Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Ronald S. Aronson"'
Autor:
Daniel E. Singer, Steven J. Atlas, Alan S. Go, Renato D. Lopes, Steven A. Lubitz, David D. McManus, James H. Revkin, Donna Mills, Lori A. Crosson, Judith C. Lenane, Ronald S. Aronson
Publikováno v:
American heart journal. 249
Screening for atrial fibrillation (AF) is attractive because AF independently raises the risk of ischemic stroke, this risk is largely reversible by long-term oral anticoagulant therapy (OAC), and many patients with AF remain undiagnosed and untreate
Autor:
Daniel E. Singer, Steven Atlas, Alan S. Go, Renato D. Lopes, Steven Lubitz, David McManus, James H. Revkin, Donna Mills, Lori Crosson, Judith C. Lenane, Ronald S. Aronson
Publikováno v:
Journal of the American College of Cardiology. 79:28
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 267:H1419-H1428
We investigated possible ionic mechanisms that cause early afterdepolarizations (EADs) following the injection of constant inward current in guinea pig ventricular myocytes by several interventions that affect failure of action potential repolarizati
Publikováno v:
Journal of Cardiovascular Electrophysiology. 5:323-334
Ionic Mechanism of EADs. Introduction: Early afterdepolarizations (EADs) can give rise to triggered activity and thereby produce cardiac arrhythmias. We used the whole-cell patch clamp technique to examine the relationship between L-type Ca2+ channel
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 261:H514-H530
We investigated the basis for impaired left ventricular function of hearts in which hypertrophy was produced by gradual pressure overload. We measured myoplasmic free calcium concentration ([Ca2+]i) with fura-2 and sarcomere shortening in single myoc
Autor:
Ronald S. Aronson
Publikováno v:
Journal of Cardiovascular Electrophysiology. 2:249-261
Mechanisms of Arrhythmias in Ventricular Hypertrophy. Cardiac hypertrophy is an adaptative process by which the heart accommodates to abnormal pressure and volume overloads. However, hypertrophy of the left ventricle is associated with a high inciden
Autor:
Ronald S. Aronson, Paul F. Cranefield
Publikováno v:
Cardiovascular Drugs and Therapy. 5:531-537
It is suggested that torsades de pointes may be only one of a group of arrhythmias that are characterized by being pause induced or bradycardia induced. A distinction is made between the cause of the "twisting of the points" and the cause of the acti
Publikováno v:
Journal of Cardiovascular Pharmacology. 16:267-275
Triggered activity induced by delayed afterdepolarizations has been suggested as a cellular mechanism for some arrhythmias. The development of triggered activity should be favored by conditions that increase myoplasmic Ca2+ and increase membrane resi
Autor:
Peter K. Keller, Ronald S. Aronson
Publikováno v:
Progress in Cardiovascular Diseases. 32:433-448
T HE RELATIONSHIP between electrolyte deficiencies and the development and prevention of cardiac arrhythmias has been a subject of continued interest in the medical literature. Studies have suggested a correlation between certain electrolyte deficien
Publikováno v:
Journal of Molecular and Cellular Cardiology. 22:619-628
This study investigates the role of reducing potassium conductance (gK) in generating delayed afterdepolarizations and triggered activity in small preparations of ventricular muscle from guinea-pig hearts. We used agents believed to reduce gK (low or