Zobrazeno 1 - 10
of 439
pro vyhledávání: '"Ronald S Duman"'
Autor:
Stephanie Simard, Pragya Shail, Jessica MacGregor, Maha El Sayed, Ronald S Duman, Flora M Vaccarino, Natalina Salmaso
Publikováno v:
PLoS ONE, Vol 13, Iss 10, p e0204980 (2018)
Previous research has shown that fibroblast growth factor 2 protein (FGF2) can act as an anxiolytic and anti-depressive agent in rodents. Levels of hippocampal FGF2 and FGF2 receptors are decreased in post-mortem brains of individuals with mood disor
Externí odkaz:
https://doaj.org/article/4b6680cfd7964d30aa57fdbf7c014100
Autor:
Pawel Licznerski, Vanja Duric, Mounira Banasr, Kambiz N Alavian, Kristie T Ota, Hyo Jung Kang, Elizabeth A Jonas, Robert Ursano, John H Krystal, Ronald S Duman, Traumatic Stress Brain Study Group
Publikováno v:
PLoS Biology, Vol 13, Iss 10, p e1002282 (2015)
Exposure to extreme stress can trigger the development of major depressive disorder (MDD) as well as post-traumatic stress disorder (PTSD). The molecular mechanisms underlying the structural and functional alterations within corticolimbic brain regio
Externí odkaz:
https://doaj.org/article/80f1f1c285684de08991174b81c6301c
Autor:
Miyeon Choi, Sung Eun Wang, Seung Yeon Ko, Hyo Jung Kang, Seung Yeun Chae, Seung Hoon Lee, Yong-Seok Kim, Ronald S Duman, Hyeon Son
Publikováno v:
PLoS ONE, Vol 9, Iss 10, p e109253 (2014)
Functional consequences to which vertebrate GATA transcription factors contribute in the adult brain remain largely an open question. The present study examines how human GATA-1 and GATA-2 (hGATA-1 and hGATA-2) are linked to neuronal differentiation
Externí odkaz:
https://doaj.org/article/9dfb204f7480436c8cadc967f4b47e79
Autor:
Melissa S Monsey, Lara M Boyle, Melinda L Zhang, Caroline P Nguyen, Hope G Kronman, Kristie T Ota, Ronald S Duman, Jane R Taylor, Glenn E Schafe
Publikováno v:
PLoS ONE, Vol 9, Iss 3, p e91530 (2014)
Chronic exposure to stress has been widely implicated in the development of anxiety disorders, yet relatively little is known about the long-term effects of chronic stress on amygdala-dependent memory formation. Here, we examined the effects of a his
Externí odkaz:
https://doaj.org/article/e3a34163a26d450593d25b094017dbf9
Publikováno v:
Neuropsychopharmacology Reports, Vol 44, Iss 1, Pp 246-249 (2024)
Abstract Vascular endothelial growth factor (VEGF) signaling is known to be involved in the antidepressant‐like effects of conventional antidepressants, such as desipramine (DMI), a tricyclic antidepressant, and fluoxetine (FLX), a selective seroto
Externí odkaz:
https://doaj.org/article/cc74544c92bd4e53b9bdb78a800dac3e
Publikováno v:
Translational Psychiatry, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Recent studies have implicated the endogenous opioid system in the antidepressant actions of ketamine, but the underlying mechanisms remain unclear. We used a combination of pharmacological, behavioral, and molecular approaches in rats to te
Externí odkaz:
https://doaj.org/article/afafdeb3c86749338da17daee958b2fe
Autor:
Minal Jaggar, Shreya Ghosh, Balaganesh Janakiraman, Ashmita Chatterjee, Megha Maheshwari, Vani Dewan, Brendan Hare, Sukrita Deb, Dwight Figueiredo, Ronald S Duman, Vidita A Vaidya
Publikováno v:
International Journal of Neuropsychopharmacology. 26:294-306
Background Electroconvulsive seizure therapy is often used in both treatment-resistant and geriatric depression. However, preclinical studies identifying targets of chronic electroconvulsive seizure (ECS) are predominantly focused on animal models in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::09849802867bc6055a08a6bbe73cf536
https://doi.org/10.1093/ijnp/pyad008
https://doi.org/10.1093/ijnp/pyad008
Autor:
Polymnia Georgiou, Panos Zanos, Ta-Chung M. Mou, Xiaoxian An, Danielle M. Gerhard, Dilyan I. Dryanovski, Liam E. Potter, Jaclyn N. Highland, Carleigh E. Jenne, Brent W. Stewart, Katherine J. Pultorak, Peixiong Yuan, Chris F. Powels, Jacqueline Lovett, Edna F. R. Pereira, Sarah M. Clark, Leonardo H. Tonelli, Ruin Moaddel, Carlos A. Zarate, Ronald S. Duman, Scott M. Thompson, Todd D. Gould
Publikováno v:
Nat Neurosci
We show that the sex of human experimenters affects mouse behaviors and responses following administration of the rapid-acting antidepressant ketamine and its bioactive metabolite (2R,6R)-hydroxynorketamine. Mice showed aversion to the scent of male
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2785218ca391a1003e91994de1564c3
https://doi.org/10.1038/s41593-022-01146-x
https://doi.org/10.1038/s41593-022-01146-x
Publikováno v:
Neuropsychopharmacology.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::22c5611491c6156f9fa83336f0d65d32
https://doi.org/10.1038/s41386-023-01583-7
https://doi.org/10.1038/s41386-023-01583-7
Autor:
Boyoung Lee, Santosh Pothula, Min Wu, Hyeyeon Kang, Matthew J. Girgenti, Marina R. Picciotto, Ralph J. DiLeone, Jane R. Taylor, Ronald S. Duman
Publikováno v:
Molecular Psychiatry. 27:2580-2589
N-methyl-D-aspartate receptor (NMDAR) modulators have recently received increased attention as potential therapeutics for posttraumatic stress disorder (PTSD). Here, we tested a novel NMDAR-positive modulator, NYX-783, in the following two rodent mod
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2c09b18a4cd0d77115ce31d25d1559c3
https://doi.org/10.1038/s41380-022-01498-7
https://doi.org/10.1038/s41380-022-01498-7