Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Ronald Tuccelli"'
Autor:
David K. Gemmell, Aaron Mack, Sabrina Wegmann, David Han, Ronald Tuccelli, Matthew Johnson, Corinne Miller
Publikováno v:
Engineering in Life Sciences, Vol 21, Iss 7, Pp 502-513 (2021)
Abstract There is a growing need to provide effective adventitious agent mitigation for high risk upstream cell culture raw materials used for the production of biologics. It is also highly important in the growing fields of cell and gene therapies.
Externí odkaz:
https://doaj.org/article/5a9cdd4b3efc4953a56a3c92c6d768d6
Autor:
Melissa Holstein, Ronald Tuccelli, John Caulmare, Patricia Greenhalgh, Kristen Cotoni, Lori Mullin, Christopher Gillespie
Publikováno v:
Biotechnology Journal
Viral inactivation plays a critical role in assuring the safety of monoclonal antibody (mAb) therapeutics. Traditional viral inactivation involves large holding tanks in which product is maintained at a target low pH for a defined hold time, typicall