Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Ronald P. Wong"'
Autor:
María J. Cabello-Lobato, Cristina González-Garrido, María I. Cano-Linares, Ronald P. Wong, Aurora Yáñez-Vílchez, Macarena Morillo-Huesca, Juan M. Roldán-Romero, Marta Vicioso, Román González-Prieto, Helle D. Ulrich, Félix Prado
Publikováno v:
Cell Reports, Vol 36, Iss 4, Pp 109440- (2021)
Summary: The minichromosome maintenance (MCM) helicase physically interacts with the recombination proteins Rad51 and Rad52 from yeast to human cells. We show, in Saccharomyces cerevisiae, that these interactions occur within a nuclease-insoluble sca
Externí odkaz:
https://doaj.org/article/fc16006ac8644cb681297f621893f991
Autor:
Danielle M. Panelli, Xiaobin Wang, Jonathan Mayo, Ronald J. Wong, Xiumei Hong, Martin Becker, Nima Aghaeepour, Maurice L. Druzin, Barry S. Zuckerman, David K. Stevenson, Gary M. Shaw DrPH, Katherine Bianco
Publikováno v:
BMC Pregnancy and Childbirth, Vol 24, Iss 1, Pp 1-9 (2024)
Abstract Background Biologic strain such as oxidative stress has been associated with short leukocyte telomere length (LTL), as well as with preeclampsia and spontaneous preterm birth, yet little is known about their relationships with each other. We
Externí odkaz:
https://doaj.org/article/ccf7f3df54bb4ba0acfc1240ee729502
Autor:
Elizabeth K. Costello, Daniel B. DiGiulio, Anna Robaczewska, Laura Symul, Ronald J. Wong, Gary M. Shaw, David K. Stevenson, Susan P. Holmes, Douglas S. Kwon, David A. Relman
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/bc866d5a18f64f0f881c8512630d731b
Autor:
Danielle M. Panelli, Stephanie A. Leonard, Ronald J. Wong, Martin Becker, Jonathan A. Mayo, Erica Wu, Anna I. Girsen, Ian H. Gotlib, Nima Aghaeepour, Maurice L. Druzin, Gary M. Shaw, David K. Stevenson, Katherine Bianco
Publikováno v:
BMC Pregnancy and Childbirth, Vol 22, Iss 1, Pp 1-12 (2022)
Abstract Background Short leukocyte telomere length is a biomarker associated with stress and morbidity in non-pregnant adults. Little is known, however, about maternal telomere dynamics in pregnancy. To address this, we examined changes in maternal
Externí odkaz:
https://doaj.org/article/2189da191a8942789c90deeb5c9387a0
Autor:
Kévin Contrepois, Songjie Chen, Mohammad S. Ghaemi, Ronald J. Wong, The Alliance for Maternal and Newborn Health Improvement (AMANHI), The Global Alliance to Prevent Prematurity and Stillbirth (GAPPS), Gary Shaw, David K. Stevenson, Nima Aghaeepour, Michael P. Snyder
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract Assessment of gestational age (GA) is key to provide optimal care during pregnancy. However, its accurate determination remains challenging in low- and middle-income countries, where access to obstetric ultrasound is limited. Hence, there is
Externí odkaz:
https://doaj.org/article/e1e0213ab36143bcb8f2e51065371941
Autor:
Natalie Stanley, Ina A. Stelzer, Amy S. Tsai, Ramin Fallahzadeh, Edward Ganio, Martin Becker, Thanaphong Phongpreecha, Huda Nassar, Sajjad Ghaemi, Ivana Maric, Anthony Culos, Alan L. Chang, Maria Xenochristou, Xiaoyuan Han, Camilo Espinosa, Kristen Rumer, Laura Peterson, Franck Verdonk, Dyani Gaudilliere, Eileen Tsai, Dorien Feyaerts, Jakob Einhaus, Kazuo Ando, Ronald J. Wong, Gerlinde Obermoser, Gary M. Shaw, David K. Stevenson, Martin S. Angst, Brice Gaudilliere, Nima Aghaeepour
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-9 (2020)
Single-cell technologies are increasingly prominent in clinical applications, but predictive modelling with such data in large cohorts has remained computationally challenging. We developed a new algorithm, ‘VoPo’, for predictive modelling and vi
Externí odkaz:
https://doaj.org/article/e63eb4be164c423694059f87cd18e59d
Autor:
Ronald M.Y. Wong, Tsz-kiu Li, Jie Li, Wing-Tung Ho, Simon K.-H. Chow, Sharon S.Y. Leung, Wing-Hoi Cheung, Margaret Ip
Publikováno v:
Journal of Orthopaedic Translation, Vol 23, Iss , Pp 8-20 (2020)
Objective: Osteosynthesis-associated infection is a challenging complication post fracture fixation, burdening the patients and the orthopaedic surgeons alike. A clinically relevant animal model is critical in devising new therapeutic strategies. Our
Externí odkaz:
https://doaj.org/article/c011513e38ad4ffeb388e75b5b8ee45f
Autor:
Gary M Shaw, Xin Zhou, David K Stevenson, Sheeno Thyparambil, Shiying Hao, Xuefeng B Ling, Doff B McElhinney, John C Whitin, Harvey J Cohen, Karl G Sylvester, Jin You, Xiaoming Yao, Lihong Mo, Subhashini Ladella, Ronald J Wong, Zhen Li, Qianyang Huang, James Schilling, Wei-Li Liao, Shantay R Davies-Balch, Hangyi Zhao, David Fan
Publikováno v:
BMJ Open, Vol 11, Iss 11 (2021)
Objective This study aimed to develop a blood test for the prediction of pre-eclampsia (PE) early in gestation. We hypothesised that the longitudinal measurements of circulating adipokines and sphingolipids in maternal serum over the course of pregna
Externí odkaz:
https://doaj.org/article/81f96204b5804d3db0f402c0f9b67062
Autor:
Maide Ozen, Hui Zhao, Flora Kalish, Yang Yang, Lauren L Jantzie, Ronald J Wong, David K Stevenson
Publikováno v:
PLoS ONE, Vol 16, Iss 6, p e0252642 (2021)
Heme oxygenase-1 (HO-1) is an evolutionarily conserved stress response enzyme and important in pregnancy maintenance, fetal and neonatal outcomes, and a variety of pathologic conditions. Here, we investigated the effects of an exposure to systemic in
Externí odkaz:
https://doaj.org/article/29c7910acaa4428cb698e72e1631d67e
Autor:
Xiaoyuan Han, Mohammad S. Ghaemi, Kazuo Ando, Laura S. Peterson, Edward A. Ganio, Amy S. Tsai, Dyani K. Gaudilliere, Ina A. Stelzer, Jakob Einhaus, Basile Bertrand, Natalie Stanley, Anthony Culos, Athena Tanada, Julien Hedou, Eileen S. Tsai, Ramin Fallahzadeh, Ronald J. Wong, Amy E. Judy, Virginia D. Winn, Maurice L. Druzin, Yair J. Blumenfeld, Mark A. Hlatky, Cecele C. Quaintance, Ronald S. Gibbs, Brendan Carvalho, Gary M. Shaw, David K. Stevenson, Martin S. Angst, Nima Aghaeepour, Brice Gaudilliere
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Preeclampsia is one of the most severe pregnancy complications and a leading cause of maternal death. However, early diagnosis of preeclampsia remains a clinical challenge. Alterations in the normal immune adaptations necessary for the maintenance of
Externí odkaz:
https://doaj.org/article/d6c4dbcad99b424ba7d6e1e76d63d1d3