Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Ronald P. Magnusson"'
Publikováno v:
Journal of Lipid Research, Vol 49, Iss 3, Pp 612-624 (2008)
Long-chain 3-hydroxydicarboxylic acids (3-OHDCAs) are thought to arise via β-oxidation of the corresponding dicarboxylic acids (DCAs), although long-chain DCAs are neither readily transported into nor β-oxidized in mitochondria. We thus examined wh
Externí odkaz:
https://doaj.org/article/36b80259ebfc48d88f51150686f0d2be
Publikováno v:
Archives of Biochemistry and Biophysics. 407:176-183
Aspartyl aminopeptidase (DAP), a widely distributed and abundant cytosolic enzyme, removes glutamyl or aspartyl residues from N-terminal acidic amino acid-containing peptides. DAP is a member of the M18 family of the MH clan of cocatalytic metallopep
Publikováno v:
Archives of Biochemistry and Biophysics. 384:174-180
The proteasome activator PA28 (11S REG) is composed of two homologous subunits termed alpha and beta. The properties of the recombinant beta-subunit were explored and compared to the properties of the recombinant alpha-subunit. PA28beta produced in a
Publikováno v:
Archives of Biochemistry and Biophysics. 374:325-333
Inclusions containing ubiquitin-protein aggregates appear in neurons of patients with neurodegenerative disorders such as Alzheimer's disease and Parkinson's disease. The relationship between inclusion production and cell viability is not understood.
Publikováno v:
Archives of Biochemistry and Biophysics. 362:283-290
The peptidyl alcohol N-benzyloxycarbonyl-Ile-Glu(O-t-Bu)-Ala-leucinol is a mild activator of the chymotrypsin-like activity of the proteasome. When added to an incubation mixture of recombinant PA28alpha plus 20S proteasome the peptidyl alcohol antag
Publikováno v:
Molecular Biology Reports. 26:39-44
The degradation of chromogenic substrates and oligopeptides by the 20S proteasome is markedly enhanced and the generation of antigens for presentation by the MHC class-I system is facilitated by combination with an activator protein known as PA28 or
Publikováno v:
Journal of Biological Chemistry. 273:15961-15970
An aminopeptidase with a preference for N-terminal aspartyl and glutamyl residues but distinct from glutamyl aminopeptidase (EC 3.4.11.7) was purified to near homogeneity from rabbit brain cytosol. Its properties were similar to an enzyme described p
Publikováno v:
Molecular and Cellular Endocrinology. 93:199-206
The baculovirus expression system was used to overexpress recombinant human thyroid peroxidase. Sf-9 cells infected with the recombinant virus AcMNPV-hTPO synthesized hTPO protein (hTPO-bac) immunogenic on Western blots when probed with either rabbit
Publikováno v:
Acta Endocrinologica. 126:460-466
The effect of serum TSH on rat thyroid peroxidase mRNA levels was studied in order to investigate the regulation of thyroid peroxidase gene expression in vivo. A nearly full-length rat thyroid peroxidase cDNA clone was isolated from a bacteriophage c
Publikováno v:
Archives of biochemistry and biophysics. 478(1)
P450 enzymes comprising the human CYP4F gene subfamily are catalysts of eicosanoid (e.g., 20-HETE and leukotriene B4) formation and degradation, although the role that individual CYP4F proteins play in these metabolic processes is not well defined. T