Zobrazeno 1 - 10
of 92
pro vyhledávání: '"Ronald N. Harty"'
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Filovirus-host interactions play important roles in all stages of the virus lifecycle. Here, we identify LATS1/2 kinases and YAP, key components of the Hippo pathway, as critical regulators of EBOV transcription and egress. Specifically, we
Externí odkaz:
https://doaj.org/article/23875c06d84b41d29612e95e37cfb856
Autor:
Elizabeth Rybakovsky, Katherine M. DiGuilio, Mary Carmen Valenzano, Sophie Geagan, Kaithlyn Pham, Ronald N. Harty, James M. Mullin
Publikováno v:
Physiological Reports, Vol 11, Iss 7, Pp n/a-n/a (2023)
Abstract Using the 16HBE 14o‐ human airway epithelial cell culture model, calcitriol (Vitamin D) was shown to improve barrier function by two independent metrics – increased transepithelial electrical resistance (TER) and reduced transepithelial
Externí odkaz:
https://doaj.org/article/97551726850c4e4787451875ffb06e47
Autor:
Ariel Shepley-McTaggart, Michael Patrick Schwoerer, Cari A. Sagum, Mark T. Bedford, Chaitanya K. Jaladanki, Hao Fan, Joel Cassel, Ronald N. Harty
Publikováno v:
Viruses, Vol 13, Iss 2, p 288 (2021)
Filoviruses Ebola (EBOV) and Marburg (MARV) are devastating high-priority pathogens capable of causing explosive outbreaks with high human mortality rates. The matrix proteins of EBOV and MARV, as well as eVP40 and mVP40, respectively, are the key vi
Externí odkaz:
https://doaj.org/article/c5e17d7de27d46759d5f3ea2744a9919
Autor:
Ronald N. Harty, Takashi Irie, Yuliang Liu, Barbara S. Drolet, Elena Carnero, Adolfo García-Sastre
Publikováno v:
Viruses, Vol 4, Iss 9, Pp 1605-1618 (2012)
Vesicular stomatitis virus (VSV) is an important vector-borne pathogen of bovine and equine species, causing a reportable vesicular disease. The matrix (M) protein of VSV is multifunctional and plays a key role in cytopathogenesis, apoptosis, host pr
Externí odkaz:
https://doaj.org/article/a3eea8996c7c4c43ac0955b3b8893ba3
Autor:
Ziying Han, Michael P. Schwoerer, Philip Hicks, Jingjing Liang, Gordon Ruthel, Corbett T. Berry, Bruce D. Freedman, Cari A. Sagum, Mark T. Bedford, Sachdev S. Sidhu, Marius Sudol, Ronald N. Harty
Publikováno v:
Diseases, Vol 6, Iss 3, p 64 (2018)
Lassa fever virus (LFV) belongs to the Arenaviridae family and can cause acute hemorrhagic fever in humans. The LFV Z protein plays a central role in virion assembly and egress, such that independent expression of LFV Z leads to the production of vir
Externí odkaz:
https://doaj.org/article/22b99517ea814842b01368e5cb38d09b
Publikováno v:
Advances in Virology, Vol 2011 (2011)
Externí odkaz:
https://doaj.org/article/a52fd9e619de4e63b25a570c7a9adfa7
Publikováno v:
Advances in Virology, Vol 2011 (2011)
Virus-host interactions play key roles in promoting efficient egress of many RNA viruses, including Ebola virus (EBOV or “e”) and Marburg virus (MARV or “m”). Late- (L-) domains conserved in viral matrix proteins recruit specific host protein
Externí odkaz:
https://doaj.org/article/419ec54e7830494ca64ba722c729e528
Autor:
Francisco Castillo, Carles Corbi-Verge, Javier Murciano-Calles, Adela M. Candel, Ziying Han, Manuel Iglesias-Bexiga, Javier Ruiz-Sanz, Philip M. Kim, Ronald N. Harty, Jose C. Martinez, Irene Luque
Publikováno v:
Digibug. Repositorio Institucional de la Universidad de Granada
instname
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This research has been financed by grants BIO2016-78746-C2-1-R and PID2020-112895RB-100 from the Spanish Ministry of Education and Science (I.L.) including AEI/FEDER EU funds. R.N.H. was funded in part by National Institutes of Health grants AI138052
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1877c791c8c0c7dec7de3cd2d1417ad5
https://doi.org/10.1016/j.ijbiomac.2022.03.010
https://doi.org/10.1016/j.ijbiomac.2022.03.010
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 120(2)
The filovirus VP40 protein directs virion egress, which is regulated either positively or negatively by select VP40–host interactions. We demonstrate that host BAG3 and HSP70 recognize VP40 as a client and inhibit the egress of VP40 virus-like part
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15cf8e49bbcc8f0a05610a3e361bf243
https://pubmed.ncbi.nlm.nih.gov/36598950
https://pubmed.ncbi.nlm.nih.gov/36598950
Publikováno v:
Autophagy. :1-2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5fd74283c9cd60488e56154fa3d0a39d
https://doi.org/10.1080/15548627.2023.2178781
https://doi.org/10.1080/15548627.2023.2178781