Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Ronald Oude Elferink"'
Autor:
Jacqueline Langedijk, Erika Ivanna Araya, Amanda Ribeiro Barroso, Dagmar Tolenaars, Marc Nazaré, Hassane Belabed, Jens Schoene, Juliana Geremias Chichorro, Ronald Oude Elferink
Publikováno v:
Frontiers in Pain Research, Vol 3 (2022)
IntroductionThe G-protein coupled receptor LPAR5 plays a prominent role in LPA-mediated pain and itch signaling. In this study we focus on the LPAR5-antagonist compound 3 (cpd3) and its ability to affect pain and itch signaling, both in vitro and in
Externí odkaz:
https://doaj.org/article/b57a9af173bd488d918cfb9ed75bd1f1
Autor:
Jacqueline Langedijk, Ruth Bolier, Dagmar Tolenaars, Lysbeth ten Bloemendaal, Suzanne Duijst, Dirk de Waart, Ulrich Beuers, Piter Bosma, Ronald Oude Elferink
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract Pruritus is one of the most distressing symptoms in cholestatic patients. Plasma autotaxin (ATX) activity correlates with the severity of pruritus in cholestatic patients, but the pathophysiology is unclear. To study pruritus in mice, we mea
Externí odkaz:
https://doaj.org/article/8a91086451c548c488f3ed16188f6c17
Autor:
Remco van Dijk, Sem J. Aronson, Dirk R. de Waart, Stan F. van de Graaf, Suzanne Duijst, Jurgen Seppen, Ronald Oude Elferink, Ulrich Beuers, Piter J. Bosma
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-9 (2017)
Abstract We aimed to identify potent biliverdin reductase (BVRA) inhibitors as a novel concept for the treatment of severe unconjugated hyperbilirubinemia. 1280 FDA-approved compounds were screened in vitro for their ability to inhibit human and rat
Externí odkaz:
https://doaj.org/article/d12f4548a8564f6a914ed21b89937903
Autor:
Simon Hohenester, Veronika Kanitz, Andreas E. Kremer, Coen C. Paulusma, Ralf Wimmer, Helen Kuehn, Gerald Denk, David Horst, Ronald Oude Elferink, Ulrich Beuers
Publikováno v:
Cells, Vol 9, Iss 2, p 281 (2020)
Hydrophobic bile salts are considered to promote liver fibrosis in cholestasis. However, evidence for this widely accepted hypothesis remains scarce. In established animal models of cholestasis, e.g., by Mdr2 knockout, cholestasis and fibrosis are bo
Externí odkaz:
https://doaj.org/article/93e5f691fafa4d5787159a728bd64f6e
Publikováno v:
Oude Elferink, R P J & van de Graaf, S F J 2023, ' Bile Salts by the Back Road ', Cellular and Molecular Gastroenterology and Hepatology, vol. 16, no. 2 . https://doi.org/10.1016/j.jcmgh.2023.05.005
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2345b909a84170220b278189b4e51db
https://research.vumc.nl/en/publications/8595f6f1-2ded-446c-b7fc-46395da3d53b
https://research.vumc.nl/en/publications/8595f6f1-2ded-446c-b7fc-46395da3d53b
Publikováno v:
Hepatology, 76(3). John Wiley and Sons Ltd
Vartak, N, Elferink, R O, van de Graaf, S, Drasdo, D & Hengstler, J 2022, ' Reply ', Hepatology, vol. 76, no. 3, pp. E58 . https://doi.org/10.1002/hep.32485
Vartak, N, Elferink, R O, van de Graaf, S, Drasdo, D & Hengstler, J 2022, ' Reply ', Hepatology, vol. 76, no. 3, pp. E58 . https://doi.org/10.1002/hep.32485
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7cf85457a79290c6395e173d3ed59800
https://doi.org/10.1002/hep.32485
https://doi.org/10.1002/hep.32485
Autor:
Jacqueline, Langedijk, Erika Ivanna, Araya, Amanda Ribeiro, Barroso, Dagmar, Tolenaars, Marc, Nazaré, Hassane, Belabed, Jens, Schoene, Juliana Geremias, Chichorro, Ronald, Oude Elferink
Publikováno v:
Frontiers in pain research (Lausanne, Switzerland). 3
The G-protein coupled receptor LPARNociceptive behavior in wild type mice was induced by formalin, carrageenan or prostaglandin E2 (PGEAs expected, nociceptive behavior (induced by formalin, carrageenan or PGECpd3 has
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7fbe3cc2bad7f79e17f857c72b943a97
https://pubmed.ncbi.nlm.nih.gov/35959236
https://pubmed.ncbi.nlm.nih.gov/35959236
Autor:
David Trampert, Remco Kersten, Dagmar Tolenaars, Ronald Oude-Elferink, Stan van de Graaf, Ulrich Beuers
Publikováno v:
Journal of Hepatology. 77:S603-S604
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::714ec0fe0f750345774ab420d4b562f5
https://doi.org/10.1016/s0168-8278(22)01523-9
https://doi.org/10.1016/s0168-8278(22)01523-9
Autor:
Ulrich Beuers, Ronald Oude Elferink
Publikováno v:
Cellular and molecular gastroenterology and hepatology, 14(5), 1168-1169. Elsevier Inc.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62aa8df69751749f97a293d2980b06f1
https://doi.org/10.1016/j.jcmgh.2022.08.009
https://doi.org/10.1016/j.jcmgh.2022.08.009
Publikováno v:
Journal of Hepatology. 77:S761
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8467864afb1b2866e11370c6c31f47ee
https://doi.org/10.1016/s0168-8278(22)01839-6
https://doi.org/10.1016/s0168-8278(22)01839-6