Zobrazeno 1 - 10
of 340
pro vyhledávání: '"Ronald R De Krijger"'
Autor:
Prakriti Roy, Sophie E van Peer, Martin M de Witte, Godelieve A M Tytgat, Henrike E Karim-Kos, Martine van Grotel, Cees P van de Ven, Annelies M C Mavinkurve-Groothuis, Johannes H M Merks, Roland P Kuiper, Janna A Hol, Geert O R Janssens, Ronald R de Krijger, Marjolijn C J Jongmans, Jarno Drost, Alida F W van der Steeg, Annemieke S Littooij, Marc H W A Wijnen, Harm van Tinteren, Marry M van den Heuvel-Eibrink
Publikováno v:
PLoS ONE, Vol 17, Iss 1, p e0261729 (2022)
Around 6% of all childhood malignancies represent renal tumors, of which a majority includes Wilms tumor (WT). Although survival rates have improved over the last decades, specific patients are still at risk for adverse outcome. In the Netherlands, s
Externí odkaz:
https://doaj.org/article/cbd09bdea6be4771a698026673ed7536
Autor:
Erwin Brosens, Janine F Felix, Anne Boerema-de Munck, Elisabeth M de Jong, Elisabeth M Lodder, Sigrid Swagemakers, Marjon Buscop-van Kempen, Ronald R de Krijger, Rene M H Wijnen, Wilfred F J van IJcken, Peter van der Spek, Annelies de Klein, Dick Tibboel, Robbert J Rottier
Publikováno v:
PLoS ONE, Vol 15, Iss 11, p e0242167 (2020)
Esophageal atresia (EA) and tracheoesophageal fistula (TEF) are relatively frequently occurring foregut malformations. EA/TEF is thought to have a strong genetic component. Not much is known regarding the biological processes disturbed or which cell
Externí odkaz:
https://doaj.org/article/86775dfab8754da684eea651fe11660b
Autor:
Thomas A. Kluiver, Yuyan Lu, Stephanie A. Schubert, Lianne J. Kraaier, Femke Ringnalda, Philip Lijnzaad, Jeff DeMartino, Wouter L. Megchelenbrink, Vicky Amo-Addae, Selma Eising, Flavia W. de Faria, Daniel Münter, Marc van de Wetering, Kornelius Kerl, Evelien Duiker, Marius C. van den Heuvel, Vincent E. de Meijer, Ruben H. de Kleine, Jan J. Molenaar, Thanasis Margaritis, Hendrik G. Stunnenberg, Ronald R. de Krijger, József Zsiros, Hans Clevers, Weng Chuan Peng
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Hepatoblastoma, the most prevalent pediatric liver cancer, almost always carries a WNT-activating CTNNB1 mutation, yet exhibits notable molecular heterogeneity. To characterize this heterogeneity and identify novel targeted therapies, we per
Externí odkaz:
https://doaj.org/article/e9c310a9ac5d476ba9c8f3c8d25d32c8
Autor:
Rixt S. Bruinsma, Marta F. Fiocco, Wendy W. J. de Leng, Lennart A. Kester, Karin P. S. Langenberg, Godelieve A. M. Tytgat, Max M. van Noesel, Marc H. W. A. Wijnen, Alida F. W. van der Steeg, Ronald R. de Krijger
Publikováno v:
Journal of Molecular Pathology, Vol 5, Iss 3, Pp 304-318 (2024)
ALK is related to poor survival in neuroblastoma patients. We investigated the prognostic relevance of ALK mRNA expression and the relationship with ALK immunohistochemical expression, histological subtype and ALK aberrations. Whole transcriptome seq
Externí odkaz:
https://doaj.org/article/7650c5ee68724d7986d26e5dc5cc04ca
Autor:
Aimée S. R. Westerveld, Pien Roesthuis, Helena J. H. van der Pal, Dorine Bresters, Marc Bierings, Jacqueline Loonen, Andrica C. H. de Vries, Marloes Louwerens, Maria M. W. Koopman, Marry M. van den Heuvel-Eibrink, Margriet van der Heiden-van der Loo, Peter Hoogerbrugge, Geert O. Janssens, Ronald R. de Krijger, Cecile M. Ronckers, Rob Pieters, Leontien C. M. Kremer, Jop C. Teepen
Publikováno v:
Blood Cancer Journal, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract Acute lymphoblastic leukemia (ALL) survivors are at risk for developing subsequent neoplasms, but there is limited information on long-term risks and risk factors for both subsequent malignant neoplasms (SMNs) and subsequent non-malignant ne
Externí odkaz:
https://doaj.org/article/dd1578a6e4ab4a39aa7be9fb7ad260a1
Autor:
Sizzle F Vanterpool, Jasper V Been, Michiel L Houben, Peter G J Nikkels, Ronald R De Krijger, Luc J I Zimmermann, Boris W Kramer, Ann Progulske-Fox, Leticia Reyes
Publikováno v:
PLoS ONE, Vol 11, Iss 1, p e0146157 (2016)
Intrauterine presence of Porphyromonas gingivalis (Pg), a common oral pathobiont, is implicated in preterm birth. Our aim was to determine if the location of Pg within placental and/or umbilical cord sections was associated with a specific delivery d
Externí odkaz:
https://doaj.org/article/cd3248352b8948fdbe1368bb093299d5
Autor:
W Edward Visser, Cíntia R Bombardieri, Chantal Zevenbergen, Sander Barnhoorn, Alexandre Ottaviani, Ingrid van der Pluijm, Renata Brandt, Ellen Kaptein, Ramona van Heerebeek, Hans van Toor, George A Garinis, Robin P Peeters, Marco Medici, Willy van Ham, Wilbert P Vermeij, Monique C de Waard, Ronald R de Krijger, Anita Boelen, Joan Kwakkel, John J Kopchick, Edward O List, Joost P M Melis, Veerle M Darras, Martijn E T Dollé, Gijsbertus T J van der Horst, Jan H J Hoeijmakers, Theo J Visser
Publikováno v:
PLoS ONE, Vol 11, Iss 3, p e0149941 (2016)
DNA damage contributes to the process of aging, as underscored by premature aging syndromes caused by defective DNA repair. Thyroid state changes during aging, but underlying mechanisms remain elusive. Since thyroid hormone (TH) is a key regulator of
Externí odkaz:
https://doaj.org/article/ca420b0d4f254e4db9aa43c0a8d08565
Autor:
Johannes Hofland, Jacobie Steenbergen, Jacoba M Voorsluijs, Michael M P J Verbiest, Ronald R de Krijger, Leo J Hofland, Wouter W de Herder, Andre G Uitterlinden, Richard A Feelders, Frank H de Jong
Publikováno v:
PLoS ONE, Vol 9, Iss 8, p e104944 (2014)
Adrenocortical carcinoma (ACC) is a rare, but highly malignant tumor of unknown origin. Inhibin α-subunit (Inha) knockout mice develop ACCs following gonadectomy. In man, INHA expression varies widely within ACC tissues and its circulating peptide i
Externí odkaz:
https://doaj.org/article/e7169ff96a4e453ab98e920ee19a98b5
Autor:
Jasper V Been, Sizzle F Vanterpool, Jasmijn D E de Rooij, G Ingrid J G Rours, René F Kornelisse, Martien C J M van Dongen, Christel J A W van Gool, Ronald R de Krijger, Peter Andriessen, Luc J I Zimmermann, Boris W Kramer
Publikováno v:
PLoS ONE, Vol 7, Iss 10, p e46217 (2012)
BACKGROUND: Histological chorioamnionitis (HC) is an intrauterine inflammatory process highly associated with preterm birth and adverse neonatal outcome. HC is often clinically silent and diagnosed postnatally by placental histology. Earlier identifi
Externí odkaz:
https://doaj.org/article/07a46819237c49749cfec5e9c445dd38
Autor:
Caroline C.C. Hulsker, Maya Schulpen, Annelies M.C. Mavinkurve-Groothuis, Otto Visser, József Zsiros, Marc H.W. Wijnen, Ronald R. de Krijger, Annette H. Bruggink, Leendert H.J. Looijenga, Henrike E. Karim-Kos, Alida F.W. van der Steeg
Publikováno v:
EJC Paediatric Oncology, Vol 3, Iss , Pp 100148- (2024)
Background: Population-based studies assessing long-term patterns of incidence and disease characteristics of germ cell tumors (GCTs) in children are scarce. We investigated incidence and survival trends of malignant extracranial GCTs in children usi
Externí odkaz:
https://doaj.org/article/3d2b227095c7475cb0180235ba227e31