceeb8ef6deca7ee997a
Autor:
Cynthia L. Bristow, Ronald Winston
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
The abundant blood protein α1-proteinase inhibitor (α1PI, Αlpha-1, α1-antitrypsin, SerpinA1) is known to bind to the active site of granule-associated human leukocyte elastase (HLE-G). Less well known is that binding of α1PI to cell surface HLE
Externí odkaz:
https://doaj.org/article/6bea733d37fd4097bb421499fcd652f9
Autor:
Cynthia L. Bristow, Sara Ferrando-Martinez, Ezequiel Ruiz-Mateos, Manuel Leal, Ronald Winston
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 7 (2019)
Immune cells are, by default, migratory cells that traverse tissue for the purpose of carrying out recognition and recruitment in pathologic inflammation and infection. Members of the LDL receptor family (LDL-RFMs) interact with human leukocyte elast
Externí odkaz:
https://doaj.org/article/c7861f8cef5a46a3873a156dbe981cc6
Publikováno v:
PLoS ONE, Vol 7, Iss 2, p e31383 (2012)
BackgroundThe regulation of adult stem cell migration through human hematopoietic tissue involves the chemokine CXCL12 (SDF-1) and its receptor CXCR4 (CD184). In addition, human leukocyte elastase (HLE) plays a key role. When HLE is located on the ce
Externí odkaz:
https://doaj.org/article/e24040399ee846b39af1961718c3c8fc
Autor:
Cynthia L. Bristow, Ronald Winston
Publikováno v:
Trends in immunology. 42(3)
Autor:
Ronald Winston, William Stadiem
This authoritative and intimate biography, written by his only living son, Ronald Winston, marries the Gilded Age glamour and romance of Edith Wharton with the ruthless family dynamics of HBO's hit series, Succession. Few American success stories riv
Publikováno v:
The Journal of Immunology. 206:67.04-67.04
By promoting the cytotoxic function of CD8+ T cells, immune checkpoint inhibitor therapy, e.g. programmed cell death protein-1 (PD-1), effectively inhibits tumor growth in renal cell carcinoma. Yet, as many as 87% of cancer patients do not respond to
Publikováno v:
Experimental Hematology. 29:1004-1009
Objective IgM antibodies reactive with each of two specifically defined sequences of HIV Tat protein have been identified in sera from both HIV + and normal (HIV − ) humans. This study was designed to confirm that those antibodies are innate immune
Publikováno v:
Human Immunology. 60:631-639
We have previously reported, and confirm here, that the human innate system of natural antibodies includes two, each of which is reactive, presumably by happenstance, with a specific sequence of HIV Tat protein. Comparison of cohorts of HIV + and nor
Autor:
Cynthia L, Bristow, Rozbeh, Modarresi, Mariya A, Babayeva, Michelle, LaBrunda, Roya, Mukhtarzad, Maylis, Trucy, Aaron, Franklin, Rudy E R, Reeves, Allegra, Long, Michael P, Mullen, Jose, Cortes, Ronald, Winston
Publikováno v:
Discovery medicine. 16(89)
Dietary lipids are transported via lymph to the liver and transformed to lipoproteins which bind to members of the low density lipoprotein receptor family (LDL-RFMs). Certain LDL-RFMs, e.g., very low density lipoprotein receptor (VLDLR), are also bou