Zobrazeno 1 - 10
of 134
pro vyhledávání: '"Ronald W Holz"'
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
The adrenal medulla plays a critical role in mammalian homeostasis and the stress response. It is populated by clustered chromaffin cells that secrete epinephrine or norepinephrine along with peptides into the bloodstream affecting distant target org
Externí odkaz:
https://doaj.org/article/10a96504b0ca48bc9538d8064af23505
Autor:
Ronald W Holz, Daniel Axelrod
Publikováno v:
Exocytosis: From Molecules to Cells ISBN: 9780750337717
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c8b1d1571851b58bc58f8c611a641662
https://doi.org/10.1088/978-0-7503-3771-7ch4
https://doi.org/10.1088/978-0-7503-3771-7ch4
Autor:
Arun Anantharam, Ronald W Holz
Publikováno v:
Exocytosis: From Molecules to Cells ISBN: 9780750337717
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0d86fc9a626e8fd2026d52d8d1c1fabc
https://doi.org/10.1088/978-0-7503-3771-7ch12
https://doi.org/10.1088/978-0-7503-3771-7ch12
Publikováno v:
Molecular biology of the cell. 33(6)
Granule-plasma membrane docking and fusion can only occur when proteins that enable these reactions are present at the granule-plasma membrane contact. Thus, the mobility of granule membrane proteins may influence docking, and membrane fusion. We mea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f66d17407f89cb9c3b63561c79d6d291
https://pubmed.ncbi.nlm.nih.gov/34851717
https://pubmed.ncbi.nlm.nih.gov/34851717
The adrenal medulla has long been recognized as playing a critical role in mammalian homeostasis and the stress response. The adrenal medulla is populated by clustered chromaffin cells that secrete epinephrine or norepinephrine along with other pepti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::687f828e231876e901b2fae53f317bcc
https://doi.org/10.1101/2021.04.13.439677
https://doi.org/10.1101/2021.04.13.439677
Although many of the proteins of secretory granules have been identified, little is known about their molecular organization and diffusion characteristics. Granule-plasma membrane fusion can only occur when proteins that enable fusion are present at
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7577bc959d8cd6960aae899aad28ec6e
https://doi.org/10.1101/2021.02.20.432015
https://doi.org/10.1101/2021.02.20.432015
Autor:
Mary A. Bittner, Ronald W. Holz
Publikováno v:
The Journal of General Physiology
The domain in SNAP25 that links its two SNARE motifs plays important roles in fusion pore formation, secretion kinetics, and the formation of a dynamic plasma membrane SNAP25/syntaxin “acceptor” complex for the v-SNARE synaptobrevin.
Central
Central
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbda99f1eb90b275b28732081b6c1e5f
Publikováno v:
The Journal of General Physiology
Secretory cells package their protein cargo into granules, which must fuse with the plasma membrane for these proteins to be released. Such exocytosis requires not only fusion of the granule membrane with the plasma membrane but also expansion of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe41b9be57a7ac0037844c3e8b40247f
https://doi.org/10.1085/jgp.201812186
https://doi.org/10.1085/jgp.201812186
Publikováno v:
Microsc Microanal
The refractive index in the interior of single cells affects the evanescent field depth in quantitative studies using total internal reflection (TIR) fluorescence, but often that index is not well known. We here present method to measure and spatiall
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::021e9b1a1ff4024e3be2d5b328369fc1
https://doi.org/10.1017/s1431927617012570
https://doi.org/10.1017/s1431927617012570
Autor:
Joshua Zimmerberg, Ronald W. Holz
Publikováno v:
Biophys J
Fusion of secretory granules and synaptic vesicles with the plasma membrane is driven by SNARE protein interactions. Intensive investigations in vitro, which include x-ray crystallography, cryoelectron microscopy, and NMR analyses by numerous groups,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03c9968724fb0aa3dee17bc789710b54
https://pubmed.ncbi.nlm.nih.gov/31378313
https://pubmed.ncbi.nlm.nih.gov/31378313