Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Ronald R. Marchelletta"'
Autor:
Young Su Park, Sang Bum Kang, Ronald R. Marchelletta, Harrison M. Penrose, Roos Ruiter-Visser, Barbara Jung, Michael J. Docherty, Brigid S. Boland, William J. Sandborn, Declan F. McCole
Publikováno v:
Pharmaceutics, Vol 15, Iss 3, p 811 (2023)
The prostone analog, lubiprostone, is approved to manage constipation-predominant irritable bowel syndrome. Lubiprostone also protects intestinal mucosal barrier function in animal models of colitis. The aim of this study was to determine if lubipros
Externí odkaz:
https://doaj.org/article/5f068f2b880b4b1ab6c054eb34c860c1
Autor:
Barun Das, Kevin Okamoto, John Rabalais, Ronald R. Marchelletta, Kim E. Barrett, Soumita Das, Maho Niwa, Mamata Sivagnanam
Publikováno v:
Cells, Vol 9, Iss 4, p 946 (2020)
Congenital tufting enteropathy (CTE) is a rare chronic diarrheal disease of infancy caused by mutations in epithelial cell adhesion molecule (EpCAM). Previously, a murine CTE model showed mis-localization of EpCAM away from the basolateral cell surfa
Externí odkaz:
https://doaj.org/article/3dbb270ff7f54b17916142b6701171e3
Autor:
Michel L. Tremblay, Ronald R. Marchelletta, Kim E. Barrett, Bechara Kachar, Elaine M. Hanson, Rocio Alvarez, Evan S. Krystofiak, Moorthy Krishnan, Marianne R. Spalinger, Stephen J Myers, Declan F. McCole, Lars Eckmann, Young Su Park, Lucas Bernts, Anica Sayoc-Becerra, Vinicius Canale, Dermot P.B. McGovern, Taylaur W. Placone, Ali Shawki, Christopher R. Weber
Publikováno v:
Journal of Clinical Investigation. 131
Genome-wide association studies revealed that loss-of-function mutations in protein tyrosine phosphatase non-receptor type 2 (PTPN2) increase the risk of developing chronic immune diseases, such as inflammatory bowel disease (IBD) and celiac disease.
Autor:
McGeough, Ronald R. Marchelletta, Philip Kozan, Nassim Durali, Kevin Okamoto, Barun Das, Tsan-Wen Lu, Jihwan Lee, Mamata Sivagnanam, Kim E. Barrett, John Rabalais
BackgroundFoeniculum vulgare,F. vulgare, commonly known as fennel, is believed to be one of the world’s oldest medicinal herbs and has been exploited by people for centuries as a nutritional aid for digestive disorders. In many southeast Asian coun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8583eaf6be72b40677e27a393f886ddf
https://doi.org/10.1101/2021.07.01.450766
https://doi.org/10.1101/2021.07.01.450766
Autor:
Anica Sayoc-Becerra, Cheryl A. Stork, Declan F. McCole, Rocio Alvarez, Ronald R. Marchelletta, G. Kim Prisk
Publikováno v:
Scientific Reports
Scientific reports, vol 9, iss 1
Scientific Reports, Vol 9, Iss 1, Pp 1-15 (2019)
Scientific reports, vol 9, iss 1
Scientific Reports, Vol 9, Iss 1, Pp 1-15 (2019)
Intestinal epithelial cell (IEC) junctions constitute a robust barrier to invasion by viruses, bacteria and exposure to ingested agents. Previous studies showed that microgravity compromises the human immune system and increases enteropathogen virule
Autor:
Mamata Sivagnanam, Barun Das, Kevin Okamoto, John Rabalais, Kim E. Barrett, Nassim Durali, Philip Kozan, Ronald R. Marchelletta, Soumita Das, Maria Go, Matthew D. McGeough
Publikováno v:
Am J Physiol Gastrointest Liver Physiol
Congenital tufting enteropathy (CTE) is an autosomal recessive disease characterized by severe intestinal failure in infancy and mutations in the epithelial cell adhesion molecule ( EPCAM) gene. Previous studies of CTE in mice expressing mutant EpCAM
Autor:
Maho Niwa, Barun Das, Kevin Okamoto, John Rabalais, Kim E. Barrett, Mamata Sivagnanam, Soumita Das, Ronald R. Marchelletta
Publikováno v:
Cells, vol 9, iss 4
Cells
Volume 9
Issue 4
Cells, Vol 9, Iss 946, p 946 (2020)
Cells
Volume 9
Issue 4
Cells, Vol 9, Iss 946, p 946 (2020)
Congenital tufting enteropathy (CTE) is a rare chronic diarrheal disease of infancy caused by mutations in epithelial cell adhesion molecule (EpCAM). Previously, a murine CTE model showed mis-localization of EpCAM away from the basolateral cell surfa
Autor:
Lingquan Deng, Frederico Alisson-Silva, Janet Z. Liu, Ajit Varki, Mélanie G. Gareau, Kim E. Barrett, Nissi Varki, Sandra Diaz, Ronald R. Marchelletta, Xi Chen, Victor Nizet
Publikováno v:
PLoS pathogens, vol 14, iss 6
PLoS Pathogens
PLoS Pathogens, Vol 14, Iss 6, p e1007133 (2018)
PLoS Pathogens
PLoS Pathogens, Vol 14, Iss 6, p e1007133 (2018)
While infectious agents have typical host preferences, the noninvasive enteric bacterium Vibrio cholerae is remarkable for its ability to survive in many environments, yet cause diarrheal disease (cholera) only in humans. One key V. cholerae virulenc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0e066df971ecbd3cd537046cfcd5c33
https://escholarship.org/uc/item/9z44t3pn
https://escholarship.org/uc/item/9z44t3pn
Autor:
Ronald R. Marchelletta, Joshua Fierer, Sharon Okamoto, Mélanie G. Gareau, Kim E. Barrett, Donald G. Guiney
Publikováno v:
The Journal of infectious diseases, vol 212, iss 1
Background. Gastroenteritis is the most common manifestation of nontyphoidal Salmonella enterica infections, but little is known about the pathogenesis of diarrhea in this infection Methods. To determine whether polymorphonuclear neutrophils (PMNs) a
Autor:
Ronald R. Marchelletta, Nilay N. Shah, Declan F. McCole, Harrison M. Penrose, Moorthy Krishnan
Background VSL#3 is a probiotic compound that has been used in the treatment of inflammatory bowel disease. T-cell protein tyrosine phosphatase (TCPTP) is the protein product of the inflammatory bowel disease candidate gene, PTPN2, and we have previo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b0f876e09d1bf9843daf4280c7791c3
https://europepmc.org/articles/PMC5779620/
https://europepmc.org/articles/PMC5779620/