Zobrazeno 1 - 10
of 153
pro vyhledávání: '"Ronald W Millard"'
Autor:
Bin Yu, Yueting Yang, Huan Liu, Min Gong, Ronald W Millard, Yi-Gang Wang, Muhammad Ashraf, Meifeng Xu
Publikováno v:
PLoS ONE, Vol 11, Iss 3, p e0151542 (2016)
BACKGROUND:Clusterin (Clu) is a stress-responding protein with multiple biological functions. Our preliminary microarray studies show that clusterin was prominently upregulated in mesenchymal stem cells (MSCs) overexpressing GATA-4 (MSCGATA-4). We hy
Externí odkaz:
https://doaj.org/article/a2257d7bbed046e7bcc4d872ad2ebeac
Autor:
Dehua Chang, Zhili Wen, Yuhua Wang, Wenfeng Cai, Mashhood Wani, Christian Paul, Teruo Okano, Ronald W Millard, Yigang Wang
Publikováno v:
PLoS ONE, Vol 9, Iss 10, p e107296 (2014)
Implantation of cell-sheets into damaged regions of the heart after myocardial infarction (MI) has been shown to improve heart function. However, the tissue morphology following application of induced pluripotent stem cell (iPSC)-derived cardiomyocyt
Externí odkaz:
https://doaj.org/article/e14ca96dfdc64ae2b89de3774014fd9c
Autor:
Zhili Wen, Wei Huang, Yuliang Feng, Wenfeng Cai, Yuhua Wang, Xiaohong Wang, Jialiang Liang, Mashhood Wani, Jing Chen, Pin Zhu, Ji-Mei Chen, Ronald W Millard, Guo-Chang Fan, Yigang Wang
Publikováno v:
PLoS ONE, Vol 9, Iss 9, p e104666 (2014)
MicroRNAs have been appreciated in various cellular functions, including the regulation of angiogenesis. Mesenchymal-stem-cells (MSCs) transplanted to the MI heart improve cardiac function through paracrine-mediated angiogenesis. However, whether mic
Externí odkaz:
https://doaj.org/article/a3d89ad266b7416f95793ed89912e3ef
Autor:
Linlin Wang, Zeeshan Pasha, Shuyun Wang, Ning Li, Yuliang Feng, Gang Lu, Ronald W Millard, Muhammad Ashraf
Publikováno v:
PLoS ONE, Vol 8, Iss 3, p e60087 (2013)
We hypothesized that overexpression of cGMP-dependent protein kinase type 1α (PKG1α) could mimic the effect of tadalafil on the survival of bone marrow derived mesenchymal stem cells (MSCs) contributing to regeneration of the ischemic heart.MSCs fr
Externí odkaz:
https://doaj.org/article/1b88e7a6aa65428fbf91f98e5115c2e6
Autor:
Wei Huang, Bo Dai, Zhili Wen, Ronald W Millard, Xi-Yong Yu, Kristin Luther, Meifeng Xu, Ting C Zhao, Huang-Tian Yang, Zhihua Qi, Kathleen Lasance, Muhammad Ashraf, Yigang Wang
Publikováno v:
PLoS ONE, Vol 8, Iss 8, p e70023 (2013)
OBJECTIVE:The purpose of this study was to assess the effect of collagen composition on engraftment of progenitor cells within infarcted myocardium. BACKGROUND:We previously reported that intramyocardial penetration of stem/progenitor cells in epicar
Externí odkaz:
https://doaj.org/article/a51dc0b082b14502802745f7084e9ec4
Autor:
Bin Yu, Min Gong, Yigang Wang, Ronald W Millard, Zeeshan Pasha, Yueting Yang, Muhammad Ashraf, Meifeng Xu
Publikováno v:
PLoS ONE, Vol 8, Iss 8, p e73304 (2013)
microRNAs (miRs), a novel class of small non-coding RNAs, are involved in cell proliferation, differentiation, development, and death. In this study, we found that miR-221 translocation by microvesicles (MVs) plays an important role in cardioprotecti
Externí odkaz:
https://doaj.org/article/155fbb3ccfee4af0999974f77d53b6aa
Autor:
Jialiang Liang, Wei Huang, Xiyong Yu, Atif Ashraf, Kishore K Wary, Meifeng Xu, Ronald W Millard, Muhammad Ashraf, Yigang Wang
Publikováno v:
PLoS ONE, Vol 7, Iss 9, p e46158 (2012)
BACKGROUND:Our previous studies indicated that MSC(CXCR4) improved cardiac function after myocardial infarction (MI). This study was aimed to investigate the specific role of MSC(CXCR4) in neovascularization of infarcted myocardium using a suicide ge
Externí odkaz:
https://doaj.org/article/1c704d5cb7994183a76a327c1c342e42
Autor:
Min Liu, Yigang Wang, Meifeng Xu, Christian Paul, De Sheng Xiao, Muhammad Ashraf, Ronald W. Millard, Bin Yu, Min Gong, Jingcai Wang
Publikováno v:
Oncotarget
Mesenchymal stem cells (MSCs) have been found to benefit patients with a variety of ischemic diseases via promoting angiogenesis. It is also well established that exosomes secreted from MSCs deliver bioactive molecules, including microRNAs (miRs) to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::318022e23d2285870f9635aa78ac25a6
http://europepmc.org/articles/PMC5542178
http://europepmc.org/articles/PMC5542178
Autor:
Motoi Okada, Christian Paul, Hideyuki Kondo, Lei Wang, Ronald W. Millard, Ha Won Kim, Yigang Wang
Publikováno v:
Aging Cell
Summary The low reprogramming efficiency in cells from elderly patients is a challenge that must be overcome. Recently, it has been reported that senescence‐associated microRNA (miR)‐195 targets Sirtuin 1 (SIRT1) to advance cellular senescence. T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55bf41d63ccfb46a0f1e9b120232418f
http://europepmc.org/articles/PMC4717278
http://europepmc.org/articles/PMC4717278
Autor:
Xiao-Lan Zhu, Yigang Wang, Lin Jiang, Christian Paul, Ronald W. Millard, Peter J. Stambrook, Wenfeng Cai, Jianguo G. Gu, Jialiang Liang, Yuliang Feng, Wei Huang, Ping Zhu, Zhanfeng Jia
Publikováno v:
Exp Cell Res
Although resident cardiac stem cells have been reported, regeneration of functional cardiomyocytes (CMs) remains a challenge. The present study identifies an alternative progenitor source for CM regeneration without the need for genetic manipulation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b781a69ca5f2bfa60cab650392eed092
https://pubmed.ncbi.nlm.nih.gov/29842877
https://pubmed.ncbi.nlm.nih.gov/29842877